GB2336733A - Apparatus for measuring microvascular blood flow - Google Patents

Apparatus for measuring microvascular blood flow

Info

Publication number
GB2336733A
GB2336733A GB9909639A GB9909639A GB2336733A GB 2336733 A GB2336733 A GB 2336733A GB 9909639 A GB9909639 A GB 9909639A GB 9909639 A GB9909639 A GB 9909639A GB 2336733 A GB2336733 A GB 2336733A
Authority
GB
United Kingdom
Prior art keywords
tissue
blood flow
scattered
light
microvascular blood
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
GB9909639A
Other versions
GB2336733B (en
GB9909639D0 (en
Inventor
David Boggett
Xiabing Huang
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
MOOR INSTR Ltd
Moor Instruments Ltd
Original Assignee
MOOR INSTR Ltd
Moor Instruments Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9623363.0A external-priority patent/GB9623363D0/en
Application filed by MOOR INSTR Ltd, Moor Instruments Ltd filed Critical MOOR INSTR Ltd
Priority to GB0023213A priority Critical patent/GB2351197B/en
Priority to GB9909639A priority patent/GB2336733B/en
Publication of GB9909639D0 publication Critical patent/GB9909639D0/en
Publication of GB2336733A publication Critical patent/GB2336733A/en
Application granted granted Critical
Publication of GB2336733B publication Critical patent/GB2336733B/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/72—Signal processing specially adapted for physiological signals or for diagnostic purposes
    • A61B5/7203—Signal processing specially adapted for physiological signals or for diagnostic purposes for noise prevention, reduction or removal
    • A61B5/7207—Signal processing specially adapted for physiological signals or for diagnostic purposes for noise prevention, reduction or removal of noise induced by motion artifacts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/02—Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
    • A61B5/026—Measuring blood flow
    • A61B5/0261—Measuring blood flow using optical means, e.g. infrared light

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Pathology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Physiology (AREA)
  • Veterinary Medicine (AREA)
  • Physics & Mathematics (AREA)
  • Public Health (AREA)
  • Biophysics (AREA)
  • Signal Processing (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Surgery (AREA)
  • General Health & Medical Sciences (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Artificial Intelligence (AREA)
  • Psychiatry (AREA)
  • Hematology (AREA)
  • Cardiology (AREA)
  • Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)

Abstract

An apparatus for measuring microvascular blood flow in tissue comprises means for irradiating a section of the tissue with the monochromatic light from the light source (2); means (2) for photodetecting the collected scattered light; means (3-6) for calculating the power spectrum of the photocurrents generated in the detection of laser light scattered from static tissue and Doppler broadened laser light scattered from moving blood cells. The apparatus includes means for filtering movement artefact noise and, therefore, enables fast tissue blood perfusion imaging with enhanced signal quality.
GB9909639A 1996-11-09 1997-11-07 Apparatus for measuring microvascular blood flow Expired - Fee Related GB2336733B (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
GB0023213A GB2351197B (en) 1996-11-09 1997-11-07 Apparatus for measuring microvascular blood flow
GB9909639A GB2336733B (en) 1996-11-09 1997-11-07 Apparatus for measuring microvascular blood flow

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB9623363.0A GB9623363D0 (en) 1996-11-09 1996-11-09 Apparatus for measuring microvascular blood flow
PCT/GB1997/003074 WO1998020794A1 (en) 1996-11-09 1997-11-07 Apparatus for measuring microvascular blood flow
GB9909639A GB2336733B (en) 1996-11-09 1997-11-07 Apparatus for measuring microvascular blood flow

Publications (3)

Publication Number Publication Date
GB9909639D0 GB9909639D0 (en) 1999-06-23
GB2336733A true GB2336733A (en) 1999-10-27
GB2336733B GB2336733B (en) 2001-02-21

Family

ID=26310371

Family Applications (2)

Application Number Title Priority Date Filing Date
GB9909639A Expired - Fee Related GB2336733B (en) 1996-11-09 1997-11-07 Apparatus for measuring microvascular blood flow
GB0023213A Expired - Fee Related GB2351197B (en) 1996-11-09 1997-11-07 Apparatus for measuring microvascular blood flow

Family Applications After (1)

Application Number Title Priority Date Filing Date
GB0023213A Expired - Fee Related GB2351197B (en) 1996-11-09 1997-11-07 Apparatus for measuring microvascular blood flow

Country Status (1)

Country Link
GB (2) GB2336733B (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6745066B1 (en) * 2001-11-21 2004-06-01 Koninklijke Philips Electronics, N.V. Measurements with CT perfusion
SE0501078L (en) * 2005-05-12 2006-11-13 Spectracure Ab A device for analyzing a fluid flow
JP6820706B2 (en) * 2016-09-27 2021-01-27 京セラ株式会社 Electronics, control methods and programs
CN110988908B (en) * 2019-12-19 2023-06-09 长光卫星技术股份有限公司 Quantitative analysis method for imaging influence of spectral shift of optical filter on space optical remote sensor

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4590948A (en) * 1984-01-20 1986-05-27 Perimed Kb Method and apparatus for measuring the blood flow in the superficial blood vessels of tissue
US4596254A (en) * 1984-12-18 1986-06-24 Tsi Research Associates Limited Partnership Laser Doppler flow monitor
WO1990011044A1 (en) * 1989-03-29 1990-10-04 National Research Development Corporation Blood flow determination
WO1991006244A1 (en) * 1989-10-31 1991-05-16 Gert Nilsson A system and a method for measurement and presentation of fluid flow movements, particularly the flow of blood through a body organ
US5598841A (en) * 1993-09-24 1997-02-04 Kowa Company Ltd. Blood flow measurement system

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4590948A (en) * 1984-01-20 1986-05-27 Perimed Kb Method and apparatus for measuring the blood flow in the superficial blood vessels of tissue
US4596254A (en) * 1984-12-18 1986-06-24 Tsi Research Associates Limited Partnership Laser Doppler flow monitor
WO1990011044A1 (en) * 1989-03-29 1990-10-04 National Research Development Corporation Blood flow determination
WO1991006244A1 (en) * 1989-10-31 1991-05-16 Gert Nilsson A system and a method for measurement and presentation of fluid flow movements, particularly the flow of blood through a body organ
US5598841A (en) * 1993-09-24 1997-02-04 Kowa Company Ltd. Blood flow measurement system

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
Medical & Biological Engineering & Computing vol 25 no 4 pp391-396: RJ Gush et al *
Optica & Laser Technology vol 20 no 6 pp309-316 Dec 1988: B Ruth: Non-contact blood flow determin... *

Also Published As

Publication number Publication date
GB2336733B (en) 2001-02-21
GB2351197A (en) 2000-12-20
GB2351197B (en) 2001-02-21
GB9909639D0 (en) 1999-06-23
GB0023213D0 (en) 2000-11-01

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Legal Events

Date Code Title Description
PCNP Patent ceased through non-payment of renewal fee

Effective date: 20121107