GB2284763B - Pharmaceutical capsule containing an organic nitrate and a salicylate - Google Patents

Pharmaceutical capsule containing an organic nitrate and a salicylate

Info

Publication number
GB2284763B
GB2284763B GB9501985A GB9501985A GB2284763B GB 2284763 B GB2284763 B GB 2284763B GB 9501985 A GB9501985 A GB 9501985A GB 9501985 A GB9501985 A GB 9501985A GB 2284763 B GB2284763 B GB 2284763B
Authority
GB
United Kingdom
Prior art keywords
salicylate
capsule containing
organic nitrate
pharmaceutical capsule
pharmaceutical
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
GB9501985A
Other versions
GB2284763A (en
GB9501985D0 (en
Inventor
William Byrne
Andrew Rynne
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cal International Ltd
Original Assignee
Cal International Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cal International Ltd filed Critical Cal International Ltd
Priority claimed from GB9501785A external-priority patent/GB2284350B/en
Publication of GB9501985D0 publication Critical patent/GB9501985D0/en
Publication of GB2284763A publication Critical patent/GB2284763A/en
Application granted granted Critical
Publication of GB2284763B publication Critical patent/GB2284763B/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/60—Salicylic acid; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/60—Salicylic acid; Derivatives thereof
    • A61K31/618—Salicylic acid; Derivatives thereof having the carboxyl group in position 1 esterified, e.g. salsalate
    • A61K31/621—Salicylic acid; Derivatives thereof having the carboxyl group in position 1 esterified, e.g. salsalate having the hydroxy group in position 2 esterified, e.g. benorylate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4808—Preparations in capsules, e.g. of gelatin, of chocolate characterised by the form of the capsule or the structure of the filling; Capsules containing small tablets; Capsules with outer layer for immediate drug release
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5084—Mixtures of one or more drugs in different galenical forms, at least one of which being granules, microcapsules or (coated) microparticles according to A61K9/16 or A61K9/50, e.g. for obtaining a specific release pattern or for combining different drugs
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C203/00—Esters of nitric or nitrous acid
    • C07C203/02—Esters of nitric acid
    • C07C203/04—Esters of nitric acid having nitrate groups bound to acyclic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C203/00—Esters of nitric or nitrous acid
    • C07C203/02—Esters of nitric acid
    • C07C203/04—Esters of nitric acid having nitrate groups bound to acyclic carbon atoms
    • C07C203/06—Glycerol trinitrate

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
GB9501985A 1992-07-30 1993-07-26 Pharmaceutical capsule containing an organic nitrate and a salicylate Expired - Fee Related GB2284763B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IE922474 1992-07-30
GB9501785A GB2284350B (en) 1992-07-30 1993-07-26 Pharmaceutical compositions comprising esters of organic nitrates and a salicylate

Publications (3)

Publication Number Publication Date
GB9501985D0 GB9501985D0 (en) 1995-03-22
GB2284763A GB2284763A (en) 1995-06-21
GB2284763B true GB2284763B (en) 1996-08-28

Family

ID=26306398

Family Applications (1)

Application Number Title Priority Date Filing Date
GB9501985A Expired - Fee Related GB2284763B (en) 1992-07-30 1993-07-26 Pharmaceutical capsule containing an organic nitrate and a salicylate

Country Status (1)

Country Link
GB (1) GB2284763B (en)

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0449426A1 (en) * 1990-02-26 1991-10-02 Byrne Rynne Holdings Limited A pharmaceutical composition

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0449426A1 (en) * 1990-02-26 1991-10-02 Byrne Rynne Holdings Limited A pharmaceutical composition

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
European Heart Journal Vol.12, Suppl. A,pages 2 to 4 (1991) *

Also Published As

Publication number Publication date
GB2284763A (en) 1995-06-21
GB9501985D0 (en) 1995-03-22

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Legal Events

Date Code Title Description
PCNP Patent ceased through non-payment of renewal fee

Effective date: 20080726