GB2294464A - Phanylalanine-free protien and dna coding therefor - Google Patents

Phanylalanine-free protien and dna coding therefor

Info

Publication number
GB2294464A
GB2294464A GB9523511A GB9523511A GB2294464A GB 2294464 A GB2294464 A GB 2294464A GB 9523511 A GB9523511 A GB 9523511A GB 9523511 A GB9523511 A GB 9523511A GB 2294464 A GB2294464 A GB 2294464A
Authority
GB
United Kingdom
Prior art keywords
phanylalanine
protien
free
dna coding
coding therefor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
GB9523511A
Other versions
GB9523511D0 (en
GB2294464A8 (en
GB2294464B (en
Inventor
Noel Gordon Carr
Nicholas Harold Mann
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Warwick
Original Assignee
University of Warwick
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB939310472A external-priority patent/GB9310472D0/en
Application filed by University of Warwick filed Critical University of Warwick
Priority to GB9523511A priority Critical patent/GB2294464B/en
Publication of GB9523511D0 publication Critical patent/GB9523511D0/en
Publication of GB2294464A publication Critical patent/GB2294464A/en
Publication of GB2294464A8 publication Critical patent/GB2294464A8/en
Application granted granted Critical
Publication of GB2294464B publication Critical patent/GB2294464B/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/76—Albumins
    • C07K14/77—Ovalbumin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4732—Casein

Abstract

A DNA molecule coding for a food protein, such as ovalbumin or casein, modified so that the codons for phenylalanine have been omitted or replaced by codons for one or more other metabolisable amino acids. Also a modified edible protein coded for by such a DNA molecule. Such modified proteins are useful in the nutrition of patients suffering from phenylketonuria.
GB9523511A 1993-05-20 1994-05-16 Phenylalanine-free protein and DNA coding therefor Expired - Fee Related GB2294464B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
GB9523511A GB2294464B (en) 1993-05-20 1994-05-16 Phenylalanine-free protein and DNA coding therefor

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB939310472A GB9310472D0 (en) 1993-05-20 1993-05-20 Phenylalanine-free protein and dna coding thereof
PCT/GB1994/001046 WO1994028126A2 (en) 1993-05-20 1994-05-16 Phenylalanine-free protein and dna coding therefor
GB9523511A GB2294464B (en) 1993-05-20 1994-05-16 Phenylalanine-free protein and DNA coding therefor

Publications (4)

Publication Number Publication Date
GB9523511D0 GB9523511D0 (en) 1996-01-17
GB2294464A true GB2294464A (en) 1996-05-01
GB2294464A8 GB2294464A8 (en) 1997-04-01
GB2294464B GB2294464B (en) 1998-03-11

Family

ID=26302923

Family Applications (1)

Application Number Title Priority Date Filing Date
GB9523511A Expired - Fee Related GB2294464B (en) 1993-05-20 1994-05-16 Phenylalanine-free protein and DNA coding therefor

Country Status (1)

Country Link
GB (1) GB2294464B (en)

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4016147A (en) * 1975-01-16 1977-04-05 Fuji Oil Company, Ltd. Method for preparation of low-phenylalanine plastein
GB2068969A (en) * 1980-02-05 1981-08-19 Upjohn Co Gene expression
JPH04126051A (en) * 1990-09-18 1992-04-27 Snow Brand Milk Prod Co Ltd Nutritional preparation for patient suffering from phenylketonuria
WO1993004171A1 (en) * 1991-08-19 1993-03-04 Symbicom Aktiebolag Human beta-casein, process for producing it and use thereof

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0285675A1 (en) * 1987-02-06 1988-10-12 BIOSYNTECH Biochemische Synthesetechnik GmbH Synthetic DNA cassette, encoding an artificial protein, and its expression

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4016147A (en) * 1975-01-16 1977-04-05 Fuji Oil Company, Ltd. Method for preparation of low-phenylalanine plastein
GB2068969A (en) * 1980-02-05 1981-08-19 Upjohn Co Gene expression
JPH04126051A (en) * 1990-09-18 1992-04-27 Snow Brand Milk Prod Co Ltd Nutritional preparation for patient suffering from phenylketonuria
WO1993004171A1 (en) * 1991-08-19 1993-03-04 Symbicom Aktiebolag Human beta-casein, process for producing it and use thereof

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
J.Dairy Sci. 1988,71(10),2640-2654 *
J.Dairy Sci. 1989,72(10),2464-2473 *
Patent Abstracts of Japan, 18.08.92,16(387),Abs.C-0975 & JP 04 126051 A *
Proc.6th Int.Conf.Food Sci.Technol. 1983,3,3-4 *

Also Published As

Publication number Publication date
GB9523511D0 (en) 1996-01-17
GB2294464A8 (en) 1997-04-01
GB2294464B (en) 1998-03-11

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Legal Events

Date Code Title Description
732E Amendments to the register in respect of changes of name or changes affecting rights (sect. 32/1977)
732E Amendments to the register in respect of changes of name or changes affecting rights (sect. 32/1977)
PCNP Patent ceased through non-payment of renewal fee

Effective date: 20020516