GB2252562A - Cell culture products - Google Patents

Cell culture products

Info

Publication number
GB2252562A
GB2252562A GB9205228A GB9205228A GB2252562A GB 2252562 A GB2252562 A GB 2252562A GB 9205228 A GB9205228 A GB 9205228A GB 9205228 A GB9205228 A GB 9205228A GB 2252562 A GB2252562 A GB 2252562A
Authority
GB
United Kingdom
Prior art keywords
substrate
mammalian cells
cytotoxic
hydrophobic
inhibiting
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
GB9205228A
Other versions
GB9205228D0 (en
GB2252562B (en
Inventor
Yvonne Margaret Barlow
Stephen Michael Lang
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Smith and Nephew PLC
Original Assignee
Smith and Nephew PLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smith and Nephew PLC filed Critical Smith and Nephew PLC
Publication of GB9205228D0 publication Critical patent/GB9205228D0/en
Publication of GB2252562A publication Critical patent/GB2252562A/en
Application granted granted Critical
Publication of GB2252562B publication Critical patent/GB2252562B/en
Anticipated expiration legal-status Critical
Revoked legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/34—Internal compartments or partitions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/60—Materials for use in artificial skin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/02—Form or structure of the vessel
    • C12M23/08—Flask, bottle or test tube
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M25/00—Means for supporting, enclosing or fixing the microorganisms, e.g. immunocoatings
    • C12M25/02—Membranes; Filters
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0068—General culture methods using substrates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00—Supports or coatings for cell culture, characterised by material
    • C12N2533/30—Synthetic polymers

Abstract

A conformable wound dressing is described which comprises a layer of cultured mammalian cells anchored to one surface of a substrate comprising a film of synthetic polymer of which substrate is hydrophobic, non-inhibiting to cell growth and non-cytotoxic. Also described is a system for a manufacture of wound dressings which system composes a substrate for culturing anchorage dependent mammalian cells and means for monitoring a culture medium in contact with said substrate wherein said substrate is a conformable film of a synthetic polymeric material which is hydrophobic, non-inhibiting to cell growth and non-cytotoxic. Various alternative embodiments of the wound dressing and the system are described. A method for treating wounds using the dressing or system of the invention together with a method for the in vitro cultivation of anchorage dependent mammalian cells are also described.
GB9205228A 1990-03-05 1992-03-11 Wound dressing comprising cultured cells Revoked GB2252562B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB909004911A GB9004911D0 (en) 1990-03-05 1990-03-05 Cell culture products
PCT/GB1991/000329 WO1991013638A1 (en) 1990-03-05 1991-03-04 Cell culture products

Publications (3)

Publication Number Publication Date
GB9205228D0 GB9205228D0 (en) 1992-05-27
GB2252562A true GB2252562A (en) 1992-08-12
GB2252562B GB2252562B (en) 1994-04-20

Family

ID=10672028

Family Applications (2)

Application Number Title Priority Date Filing Date
GB909004911A Pending GB9004911D0 (en) 1990-03-05 1990-03-05 Cell culture products
GB9205228A Revoked GB2252562B (en) 1990-03-05 1992-03-11 Wound dressing comprising cultured cells

Family Applications Before (1)

Application Number Title Priority Date Filing Date
GB909004911A Pending GB9004911D0 (en) 1990-03-05 1990-03-05 Cell culture products

Country Status (11)

Country Link
EP (2) EP0518920B1 (en)
JP (1) JPH05504497A (en)
AT (1) ATE139685T1 (en)
AU (1) AU649656B2 (en)
CA (1) CA2065432A1 (en)
DE (1) DE69120527T2 (en)
DK (1) DK0518920T3 (en)
ES (1) ES2089195T3 (en)
GB (2) GB9004911D0 (en)
WO (1) WO1991013638A1 (en)
ZA (1) ZA911598B (en)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9004911D0 (en) 1990-03-05 1990-05-02 Smith & Nephew Cell culture products
WO1993024627A1 (en) * 1992-06-03 1993-12-09 Case Western Reserve University Bandage for continuous application of biologicals
CA2163264A1 (en) * 1993-06-02 1994-12-08 Richard L. Eckert Bandage for continuous application of biologicals
DE4426315C1 (en) * 1994-07-25 1996-03-21 Gore W L & Ass Gmbh Membrane for the regeneration of body tissues and use of the membrane as a wound covering and skin replacement
US5518925A (en) * 1995-06-06 1996-05-21 Becton Dickinson Co Culture slide assembly
US5605813A (en) * 1995-06-06 1997-02-25 Becton, Dickinson And Company Culture slide assembly
US5618731A (en) * 1995-06-06 1997-04-08 Becton, Dickinson And Company Culture slide assembly
GB9516556D0 (en) * 1995-08-12 1995-10-11 Smith & Nephew Cell culture laminate
WO1997026023A1 (en) * 1996-01-19 1997-07-24 Eth, Eidgenössische Technische Hochschule Zürich Wound dressing and apparatus
WO1998013076A1 (en) * 1996-09-24 1998-04-02 Brigham And Women's Hospital Cultured cell-seeded fibrous lattice for tissue replacement
GB9625301D0 (en) * 1996-12-05 1997-01-22 Smith & Nephew Cell-culture system
WO1998027195A1 (en) * 1996-12-18 1998-06-25 Roche Diagnostics Gmbh Receptacle for cell cultures and use of multiple dishes for culturing antitumour cells
JP4153070B2 (en) * 1998-01-21 2008-09-17 日東電工株式会社 Base material for patch, medical patch made using the same, and emergency bandage
CA2295244C (en) * 1999-01-14 2005-07-05 Masayoshi Kuniya Medical adhesive dressing and first-aid adhesive tape
US6210704B1 (en) 1999-01-14 2001-04-03 Nitto Denko Corporation Medical adhesive dressing and first-aid adhesive tape
EP2082030A2 (en) 2006-10-20 2009-07-29 Keracure, Inc. Devices with cells cultured on flexible supports
CN101601858B (en) 2009-05-27 2012-09-19 上海交通大学 Application of midkine protein and medical device containing protein
JP5866983B2 (en) * 2011-11-08 2016-02-24 大日本印刷株式会社 Cell culture vessel
KR101335176B1 (en) * 2011-12-12 2013-11-29 테고사이언스 (주) Wound Dressing
EP2854824A1 (en) 2012-05-25 2015-04-08 Boehringer Ingelheim International GmbH Use of keratinocytes as a biologically active substance in the treatment of wounds, such as diabetic wounds, optionally in combination with a dpp-4 inhibitor
US9790465B2 (en) 2013-04-30 2017-10-17 Corning Incorporated Spheroid cell culture well article and methods thereof
KR102470508B1 (en) 2014-10-29 2022-11-24 코닝 인코포레이티드 Perfusion bioreactor platform
JP7245222B2 (en) 2017-07-14 2023-03-23 コーニング インコーポレイテッド 3D cell culture vessel for manual or automatic medium exchange
US11857970B2 (en) 2017-07-14 2024-01-02 Corning Incorporated Cell culture vessel
JP7197557B2 (en) 2017-07-14 2022-12-27 コーニング インコーポレイテッド Cell culture vessel with porous support
EP3652292A1 (en) 2017-07-14 2020-05-20 Corning Incorporated Cell culture vessel for 3d culture and methods of culturing 3d cells
WO2020013845A1 (en) * 2018-07-13 2020-01-16 Corning Incorporated Cell culture vessels with stabilizer devices
EP3649227A1 (en) 2018-07-13 2020-05-13 Corning Incorporated Fluidic devices including microplates with interconnected wells
US11912968B2 (en) 2018-07-13 2024-02-27 Corning Incorporated Microcavity dishes with sidewall including liquid medium delivery surface

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0092302A2 (en) * 1982-04-16 1983-10-26 Becton Dickinson and Company Chemically specific surfaces for influencing cell activity during culture
WO1988008448A2 (en) * 1987-04-22 1988-11-03 Michael Bay Cell culture processes, materials and products
WO1989003228A1 (en) * 1987-10-14 1989-04-20 Board Of Regents, The University Of Texas System Epidermal graft system
WO1990000595A1 (en) * 1988-07-05 1990-01-25 Banes Albert J Floating cell culture device and method

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL267226A (en) 1960-07-19
GB1055963A (en) 1963-08-27 1967-01-25 Smith & Nephew Improvements in and relating to open work materials in sheet form
GB8328279D0 (en) 1983-10-22 1983-11-23 Smith & Nephew Res Polymer blend films
IL75554A (en) * 1985-06-18 1993-01-14 Yeda Res & Dev Matrix for cell cultivation in vitro
ATE77408T1 (en) * 1987-04-03 1992-07-15 Yeda Res & Dev CELL CULTURE CARRIER.
CA1315491C (en) 1989-06-28 1993-04-06 Desmond Maurice Kendall Sanitary fixtures
GB9004911D0 (en) 1990-03-05 1990-05-02 Smith & Nephew Cell culture products

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0092302A2 (en) * 1982-04-16 1983-10-26 Becton Dickinson and Company Chemically specific surfaces for influencing cell activity during culture
WO1988008448A2 (en) * 1987-04-22 1988-11-03 Michael Bay Cell culture processes, materials and products
WO1989003228A1 (en) * 1987-10-14 1989-04-20 Board Of Regents, The University Of Texas System Epidermal graft system
WO1990000595A1 (en) * 1988-07-05 1990-01-25 Banes Albert J Floating cell culture device and method

Also Published As

Publication number Publication date
EP0518920B1 (en) 1996-06-26
GB9205228D0 (en) 1992-05-27
JPH05504497A (en) 1993-07-15
EP0681846A2 (en) 1995-11-15
ES2089195T3 (en) 1996-10-01
ATE139685T1 (en) 1996-07-15
DE69120527D1 (en) 1996-08-01
DE69120527T2 (en) 1997-01-16
DK0518920T3 (en) 1996-08-05
ZA911598B (en) 1991-11-27
EP0681846A3 (en) 1996-03-27
CA2065432A1 (en) 1991-09-06
AU649656B2 (en) 1994-06-02
WO1991013638A1 (en) 1991-09-19
GB2252562B (en) 1994-04-20
GB9004911D0 (en) 1990-05-02
EP0518920A1 (en) 1992-12-23
AU7348591A (en) 1991-10-10

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Legal Events

Date Code Title Description
773K Patent revoked under sect. 73(2)/1977