GB2358352A - Bacterial extract as oral adjuvant - Google Patents

Bacterial extract as oral adjuvant

Info

Publication number
GB2358352A
GB2358352A GB0108406A GB0108406A GB2358352A GB 2358352 A GB2358352 A GB 2358352A GB 0108406 A GB0108406 A GB 0108406A GB 0108406 A GB0108406 A GB 0108406A GB 2358352 A GB2358352 A GB 2358352A
Authority
GB
United Kingdom
Prior art keywords
bacterial extract
oral adjuvant
oral
bacterial
adjuvant
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
GB0108406A
Other versions
GB0108406D0 (en
Inventor
William Leslie Porter
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of GB0108406D0 publication Critical patent/GB0108406D0/en
Publication of GB2358352A publication Critical patent/GB2358352A/en
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A61K2039/541—Mucosal route
    • A61K2039/542—Mucosal route oral/gastrointestinal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55505—Inorganic adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55555—Liposomes; Vesicles, e.g. nanoparticles; Spheres, e.g. nanospheres; Polymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55588—Adjuvants of undefined constitution
    • A61K2039/55594—Adjuvants of undefined constitution from bacteria

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

A killed bacterial preparation for oral administration to humans or animals, especially to enhance immune stimulation, more particularly comprising a lipid of controlled particle size such that the components of the bacterial cells are made available to immune sensitive areas of the body.
GB0108406A 1998-10-19 1999-10-19 Bacterial extract as oral adjuvant Withdrawn GB2358352A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9822619.4A GB9822619D0 (en) 1998-10-19 1998-10-19 Immune response stimulation
PCT/GB1999/003345 WO2000023106A1 (en) 1998-10-19 1999-10-19 Bacterial extract as oral adjuvant

Publications (2)

Publication Number Publication Date
GB0108406D0 GB0108406D0 (en) 2001-05-23
GB2358352A true GB2358352A (en) 2001-07-25

Family

ID=10840705

Family Applications (2)

Application Number Title Priority Date Filing Date
GBGB9822619.4A Ceased GB9822619D0 (en) 1998-10-19 1998-10-19 Immune response stimulation
GB0108406A Withdrawn GB2358352A (en) 1998-10-19 1999-10-19 Bacterial extract as oral adjuvant

Family Applications Before (1)

Application Number Title Priority Date Filing Date
GBGB9822619.4A Ceased GB9822619D0 (en) 1998-10-19 1998-10-19 Immune response stimulation

Country Status (3)

Country Link
AU (1) AU6349799A (en)
GB (2) GB9822619D0 (en)
WO (1) WO2000023106A1 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9930862D0 (en) * 1999-12-29 2000-02-16 Porter William L Immune response stimulation
CN102448488B (en) 2009-06-04 2014-10-15 独立行政法人产业技术综合研究所 Vaccine for mycoplasma infection
CN108841754B (en) * 2018-07-09 2021-12-07 东北农业大学 Fermentation culture method of biocontrol bacterium bacillus WXCDD105

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4076801A (en) * 1972-12-20 1978-02-28 Institut Pasteur Immunostimulant agent, compositions thereof and methods for their preparation
EP0432490A2 (en) * 1989-12-13 1991-06-19 Societe Des Produits Nestle S.A. Immunostimulant agent
US5336666A (en) * 1990-06-06 1994-08-09 Tsehay Neway Immunostimulant drug based on polar glyopeptidolipids of mycobacterium chelonae

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4076801A (en) * 1972-12-20 1978-02-28 Institut Pasteur Immunostimulant agent, compositions thereof and methods for their preparation
EP0432490A2 (en) * 1989-12-13 1991-06-19 Societe Des Produits Nestle S.A. Immunostimulant agent
US5336666A (en) * 1990-06-06 1994-08-09 Tsehay Neway Immunostimulant drug based on polar glyopeptidolipids of mycobacterium chelonae

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
(1974) 71 (2), 573-577., XP000876532 abstract page 573, right-hand column, line 4-22 *
FAUVE R M ET AL: "IMMUNO STIMULATION WITH BACTERIAL PHOSPHO LIPID EXTRACTS." PROC NATL ACAD SCI USA, *

Also Published As

Publication number Publication date
GB9822619D0 (en) 1998-12-09
GB0108406D0 (en) 2001-05-23
AU6349799A (en) 2000-05-08
WO2000023106A1 (en) 2000-04-27

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Legal Events

Date Code Title Description
WAP Application withdrawn, taken to be withdrawn or refused ** after publication under section 16(1)