GB2343845A - Method and apparatus for use in prostate cryosurgery - Google Patents
Method and apparatus for use in prostate cryosurgery Download PDFInfo
- Publication number
- GB2343845A GB2343845A GB9823404A GB9823404A GB2343845A GB 2343845 A GB2343845 A GB 2343845A GB 9823404 A GB9823404 A GB 9823404A GB 9823404 A GB9823404 A GB 9823404A GB 2343845 A GB2343845 A GB 2343845A
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- Prior art keywords
- guide
- sound
- patient
- prostate
- cryosurgical
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B18/02—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by cooling, e.g. cryogenic techniques
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B2017/00017—Electrical control of surgical instruments
- A61B2017/00022—Sensing or detecting at the treatment site
- A61B2017/00084—Temperature
- A61B2017/00092—Temperature using thermocouples
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/00234—Surgical instruments, devices or methods, e.g. tourniquets for minimally invasive surgery
- A61B2017/00238—Type of minimally invasive operation
- A61B2017/00274—Prostate operation, e.g. prostatectomy, turp, bhp treatment
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B2017/00535—Surgical instruments, devices or methods, e.g. tourniquets pneumatically or hydraulically operated
- A61B2017/00557—Surgical instruments, devices or methods, e.g. tourniquets pneumatically or hydraulically operated inflatable
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/34—Trocars; Puncturing needles
- A61B17/3403—Needle locating or guiding means
- A61B2017/3405—Needle locating or guiding means using mechanical guide means
- A61B2017/3411—Needle locating or guiding means using mechanical guide means with a plurality of holes, e.g. holes in matrix arrangement
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00005—Cooling or heating of the probe or tissue immediately surrounding the probe
- A61B2018/00041—Heating, e.g. defrosting
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00315—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for treatment of particular body parts
- A61B2018/00547—Prostate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B18/02—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by cooling, e.g. cryogenic techniques
- A61B2018/0231—Characteristics of handpieces or probes
- A61B2018/0262—Characteristics of handpieces or probes using a circulating cryogenic fluid
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- Health & Medical Sciences (AREA)
- Surgery (AREA)
- Life Sciences & Earth Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medical Informatics (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Otolaryngology (AREA)
- Molecular Biology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Surgical Instruments (AREA)
- Thermotherapy And Cooling Therapy Devices (AREA)
Abstract
For accurate positioning of one or more cryosurgical probes during prostate cryosurgery, a urethral sound 34 is disclosed for insertion into the patient's urethra up to the bladder 16. A guide 30 is attached to the proximal end of the sound. One or more cryosurgical probes are then inserted through selected guide bores 46 of the guide. The guide bores control the location and angle of insertion of the probes through the patient's skin. The urethral sound provides an accurate position reference for the guide, so that the tips of the probes can be guided accurately to the region of the prostate 22.
Description
METHOD AND APPARATS FOR USE IN
PROSTATE CRYOSURGERY
This invention relates to a method and apparatus for use in prostate cryosurgery.
Fig. 1 illustrates a conventional technique for placement of cryosurgical probes for prostate surgery. The patient 10 is laid on his back with his legs 12 in a raised position. In Fig. 1, the patient's rectum, bladder, urethra, penis and prostate are denoted by numerals 14,16,18,20 and 22, respectively. An ultrasound imaging device 24 is inserted into the rectum 14 to image the area of the prostate 22. The surgeon then inserts cryosurgical probes 26 through the patient's skin to reach the prostate 22, using the ultrasound image produced by the imaging device 24 for guidance. The probes 26 are cooled by passing a suitable cryogen, for example, liquid nitrogen, through the tip; this can achieve temperatures of around-196 C to ablate the prostate.
A problem which severely limits the effectiveness of the operation is the difficulty in placing the cryosurgical probes 26 at precisely the correct positions relative to the prostate 22. The ultrasound imaging device 24 can produce only a very simple 2-dimensional image"slice", and so does not provide the surgeon with complete 3-dimensional information needed to position the probes 26 accurately. The positioning is dependent entirely on the skill and experience of the surgeon, who has manually to position, angle, and determine the depth of insertion, for each probe.
Since the prostate is buried beneath the skin, even a small angular deviation of the probe can cause the probe tip to miss the desired target region, and result in freezing of only a part of the prostate. Not only does this reduce the effectiveness of the operation, it also endangers the surrounding tissue, such as the urethra and the rectum. A fistula (which is a combined hole in the urethra and the rectum through which body waste can leak from one to the other) can be created, which is very unpleasant for the patient. Fistulas can only be corrected by lengthy and expensive further surgery.
A urethral warmer, and a rectal warmer, can be inserted in the urethra and rectum, respectively, to try to prevent unwanted freezing in those areas. Such warmers are described, for example, in commonly owned published International patent application WO-A-95/29643. However, such warmers are intended to provide only secondary protection, and may not be fully effective against direct freezing if the probe is positioned incorrectly very close to the urethra or to the rectum.
The present invention has been devised bearing the above problems in mind.
Broadly speaking, a first aspect of the invention provides apparatus for use in a cryosurgical prostate operation, comprising:
a member insertable into a patient's urethra; and
means for guiding insertion of one or more cryosurgical devices based on the position of the member.
The invention makes use of the inventors'appreciation that, in the vast majority of all males, the distance between the prostate and the bladder is substantially the same.
To the nearest centimetre, this distance is about 21 millimetres. Moreover, the urethra passes through the prostate. Therefore, by positioning the member (also referred to herein as a"sound") in the urethra relative to the bladder, the member also becomes positioned relative to the prostate. This provides a simple, yet extremely effective, technique for establishing a good positional reference with respect to the patient's prostate.
Preferably, the member is connectable to the guide to establish a predetermined geometry between the guide and the member. Preferably, the guide is in the form of one or more wall portions through which extend guide bores. The cryosurgical devices can be inserted through selected bores, the bores constraining the device to be inserted at a certain angle with respect to the urethral member (sound).
Urethral sounds are currently used for inserting catheters into the urethra and bladder. For example, such a sound would be used to insert the urethral warmer catheter mentioned previously. However, once the catheter is in position, the sound is removed and plays no further role.
In a second aspect, the invention provides a urethral sound comprising a tubular member insertable into a patient's urethra, and a coupling arrangement at a proximal end of said tubular member for forming a rigid coupling to a guide frame to provide a positional reference for guiding insertion of cryosurgical probes for prostate cryosurgery.
In a third aspect, the invention provides a guide for guiding one or more cryosurgical probes for prostate surgery, the guide comprising:
at least one wall portion having guide bores extending therethrough, through which the cryosurgical probes may be inserted, each guide bore having a respective diameter which is sufficiently small, and a length which is sufficiently long, to constrain the probe to a predetermined angled path as it is inserted through the bore.
In a further aspect, the invention provides apparatus for prostate cryosurgery, comprising:
a member insertable into a patient's urethra;
a plurality of cryosurgical probes; and
a guide connectable to the member for guiding insertion of the cryosurgical probes to the prostate region, based on the position of the member in the patient's urethra.
In a yet further aspect, the invention provides a method of positioning a cryosurgical probes in a patient for prostate surgery; comprising:
inserting a member into the patient's urethra;
coupling a guide to the member such that the member provides a reference position for the guide; and
using the guide to control the location and angle at which the cryosurgical probe is inserted into the patient, whereby the probe is positioned with its tip adjacent to the prostate.
In a further aspect, the invention provides a method of performing prostate cryosurgery in a patient, comprising:
inserting a member into the patient's urethra;
coupling a guide to the member such that the member provides a reference position for the guide;
inserting a first cryosurgical probe through a first selected guide bore of the guide and into the patient's skin, the guide bore controlling the location and angle of insertion into the patient such that the probe tip is positioned at a first position adjacent to the prostate;
inserting a second cryosurgical probe through a second selected guide bore of the guide and into the patient's skin, the second guide bore controlling the location and angle of insertion into the patient such that the probe tip is positioned at a second position adjacent to the prostate; and
passing cryogen fluid through the cryosurgical probes to oblate the prostate.
Embodiments of the invention are now described, by way of example only, with reference to the accompanying further drawings, in which:
Fig. 2 is a schematic view showing an embodiment of apparatus for positioning the cryosurgical probes;
Fig. 3 is an enlarged schematic view of the guide wall of Fig. 2;
Fig. 4 is a schematic side view of a first embodiment of urethral sound;
Fig. 5 is a schematic side view of a second embodiment of urethral sound;
Fig. 6 is a schematic side view of a third embodiment of urethral sound; and
Fig. 7 is a schematic side view of a fourth embodiment of a urethral sound.
Referring to Fig. 2, the same reference numerals as those used in Fig. l have been used again where appropriate. In this embodiment, positioning of the cryosurgical probes 26 is aided by the use of a guide frame 30 supported on the operating table 32 on which the patient is laid. In order that the frame 30 can be used for accurate guidance of the probes 26, it is necessary to align the frame 30 relative to the patient's prostate 22. This is achieved by means of a urethral sound 34 which is inserted into the patient's penis 20 and advanced along the urethra 18 to the bladder 16. (In Fig. 2, the urethral sound 34 is shown shaded for clarity. However, it is to be understood that the sound 34 is tubular rather than solid). This embodiment exploits the inventors' appreciation that, in the vast majority of all males, the distance between the bladder 16 and the prostate 22 appears to be the same (at least to about the nearest half centimetre or less). This distance is approximately 21 millimetres.
Therefore, by positioning the urethral sound 34 relative to the bladder 16, the sound 34 is positioned relative to the prostate 22 which surrounds the urethra 18 at a know distance from the bladder 16. The sound 34 can thus provide a known reference position for the prostate 22.
As described hereinbefore, urethral sounds are known per se, and have previously been used for inserting a catheter along the urethra to the bladder. Once the catheter is in position, the sound is then usually removed. In contrast, in this embodiment, the sound 34 is left in position to provide a known position reference for the prostate 22.
Once the urethral sound 34 has been manoeuvred into position, its proximal end is coupled mechanically to the guide frame 30. The coupling arrangement couples the sound 34 rigidly to the frame 30, at predetermined angle, such that the frame 30 has a predetermined fixed geometrical relationship with the sound 34. For example, the coupling arrangement may be a spigot and socket system (a spigot on the proximal end of the sound 34 being received in a socket in the frame 30), or it may be a bayonet type coupling.
Thereafter, the cryosurgical probes 26 may be inserted through guide bores 46 in the frame, to be guided at a predetermined angle, such that the tip of the probe will be positioned in the region of the prostate 22.
Referring to Fig. 3, the frame 30 may, for example, be angled, and consist of first and second walls 40 and 42 secured together by brackets 44. In this embodiment, the brackets 44 have a fixed angle but, in other embodiments, the brackets 44 might be adjustable to suit the patient. The brackets would then be locked at a predetermined angle to achieve a known geometrical relationship with the urethral sound 34.
In this embodiment, the walls 40 and 42 each have an arrangement of guide bores 46 through which a cryosurgical probe 26 may be inserted. (In. Fig. 3, only a selection of the bores are shown in full length, for the sake of clarity in the drawing).
Each bore 46 is dimensioned to be slightly larger than the diameter of the probe 26, so that the probe may be slid easily therethrough, but at an angle defined precisely by the bore 46. Typically, the bores 46 will be arranged in a grid pattern; the spacing between adjacent bores 46 defines the"resolution"to which an individual probe 26 may be positioned.
Within each wall 40 and 42, the guide bores 46 may be generally parallel to each other, or the bores may be inclined relative to each other to define a curve such that the probes will tend to converge towards the prostate 22.
One of the factors affecting the positioning accuracy of the frame 30, is the thickness of the walls 40 and 42. If the walls 40 and 42 are too thin, they might not be effective in controlling the angle of insertion sufficiently accurately. The cryosurgical probes 26 used for prostate surgery are generally of about 3-5 millimetres in diameter, and for such probes, it is suggested that the wall thickness be at least 10 millimetres.
In this embodiment, the walls 40 and 42 are transparent, so that the surgeon's view of the patient, especially in the regions in which the probes are inserted, is not hindered.
Preferably, the walls 40 and 42 are of a material on which a surgeon can mark graphically an outline corresponding to the prostate. As is usual in prostate cryosurgery, the prostate is mapped prior to the operation, for example, using ultrasound, so that its size can be determined. This pre-operation mapping may also be useful in further defining the distance between the prostate and the bladder in the patient. In this embodiment, the lower wall 42 has a socket aperture 48 for receiving the proximal end of the urethral sound.
Although the illustrated embodiment includes first and second discrete walls 40 and 42, each of which is generally planar. In other embodiments, the walls 40 and 42 may be curved, and may, for example, be integrally formed as single generally continuous wall. In particular, if the wall has a generally constant radius of curvature, then it may be regarded as corresponding to a magnified profile of the prostate, which might aid graphical mapping of the prostate area onto the wall surface, and positioning of the probes.
Figure 4 illustrates a first embodiment of urethral sound 34. The sound consists of a tubular member 50 having a smoothly rounded distal tip 52 to aid insertion along the urethra. The proximal end 54 has a spigot portion 55 for insertion in the socket aperture 48 of the frame 30.
The region 56 of the sound 34 between the dotted lines 58 corresponds to the position of the prostate when the tip 52 is advanced to the patient's bladder. This region 56 is spaced a distance d=21 mm from the tip 52. In this embodiment, thermocouples 60 are provided on the surface of the tubular member 50 for monitoring the temperature of the urethra wall within the prostate during the freezing operation.
The thermo couples 60 are coupled by wires (not shown) extending through the proximal end 54 to suitable temperature monitoring apparatus (known per se).
During the freezing operation, the urethra should not itself be frozen, as this would damage the urethra wall tissue. The thermocouples 60 enable the most vulnerable part of the urethra to be monitored during freezing and, if the urethra is in danger of being frozen, the cooling effect of the probes can be reduced accordingly (for example, by reducing the rate of cryogen flow). This enables the maximum amount of cooling to be used which does not itself threaten the vulnerable urethral wall tissue.
The thermocouples 60 are preferably positioned around substantially the entire circumference of the member 50, so that the temperature can be measured from all sides. Additionally, the thermocouples 60 are preferably arranged at a number of different axial positions, so that the temperature of the urethral wall can be measured at different points along its length.
Fig. 5 illustrates a modified second embodiment of urethral sound 34. This is very similar to that illustrated in Fig. 4, except that the distal end of the sound is curved at right angles to the main longitudinal axis. Such a shape can provide a positive locating effect when the tip reaches the bladder, and prevent accidental movement of the sound during the cryosurgical operation.
Fig. 6 illustrates a third embodiment of urethral sound 34, which is similar to that of Fig. 4 but functions also as a urethral warmer to provide secondary thermal protection for the urethra and bladder. In this embodiment, an inflatable membrane 62 is provided at the distal tip of the sound 34, and a second inflatable membrane 64 is provided in the region 56. In use, the membranes 62 and 64 are inflated by circulating a heated solution of, for example, sterile saline, through internal conduits (not shown) leading to the membranes 62 and 64. As well as providing the aforementioned warming effect, the membrane 62 at the tip of the sound 34 will expand into the bladder, and thus provide a positive locating effect to prevent accidental withdrawal of the sound.
The thermocouple sensors 60 are preferably located on the membrane material, so that inflation of the membrane will press the thermocouple sensors into contact with the wall of the urethra. The membrane 64 may extend on only one side of the sound 34 (as illustrated), or it may project through apertures on all sides of the sound 34. As a further alternative, the membrane may be formed as a sleeve surrounding the section 56 of the sound 34, and be inflated by fluid entering the membrane through one or more first apertures (not shown) and exiting by one or more second apertures (not shown).
Fig. 7 illustrates a fourth embodiment of urethral sound 34 which is, in effect, a combination of the embodiments of Figs. 5 and 6. The same reference numerals have been used to denote the features described above.
In use, different sizes (i. e. different lengths and different diameters) of urethral sound 34 will be available, and the surgeon will select the most appropriate size of sound for the patient. In general, the surgeon should use the largest diameter sound 34 which can be safely manoeuvred through the penis and urethra to the bladder. The large diameter will minimise the chances of unwanted movement while in position, and provide good thermal contact with the urethral wall.
The urethral sound 34 may be made of any suitable material, for example, of plastics or of stainless steel. The sound 34 may be intended to be disposa after only one use, or may be intended to be sterilised and used again for a limited number of operations.
It will be appreciated that the above embodiments are merely illustrative, and are not intended to limit the scope of the invention. In particular, many different mechanical coupling, mounting, and guiding arrangements may be used other than those described above.
It will be appreciated that the invention, particularly as described in the preferred embodiments, can provide a simple, yet very effective, technique for positioning one or more cryosurgical probes accurately with respect to a patient's prostate. The invention can eliminate common positioning errors, and significantly reduce the risks of accidental damage to the patient's urethra, rectum and bladder.
Moreover, the accurate positioning can enable the surgeon better to target specific regions of the prostate with individual cryosurgical probes, leading to more effective surgery. The preferred designs also enable the temperature of the urethra in the region of the prostate to be monitored accurately.
Claims (35)
- CLAIMS 1. Apparatus for use in a cryosurgical prostate operation, comprising: a member insertable into a patient's urethra; and a guide for guiding insertion of one or more cryosurgical devices based on the position of the member.
- 2. Apparatus according to claim 1, comprising a coupling for forming a rigid connection between the member and the guide.
- 3. Apparatus according to claim 1, wherein the guide comprises at least one wall having guide bores therein through which cryosurgical devices may be inserted.
- 4. Apparatus according to claim 1, wherein the guide comprises a first wall portion and a second wall portion arranged at a predetermined angle thereto, for enabling cryosurgical devices to be inserted from two different directions.
- 5. Apparatus according to claim 1, wherein the member comprises a distal end portion and a proximal end portion, the proximal end portion having a coupling arrangement thereon for forming a rigid connection to the guide.
- 6. Apparatus according to claim 1, wherein the member comprises at least one temperature sensor for measuring the temperature of the urethral wall.
- 7. Apparatus according to claim 6, wherein said temperature sensor is positioned on said member such that, when the member is fully inserted in the urethra to the bladder, the temperature sensor is located in the region of the prostate.
- 8. Apparatus according to claim 6, wherein the member comprises a plurality of temperature sensors arranged at different circumferential positions around the member.
- 9. Apparatus according to claim 6, wherein the member comprises a plurality of temperature sensors arranged at different axial positions on the member.
- 10. Apparatus according to claim 1, wherein the member comprises a distal inflatable membrane, a first conduit coupling within the member for carrying fluid to the membrane, and a second conduit within the member for carrying fluid away from the membrane.
- 11. Apparatus according to claim 1, wherein the member comprises at least one inflatable membrane at an intermediate position between the distal and proximal ends of the member, a first conduit within the member for carrying fluid to the membrane, and a second conduit within the member for carrying fluid away from the membrane.
- 12. Apparatus according to claim 1, wherein the member comprises an axis, a distal end region and a proximal end region, wherein the distal end region is bent substantially at right angles to said axis of the member.
- 13. A urethral sound comprising a tubular member insertable into a patient's urethra, and a coupling arrangement at a proximal end of said tubular member for forming a rigid coupling to a guide frame to provide a positional reference for guiding insertion of cryosurgical probes for prostate cryosurgery.
- 14. A urethral sound according to claim 12, wherein the sound carries at least one temperature sensor for measuring the temperature of the urethral wall.
- 15. A urethral sound according to claim 13, wherein the said temperature sensor is positioned on said sound such that when the sound is fully inserted in the urethra to the bladder, the temperature sensor is located in the region of the prostate.
- 16. A urethral sound according to claim 13, wherein the sound comprises a distal inflatable membrane, a first conduit within the sound for carrying fluid to the membrane, and a second conduit within the sound for carrying fluid away form the membrane.
- 17. A urethral sound according to cula, m 13, wherein the sound comprises at least one inflatable membrane at an intermediate position between the distal and proximal ends of the member, a first conduit within the sound for carrying fluid to the membrane and a second conduit within the sound for carrying the fluid away from the membrane.
- 18. A urethral sound according to claim 13, wherein the distal end of the member is bent generally to right angles to a main axis of the sound.
- 19. A guide for guiding one or more cryosurgical probes for prostate surgery, the guide comprising: at least one wall portion having guide bores extending therethrough, through which the cryosurgical probes may be inserted, each guide bore having a respective diameter which is sufficiently small, and a length which is sufficiently long, to constrain the probe to a predetermined angled path as it is inserted through the bore.
- 20. A guide according to claim 19, further comprising a coupling arrangement for forming a connection to a urethral sound to establish a predetermined geometrical relationship with the urethral sound.
- 21. A guide according to claim 19, wherein said wall portion is of transparent material.
- 22. A guide according to claim 19, wherein said guide bores are arranged in a grid pattern.
- 23. A guide according to claim 19, wherein the guide bores extend at different inclinations through said wall portion.
- 24. A guide according to claim 19, wherein the guide comprises a first wall portion, and a second wall portion arranged at a predetermined angle relative to said first wall portion, for enabling cryosurgical probes to be inserted from different directions.
- 25. Apparatus for prostate cryosurgery, comprising: a member insertable into a patient's urethra; a plurality of cryosurgical probes; and a guide connectable to the member for guiding insertion of the cryosurgical probes to the prostate region, based on the position of the member in the patient's urethra.
- 26. Apparatus according to claim 25, wherein the cryosurgical probes are liquid nitrogen cooled probes.
- 27. A method of positioning a cryosurgical probes in a patient for prostate surgery; comprising: inserting a member into the patient's urethra; coupling a guide to the member such that the member provides a reference position for the guide; and using the guide to control the location and angle at which the cryosurgical probe is inserted into the patient, whereby the probe is positioned with its tip adjacent to the prostate.
- 28. A method according to claim 27, wherein the step of inserting the member comprises advancing the member until a distal end of the member reaches the patient's bladder.
- 29. A method according to claim 28, further comprising the step of passing fluid into the member to inflate a membrane at the distal end of the member, to positively retain the distal end at the bladder.
- 30. A method according to claim 27, wherein the step of using the guide comprises inserting the cryosurgical probe through a guide bore in the guide to control the location and angle of insertion.
- 31. A method according to claim 29, further comprising inserting a second cryosurgical probe through a second guide bore to locate the second cryosurgical probe at a different position in the patient.
- 32. A method of performing prostate cryosurgery in a patient, comprising: inserting a member into the patient's urethra; coupling a guide to the member such that the member provides a reference position for the guide; inserting a first cryosurgical probe through a first selected guide bore of the guide and into the patient's skin, the guide bore controlling the location and angle of insertion into the patient such that the probe tip is positioned at a first position adjacent to the prostate; inserting a second cryosurgical probe through a second selected guide bore of the guide and into the patient's skin, the second guide bore controlling the location and angle of insertion into the patient such that the probe tip is positioned at a second position adjacent to the prostate; and passing cryogen fluid through the cryosurgical probes to oblate the prostate.
- 33. A method according to claim 32, further comprising the step of monitoring an output from at least one temperature sensor carried on the member indicative of the temperature of the patient's urethra in the vicinity of the prostate, and controlling the rate of flow of the cryogen to the cryosurgical probes in the response to the temperature indicative output.
- 34. A method according to claim 3r, further comprising circulating a heated fluid through the conduits in the member to inflate at least one thermal membrane carried by the member, to apply heat to a localised region of the urethra.
- 35. An appparatus or method substantially or hereinafter described with reference to any of Figs. 2 to 7 of the accompanying drawings.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
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GB9823404A GB2343845A (en) | 1998-10-26 | 1998-10-26 | Method and apparatus for use in prostate cryosurgery |
Applications Claiming Priority (1)
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GB9823404A GB2343845A (en) | 1998-10-26 | 1998-10-26 | Method and apparatus for use in prostate cryosurgery |
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GB9823404D0 GB9823404D0 (en) | 1998-12-23 |
GB2343845A true GB2343845A (en) | 2000-05-24 |
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GB9823404A Withdrawn GB2343845A (en) | 1998-10-26 | 1998-10-26 | Method and apparatus for use in prostate cryosurgery |
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US9839555B2 (en) | 2012-04-24 | 2017-12-12 | Urogyn B.V. | Applicator for delivering an occluding compound in a fallopian tube |
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US5494039A (en) * | 1993-07-16 | 1996-02-27 | Cryomedical Sciences, Inc. | Biopsy needle insertion guide and method of use in prostate cryosurgery |
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1998
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US4576175A (en) * | 1983-09-06 | 1986-03-18 | Moshe Epstein | Biopsy attachment for ultrasonic probe |
US5494039A (en) * | 1993-07-16 | 1996-02-27 | Cryomedical Sciences, Inc. | Biopsy needle insertion guide and method of use in prostate cryosurgery |
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Cited By (7)
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EP1247541A1 (en) * | 2001-04-03 | 2002-10-09 | Subrahmanyam Dr. Radhakrishna | Needle with guide means |
EP1929972A1 (en) * | 2006-12-05 | 2008-06-11 | I.A.L.T. S.c.r.l. | A kit of optical fibers for percutaneous ablative treatment |
WO2008068789A1 (en) * | 2006-12-05 | 2008-06-12 | Elesta S.R.L. | A kit of optical fibers for percutaneous ablative treatment |
US8265446B2 (en) | 2006-12-05 | 2012-09-11 | Elesta S.R.L. | Kit of optical fibers for percutaneous ablative treatment |
WO2013160347A1 (en) * | 2012-04-24 | 2013-10-31 | Urogyn B.V. | Bulking agent applicator for treating female urinary incontinence |
US9775622B2 (en) | 2012-04-24 | 2017-10-03 | Urogyn B.V. | Bulking agent applicator for treating female urinary incontinence |
US9839555B2 (en) | 2012-04-24 | 2017-12-12 | Urogyn B.V. | Applicator for delivering an occluding compound in a fallopian tube |
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GB9823404D0 (en) | 1998-12-23 |
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