GB2316077A - Pyrimidine Compounds - Google Patents

Pyrimidine Compounds

Info

Publication number
GB2316077A
GB2316077A GB9720294A GB9720294A GB2316077A GB 2316077 A GB2316077 A GB 2316077A GB 9720294 A GB9720294 A GB 9720294A GB 9720294 A GB9720294 A GB 9720294A GB 2316077 A GB2316077 A GB 2316077A
Authority
GB
United Kingdom
Prior art keywords
pyrimidine compounds
synthesis
novel
compounds
iodopyrimidine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
GB9720294A
Other versions
GB2316077B (en
GB9720294D0 (en
Inventor
Robert Andrew Lewis
John William Goodby
Kenneth Johnson Toyne
Michael Hird
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
UK Secretary of State for Defence
Original Assignee
UK Secretary of State for Defence
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9506309.5A external-priority patent/GB9506309D0/en
Application filed by UK Secretary of State for Defence filed Critical UK Secretary of State for Defence
Priority to GB9720294A priority Critical patent/GB2316077B/en
Publication of GB9720294D0 publication Critical patent/GB9720294D0/en
Publication of GB2316077A publication Critical patent/GB2316077A/en
Application granted granted Critical
Publication of GB2316077B publication Critical patent/GB2316077B/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/32—One oxygen, sulfur or nitrogen atom
    • C07D239/34—One oxygen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/10—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09K—MATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FOR ELSEWHERE
    • C09K19/00—Liquid crystal materials
    • C09K19/04—Liquid crystal materials characterised by the chemical structure of the liquid crystal components, e.g. by a specific unit
    • C09K19/06—Non-steroidal liquid crystal compounds
    • C09K19/34—Non-steroidal liquid crystal compounds containing at least one heterocyclic ring
    • C09K19/3441—Non-steroidal liquid crystal compounds containing at least one heterocyclic ring having nitrogen as hetero atom
    • C09K19/345—Non-steroidal liquid crystal compounds containing at least one heterocyclic ring having nitrogen as hetero atom the heterocyclic ring being a six-membered aromatic ring containing two nitrogen atoms
    • C09K19/3458—Uncondensed pyrimidines
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09K—MATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FOR ELSEWHERE
    • C09K19/00—Liquid crystal materials
    • C09K19/04—Liquid crystal materials characterised by the chemical structure of the liquid crystal components, e.g. by a specific unit
    • C09K19/06—Non-steroidal liquid crystal compounds
    • C09K19/34—Non-steroidal liquid crystal compounds containing at least one heterocyclic ring
    • C09K19/3441—Non-steroidal liquid crystal compounds containing at least one heterocyclic ring having nitrogen as hetero atom
    • C09K19/345—Non-steroidal liquid crystal compounds containing at least one heterocyclic ring having nitrogen as hetero atom the heterocyclic ring being a six-membered aromatic ring containing two nitrogen atoms
    • C09K19/3458—Uncondensed pyrimidines
    • C09K19/3461—Pyrimidine-tolane
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09K—MATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FOR ELSEWHERE
    • C09K19/00—Liquid crystal materials
    • C09K19/04—Liquid crystal materials characterised by the chemical structure of the liquid crystal components, e.g. by a specific unit
    • C09K19/06—Non-steroidal liquid crystal compounds
    • C09K19/34—Non-steroidal liquid crystal compounds containing at least one heterocyclic ring
    • C09K19/3441—Non-steroidal liquid crystal compounds containing at least one heterocyclic ring having nitrogen as hetero atom
    • C09K19/345—Non-steroidal liquid crystal compounds containing at least one heterocyclic ring having nitrogen as hetero atom the heterocyclic ring being a six-membered aromatic ring containing two nitrogen atoms
    • C09K19/3458—Uncondensed pyrimidines
    • C09K19/3463—Pyrimidine with a carbon chain containing at least one asymmetric carbon atom, i.e. optically active pyrimidines
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09K—MATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FOR ELSEWHERE
    • C09K19/00—Liquid crystal materials
    • C09K19/04—Liquid crystal materials characterised by the chemical structure of the liquid crystal components, e.g. by a specific unit
    • C09K19/06—Non-steroidal liquid crystal compounds
    • C09K19/34—Non-steroidal liquid crystal compounds containing at least one heterocyclic ring
    • C09K19/3441—Non-steroidal liquid crystal compounds containing at least one heterocyclic ring having nitrogen as hetero atom
    • C09K19/345—Non-steroidal liquid crystal compounds containing at least one heterocyclic ring having nitrogen as hetero atom the heterocyclic ring being a six-membered aromatic ring containing two nitrogen atoms
    • C09K19/3458—Uncondensed pyrimidines
    • C09K19/3466—Pyrimidine with at least another heterocycle in the chain
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09K—MATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FOR ELSEWHERE
    • C09K19/00—Liquid crystal materials
    • C09K19/04—Liquid crystal materials characterised by the chemical structure of the liquid crystal components, e.g. by a specific unit
    • C09K19/06—Non-steroidal liquid crystal compounds
    • C09K19/34—Non-steroidal liquid crystal compounds containing at least one heterocyclic ring
    • C09K19/3491—Non-steroidal liquid crystal compounds containing at least one heterocyclic ring having sulfur as hetero atom
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09K—MATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FOR ELSEWHERE
    • C09K19/00—Liquid crystal materials
    • C09K19/52—Liquid crystal materials characterised by components which are not liquid crystals, e.g. additives with special physical aspect: solvents, solid particles
    • C09K19/58—Dopants or charge transfer agents
    • C09K19/582—Electrically active dopants, e.g. charge transfer agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Materials Engineering (AREA)
  • Liquid Crystal Substances (AREA)

Abstract

The synthesis of novel compound (I) is described: 5-bromo-2-iodopyrimidine may be used for the synthesis of a range of chemical compounds both known and novel. The synthesis of a number of novel liquid crystalline compounds is described.
GB9720294A 1995-03-28 1996-03-28 Pyrimidine Compounds Expired - Fee Related GB2316077B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
GB9720294A GB2316077B (en) 1995-03-28 1996-03-28 Pyrimidine Compounds

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB9506309.5A GB9506309D0 (en) 1995-03-28 1995-03-28 Pyrimidine compounds
GB9720294A GB2316077B (en) 1995-03-28 1996-03-28 Pyrimidine Compounds
PCT/GB1996/000866 WO1996030344A2 (en) 1995-03-28 1996-03-28 Pyrimidine compounds

Publications (3)

Publication Number Publication Date
GB9720294D0 GB9720294D0 (en) 1997-11-26
GB2316077A true GB2316077A (en) 1998-02-18
GB2316077B GB2316077B (en) 1999-09-08

Family

ID=26306761

Family Applications (1)

Application Number Title Priority Date Filing Date
GB9720294A Expired - Fee Related GB2316077B (en) 1995-03-28 1996-03-28 Pyrimidine Compounds

Country Status (1)

Country Link
GB (1) GB2316077B (en)

Citations (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0225195A1 (en) * 1985-12-04 1987-06-10 Ajinomoto Co., Inc. Phenylpyrimidine-based compounds and liquid crystal composition containing the same
EP0255962A2 (en) * 1986-08-08 1988-02-17 Canon Kabushiki Kaisha Optically active mesomorphic compound
EP0278665A2 (en) * 1987-02-02 1988-08-17 Chisso Corporation 2-Substituted-alkyl ether and liquid crystal composition
WO1988007523A1 (en) * 1987-03-27 1988-10-06 MERCK Patent Gesellschaft mit beschränkter Haftung Acetylene derivatives as components of liquid crystal phases
EP0332025A1 (en) * 1988-03-10 1989-09-13 MERCK PATENT GmbH Chiral derivatives of 1,2-difluorobenzenes
EP0332024A1 (en) * 1988-03-10 1989-09-13 MERCK PATENT GmbH Heterocyclic derivatives of 1,2-difluorobenzene
WO1990013611A2 (en) * 1989-05-11 1990-11-15 MERCK Patent Gesellschaft mit beschränkter Haftung Optically active compounds and liquid crystal phase
WO1990015116A1 (en) * 1989-06-10 1990-12-13 MERCK Patent Gesellschaft mit beschränkter Haftung Fluorophenyl pyrimidines
EP0438811A2 (en) * 1990-01-24 1991-07-31 Hoechst Aktiengesellschaft Esters of 3-halogeno- or 3-cyano-substituted 2-methylalkanecarboxylic acids and their use as doping agents in liquid-crystalline compositions
JPH05255151A (en) * 1991-11-20 1993-10-05 Asahi Glass Co Ltd Tetrafluorobenzene derivative compound and liquid crystal composition
DE4220065A1 (en) * 1992-06-19 1993-12-23 Merck Patent Gmbh Linear poly:cyclic pyrimidine and 2-phenyl-5-bromo-pyrimidine cpds. - aare useful in liquid crystal medium and as intermediates
EP0611119A2 (en) * 1993-02-10 1994-08-17 Canon Kabushiki Kaisha Optically active compound, liquid crystal composition containing same, liquid crystal device, display apparatus and display method
WO1996001246A1 (en) * 1994-07-01 1996-01-18 The Secretary Of State For Defence Liquid crystal compounds, mixtures and devices

Patent Citations (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0225195A1 (en) * 1985-12-04 1987-06-10 Ajinomoto Co., Inc. Phenylpyrimidine-based compounds and liquid crystal composition containing the same
EP0255962A2 (en) * 1986-08-08 1988-02-17 Canon Kabushiki Kaisha Optically active mesomorphic compound
EP0278665A2 (en) * 1987-02-02 1988-08-17 Chisso Corporation 2-Substituted-alkyl ether and liquid crystal composition
WO1988007523A1 (en) * 1987-03-27 1988-10-06 MERCK Patent Gesellschaft mit beschränkter Haftung Acetylene derivatives as components of liquid crystal phases
EP0332025A1 (en) * 1988-03-10 1989-09-13 MERCK PATENT GmbH Chiral derivatives of 1,2-difluorobenzenes
EP0332024A1 (en) * 1988-03-10 1989-09-13 MERCK PATENT GmbH Heterocyclic derivatives of 1,2-difluorobenzene
WO1990013611A2 (en) * 1989-05-11 1990-11-15 MERCK Patent Gesellschaft mit beschränkter Haftung Optically active compounds and liquid crystal phase
WO1990015116A1 (en) * 1989-06-10 1990-12-13 MERCK Patent Gesellschaft mit beschränkter Haftung Fluorophenyl pyrimidines
EP0438811A2 (en) * 1990-01-24 1991-07-31 Hoechst Aktiengesellschaft Esters of 3-halogeno- or 3-cyano-substituted 2-methylalkanecarboxylic acids and their use as doping agents in liquid-crystalline compositions
JPH05255151A (en) * 1991-11-20 1993-10-05 Asahi Glass Co Ltd Tetrafluorobenzene derivative compound and liquid crystal composition
DE4220065A1 (en) * 1992-06-19 1993-12-23 Merck Patent Gmbh Linear poly:cyclic pyrimidine and 2-phenyl-5-bromo-pyrimidine cpds. - aare useful in liquid crystal medium and as intermediates
EP0611119A2 (en) * 1993-02-10 1994-08-17 Canon Kabushiki Kaisha Optically active compound, liquid crystal composition containing same, liquid crystal device, display apparatus and display method
WO1996001246A1 (en) * 1994-07-01 1996-01-18 The Secretary Of State For Defence Liquid crystal compounds, mixtures and devices

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
Chem. Pharm. Bull., 1978, Vol. 26(12), pages 3843-3850 *
Chemical Abstracts, 120:232308 & JP 05 255 151 A *
J. Chem. Soc., Perkin Trans. 1, 1977, Vol. (6), pages 621-624 *
Liq. Cryst., 1993, Vol. 14(3), pages 741-761 *

Also Published As

Publication number Publication date
GB2316077B (en) 1999-09-08
GB9720294D0 (en) 1997-11-26

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Legal Events

Date Code Title Description
732E Amendments to the register in respect of changes of name or changes affecting rights (sect. 32/1977)
PCNP Patent ceased through non-payment of renewal fee

Effective date: 20040328

PCNP Patent ceased through non-payment of renewal fee

Effective date: 20040328