GB2333102A - Detection of retroviral subtypes based upon envelope specific sequence - Google Patents

Detection of retroviral subtypes based upon envelope specific sequence

Info

Publication number
GB2333102A
GB2333102A GB9826996A GB9826996A GB2333102A GB 2333102 A GB2333102 A GB 2333102A GB 9826996 A GB9826996 A GB 9826996A GB 9826996 A GB9826996 A GB 9826996A GB 2333102 A GB2333102 A GB 2333102A
Authority
GB
United Kingdom
Prior art keywords
retroviral
detection
specific sequence
subtypes based
subtypes
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
GB9826996A
Other versions
GB2333102B (en
GB9826996D0 (en
Inventor
Jonathan Paul Stoye
Robin Anthony Weiss
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Medical Research Council
Original Assignee
Medical Research Council
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9710154.7A external-priority patent/GB9710154D0/en
Application filed by Medical Research Council filed Critical Medical Research Council
Priority to GB9826996A priority Critical patent/GB2333102B/en
Publication of GB9826996D0 publication Critical patent/GB9826996D0/en
Publication of GB2333102A publication Critical patent/GB2333102A/en
Application granted granted Critical
Publication of GB2333102B publication Critical patent/GB2333102B/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • C12Q1/701—Specific hybridization probes
    • C12Q1/702—Specific hybridization probes for retroviruses
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56983—Viruses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/10022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Hematology (AREA)
  • Microbiology (AREA)
  • Urology & Nephrology (AREA)
  • Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

The present invention is based upon the finding that porcine endogenous retroviruses exist in two different subtypes, which we have termed PERV-A and PERV-B. The differences are reflected in sequence divergence in the envelope genes, and these differences may be used to provide nucleic acid and antibody probes which can distinguish between the two subtypes. This allows patterns of subtype transmission between cells, particularly porcine to human cells, to be monitored.
GB9826996A 1997-05-16 1998-05-18 Detection of retroviral subtypes based upon envelope specific sequence Expired - Fee Related GB2333102B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
GB9826996A GB2333102B (en) 1997-05-16 1998-05-18 Detection of retroviral subtypes based upon envelope specific sequence

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB9710154.7A GB9710154D0 (en) 1997-05-16 1997-05-16 Detection of retroviruses
PCT/GB1998/001428 WO1998053104A2 (en) 1997-05-16 1998-05-18 Detection of retroviral subtypes based upon envelope specific sequences
GB9826996A GB2333102B (en) 1997-05-16 1998-05-18 Detection of retroviral subtypes based upon envelope specific sequence

Publications (3)

Publication Number Publication Date
GB9826996D0 GB9826996D0 (en) 1999-02-03
GB2333102A true GB2333102A (en) 1999-07-14
GB2333102B GB2333102B (en) 2001-02-21

Family

ID=26311555

Family Applications (1)

Application Number Title Priority Date Filing Date
GB9826996A Expired - Fee Related GB2333102B (en) 1997-05-16 1998-05-18 Detection of retroviral subtypes based upon envelope specific sequence

Country Status (1)

Country Link
GB (1) GB2333102B (en)

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997021836A1 (en) * 1995-12-14 1997-06-19 The General Hospital Corporation Molecular sequence of swine retrovirus and methods of use
WO1997040167A1 (en) * 1996-04-19 1997-10-30 Q-One Biotech Ltd. Porcine retrovirus

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997021836A1 (en) * 1995-12-14 1997-06-19 The General Hospital Corporation Molecular sequence of swine retrovirus and methods of use
WO1997040167A1 (en) * 1996-04-19 1997-10-30 Q-One Biotech Ltd. Porcine retrovirus

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
1995 1 (11) PG 1100 NATURE MEDICINE, STOVE ET AL. *
1997 29(1-2)PGS 879-898 TRANSPLANTATION PROC. HOOPES ET AL *
1997 3 (3) PGS 282-286 NATURE MEDICINE, PATIENCE ET AL *
1998 389 PGS 681-682 NATURE, LE TISSIER ET AL *

Also Published As

Publication number Publication date
GB2333102B (en) 2001-02-21
GB9826996D0 (en) 1999-02-03

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Legal Events

Date Code Title Description
PCNP Patent ceased through non-payment of renewal fee

Effective date: 20080518