GB2329469B - Assays,agents,therapy and diagnosis relating to modulation of cellular DNA repair activity - Google Patents

Assays,agents,therapy and diagnosis relating to modulation of cellular DNA repair activity

Info

Publication number
GB2329469B
GB2329469B GB9820948A GB9820948A GB2329469B GB 2329469 B GB2329469 B GB 2329469B GB 9820948 A GB9820948 A GB 9820948A GB 9820948 A GB9820948 A GB 9820948A GB 2329469 B GB2329469 B GB 2329469B
Authority
GB
United Kingdom
Prior art keywords
assays
therapy
modulation
agents
dna repair
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
GB9820948A
Other versions
GB2329469A (en
GB9820948D0 (en
Inventor
Stephen Philip Jackson
Susan Elizabeth Critchlow
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Calor Group Ltd
Cancer Research Campaign Technology Ltd
Kudos Pharmaceuticals Ltd
Original Assignee
Calor Group Ltd
Cancer Research Campaign Technology Ltd
Kudos Pharmaceuticals Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9700574.8A external-priority patent/GB9700574D0/en
Priority claimed from GBGB9713131.2A external-priority patent/GB9713131D0/en
Application filed by Calor Group Ltd, Cancer Research Campaign Technology Ltd, Kudos Pharmaceuticals Ltd filed Critical Calor Group Ltd
Priority claimed from GB9800663A external-priority patent/GB2322193B/en
Publication of GB9820948D0 publication Critical patent/GB9820948D0/en
Publication of GB2329469A publication Critical patent/GB2329469A/en
Application granted granted Critical
Publication of GB2329469B publication Critical patent/GB2329469B/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5011Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing antineoplastic activity
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/25Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving enzymes not classifiable in groups C12Q1/26 - C12Q1/66
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6842Proteomic analysis of subsets of protein mixtures with reduced complexity, e.g. membrane proteins, phosphoproteins, organelle proteins
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90Enzymes; Proenzymes
    • G01N2333/9015Ligases (6)
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90Enzymes; Proenzymes
    • G01N2333/91Transferases (2.)
    • G01N2333/912Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Cell Biology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Biophysics (AREA)
  • Organic Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Toxicology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
GB9820948A 1997-01-13 1998-01-13 Assays,agents,therapy and diagnosis relating to modulation of cellular DNA repair activity Expired - Fee Related GB2329469B (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB9700574.8A GB9700574D0 (en) 1997-01-13 1997-01-13 Methods and means relating to retrotransposon and retroviral integration
GBGB9713131.2A GB9713131D0 (en) 1997-06-20 1997-06-20 Assays,therapeutic and diagnostic methods and means
GB9800663A GB2322193B (en) 1997-01-13 1998-01-13 Assays,agents,therapy and diagnosis relating to modulation of cellular dna repair activity

Publications (3)

Publication Number Publication Date
GB9820948D0 GB9820948D0 (en) 1998-11-18
GB2329469A GB2329469A (en) 1999-03-24
GB2329469B true GB2329469B (en) 1999-09-22

Family

ID=27268668

Family Applications (2)

Application Number Title Priority Date Filing Date
GB9820948A Expired - Fee Related GB2329469B (en) 1997-01-13 1998-01-13 Assays,agents,therapy and diagnosis relating to modulation of cellular DNA repair activity
GB9820952A Expired - Fee Related GB2329248B (en) 1997-01-13 1998-01-13 Assays,agents,therapy and diagnosis relating to modulation of cellular dna repair activity

Family Applications After (1)

Application Number Title Priority Date Filing Date
GB9820952A Expired - Fee Related GB2329248B (en) 1997-01-13 1998-01-13 Assays,agents,therapy and diagnosis relating to modulation of cellular dna repair activity

Country Status (1)

Country Link
GB (2) GB2329469B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2004500849A (en) * 2000-05-20 2004-01-15 キャンサー・リサーチ・テクノロジー・リミテッド Drug screening systems and assays

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
Cell (1995) 83 1079-1089 (Li et al.) *
SciSearch Abstract Acc. No. 06585135 and Mutation Research (1998) 407 (1) 1-9 (Tomkinson AE et al.) *

Also Published As

Publication number Publication date
GB9820952D0 (en) 1998-11-18
GB2329469A (en) 1999-03-24
GB2329248B (en) 1999-09-22
GB9820948D0 (en) 1998-11-18
GB2329248A (en) 1999-03-17

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Legal Events

Date Code Title Description
732E Amendments to the register in respect of changes of name or changes affecting rights (sect. 32/1977)
PCNP Patent ceased through non-payment of renewal fee

Effective date: 20100113