GB2251080A - Measuring and treatment tool incorporating broad band stripline aerials and useful in medical technology - Google Patents

Measuring and treatment tool incorporating broad band stripline aerials and useful in medical technology Download PDF

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Publication number
GB2251080A
GB2251080A GB9126811A GB9126811A GB2251080A GB 2251080 A GB2251080 A GB 2251080A GB 9126811 A GB9126811 A GB 9126811A GB 9126811 A GB9126811 A GB 9126811A GB 2251080 A GB2251080 A GB 2251080A
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recited
strip
electromagnetic energy
stripline
ground plane
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GB9126811D0 (en
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Bibhas R De
Michael A Nelson
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Chevron USA Inc
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Chevron Research and Technology Co
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/05Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves 
    • A61B5/0507Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves  using microwaves or terahertz waves
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/05Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves 
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/40Applying electric fields by inductive or capacitive coupling ; Applying radio-frequency signals
    • A61N1/403Applying electric fields by inductive or capacitive coupling ; Applying radio-frequency signals for thermotherapy, e.g. hyperthermia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/02Radiation therapy using microwaves
    • A61N5/04Radiators for near-field treatment

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Radiology & Medical Imaging (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pathology (AREA)
  • Biophysics (AREA)
  • Surgery (AREA)
  • Medical Informatics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Radiation-Therapy Devices (AREA)
  • Measurement And Recording Of Electrical Phenomena And Electrical Characteristics Of The Living Body (AREA)

Abstract

The tool, for determining the nature of fluid in mammal tissue or cancer therapy by hyperthermia transmits, and optionally receives electromagnetic radiation over a broad band of 2KHz - 1GHz and can determine resistivity and dielectric constant. It incorporates at least one transmitting and receiving antenna. Each antenna comprises a coaxial cable 151 connected to stripline adapter 153, which is connected to a stripline (155) having a metallic central strip (159). A strip face 161 is bent at approximately right angles, and has a length that is compatible with the desired frequency coverage. A ground plane 165 extends from the stripline adapter to the right angle bend, and a dielectric 167 fills the space between the centre strip and the ground plane. An enclosure comprising four metallic walls 181 surrounds the stripline, and is in electrical contact with the ground plane and the stripline adapter and a lossless, non-conducting material fills the enclosure. The antennae are positioned so that the strip face lies flush with the tool face, to permit electromagnetic energy to be transmitted into and out of the material to be analyzed. Amplitude and phase of the received signal are monitored. <IMAGE>

Description

22510,30 01 02 03 04 05 06 07 08 09 10 11 12 13 14 15 16 17 is 19 20 21 22
23 24 25 26 27 28 29 30 31 32 33 34 METHOD AND APPARATUS FOR BROADBAND ELECTROMAGNETIC ENERGY COUPLING The present invention relates generally to the electromagnetic coupling and analysis. More specifically, this invention provides an antenna which can combine the functions of various resistivity and dielectric constant devices into a single tool, capable of operating over a wide range of frequencies. It is particularly useful In the field of medical technology.
in the field of medical technology, it is well knmm that electromagnetic energy is useful in various types of diagnoses and treatments. For example, recent statistics show that pulmonary and cardiopulmonary diseases are responsible for more than three million hospital admissions and 30,000 deaths every year in the United States. Pulmonary abnormalities are virtually"always associated with changes in lung water content or distribution. Most workers agree that there is no single, nondestructive method available to detect accurately early changes in lung water content.
For a clinically useful technique, it is desirable to detect early changes in both the extravascular lung water# which strongly reflects most pulmonary abnormalities, aM the intravascular compartment. Recently, the use of the electromagnetic methods to detect changes in lung water content have shown promising initial results, particularly for detecting small variations in water content.
Particularly at microwave frequencies, changes in the dielectric properties of tissue are closely related to the amount of water present. Electromagnetic techniques, therefore, basically utilize changes in the permittivity and conductivity of the lung region to dtect changes In lung water content. This method has the advantage of using highly penetrating electromagnetic signals rather than ultrasonic signals which are both highly attenuated and dispersed in the lung. Furthermore, electromagnetic techniques have the potential for continuous monitoring of patients in intensive care units, such as those with heart failure or extensive burns.
01 02 03 04 05 06 07 08 09 10 11 12 13 14 U.S. Patent No. 4,240,445 issued to Iskander et al. and is incorporated herein by reference for all purposes. Iskander 16 teaches a method of coupling electromagnetic energy into a 17 material such as tissue, to measure water content.
18 Measuring lung water content is an especially useful 19 application. However, Iskander's device is so large that only a few antennas can be place on the chest, and the 21 antenna cannot be described as a point source. Also,. the 22 electric field vanishes at some distance from the antenna,
23 as the electric fields in the two parallel slots are
24 oppositely directed. Furthermore. a resistor is included in the antenna, which dissipates much of the electromagnetic 26 energy in the antenna itself and introduces a limitation in 27 the power handling capability of the antenna. Additional 28 prior work includest M. F. Iskander and C. H. Durney 29 (1980): Electromagnetic Techniques for medical Diagnosis:
A Revieww, Proceedings of IZEE, vol. 68, no. 1. and 31 M. 7. Iskander et al (1982): "Two-dimensional Technique to 32 Calculate the EM Power Deposition Pattern in the Human 33 Body", Journal of Microwave Power, vol. 17, no. 3. There is 34 thus a need for a device that is compact enough to permit placing of many antennas forming an array on a chest to obtain a well- defined image of the chest cavity, a device that has an antenna.that can be mathematically described as a point source, and one which does not suffer from cancellation of the electric field at a certain distance.
01 02 03 04 05 06 07 08 09 10 11 12 13 14 15 Schwarzenberg, Munich, F.R.G. , 1980 and Dethylefsent L.A. 16 (Editor), "The Third International Symposiumt Cancer 17 Therapy by Hyperthermia, Drugs and Radiation, Colorado State 18 University, Ft. Collins, U.S.A., 1980.) 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 A dielectric transmitting and measuring device can also be used to heat an interior portion of a mammalian body to destroy or reduce the size of tumors. Tumor reduction therapy, or cancer therapy by hyperthermia, combined with radiation or drugs is known in the art to either stop or slow down the growth of cancer cells, or cause the death of the cancer cells. (See, for example, Streffer, C., 'Cancer Therapy by Hyperthermia, and Radiation", Urban and one such device is disclosed by J. Scheiblich et al. 0Radiofrequency- Induced Hyperthermia in the ProstaW, Journal of,Microwave Power, vol. 17, no. 3, 1982p Ottawa# Canada. Scheiblich et alto device works only at a single frequency.
A propagating electromagnetic wave has two fundamental characteristics, amplitude and phase. By comparing the amplitude and phase of an electromagnetic wave as It passes receivers, propagation characteristics of the probed medium may be studied. measurement of these two characteristics may be used to determine the dielectric constant and the conductivity of the media through which the wave is propagated.
However, no one tool in the prior art is capable of probing or coupling energy into a material over a broad band of frequencies. It is therefore advantageous to extend the frequency range.
01 02 03 04 05 06 07 08 09 10 11 12 13 14 is 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 A measuring or electromagnetic coupling tool, having a tool 32 face. also has a novel transmitting antenna and a novel 33 receiving antenna. Electromagnetic energy is transmitted to 34 a transmitting antenna. A stripline adapter permits the The largest hurdle to developing such a broadband dielectric tool has been the lack of a suitable broadband antenna that can couple electromagnetic energy to and from a material, and that is compact enough to fit within the confines of a tool.
The prior work is limited in the attempts at electromagnetic coupling, analysis, and treatment, in that no suitable single antenna element has been designed which can couple electromagnetic energy into a material, such as mammal tissue, over a broad range of frequencies, that is also sufficiently compact and is capable of handling high power levels. There is therefore a need for a device and a method for use in such broadband applications.
The present invention is surprisingly successful in providing a method and apparatus for combining the functions of various conductivity and dielectric constant devices and electromagnetic energy coupling devices into a single devicer capable of operating over a wide range of frequencies. It is especially useful in medical technology applications.
01 energy to flow to a stripline having a metallic central strip. A strip face of the central strip Is bent at approximately right angles, and has a height that is compatible with desired frequency coverage.
02 03 04 05 06 07 08 09 10 11 12 13 14 15 16 17 18 19 An enclosure surrounding the stripline is comprised of four 20 metallic walls which are positioned in electrical contact 21 with the ground plane and the stripline adapter, so that the 22 strip face is nearly centered in the opening created by the 23 walls and the ground plane.
24 25 26 27 28 29 30 31 32 33 34 A ground plane extends from the stripline adapter to the right angle bend, so that a distal end of the central strip extends away from it, and a void is created between the center strip and the ground plane.
A dielectric is positioned to nearly fill the void. The dielectric is comprised of a material having a very high dielectric constant and a very low energy loss. The transmitting antenna is positioned so that the ground plane is fixedly connected to the measuring tool, and the strip face lies flush with the tool face, so that electromagnetic energy can be transmitted into the material to be analyzed.
A loss-less,, non-conducting material fills in any remaining open space in-the enclosure, so that the non-conducting material forms an additional wall that is really flat with the strip face.
A receiving antenna is comprised in essentially the same manner as the transmitting antenna, and is positioned in the tool so that it can receive the electromagnetic energy which has traveled through the material being probed. A means for 01 02 03 04 05 06 07 08 09 10 11 12 13 14 is 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 monitoring the received energy detects the phase and the amplitude.
In another embodiment of this invention, broadband measurements are taken to determine the quantity of a fluid in a material, such as water in a lung.
It is one object of this invention that electromagnetic energy is transmitted and received over a wide frequency range, specifically from a few KHz to a few GEz. A commonly used frequency range is from 2 KHz to 4 GHz.
The tool may further comprise a pad, which substantially conforms to the surface of the mammal tissue, and holds the antennas. At least one transmitting antenna is necessary. No receiving antenna is necessary, although a plurality of each is often desirable.
The above and other embodiments, objects, advantages, and features of the invention will become more readily apparent from the following detailed description of the invention, which is provided in connection with the accompanying drawings.
Figure 1 in a schematic, sectional view of the inventive device positioned adjacent to mammal tissue.
Figure 2 shows a top, front, and side view of the novel transmitting antenna.
Figure 2A is the same view as Figure 2, further illustrating the enclosing metallic walls.
1 01 Figure 3 02 03 shows an antenna mounted on a tool face.
Figure 4 shows three graphs of transmission and return loss as a function of frequency.
04 05 06 07 08 09 Figure 6 shows four graphs of time-domain transmission 10 measurements at various distances from a metal reflector plate in a brine.
Figure 5 is a graph of transmission and return loss as a function of frequency, for low frequencies.
11 12 13 14 is 16 17 is 19 20 21 22 Referring to the drawings, a first embodiment of the 23 inventive broadband tool 101 is shown in Figure 1, 24 positioned around a portion of a mammal body such as a chest 2S cavity 103. A means such as a belt mount 109 positions tool 26 face 111 near the mammal skin 104, such that transmitting 27 antennas such as T1 and T2 and receiving antennas such as R1 28 and R2 are positioned touching the skin surface of 104. The 29 tool face 111 is defined as the surface of the belt mount 109 containing the aperture plane of the antennas, and 31 is preferably a continuous metallic surface. The belt 32 mount 109 may be made of any suitable flexible material that 33 can be strapped around the portion of interest of the mammal 34 In accordance with the present invention, a new improved method and apparatus for coupling electromagnetic energy into a material for determining the nature of various materials and the fluids contained therein and to induce hyperthermia, using a broadband measuring apparatus, has been developed.
body. A conducting compound such as a conducting grease may be applied at the interface 113 between the tool face ill and the skin surface 104 to improve coupling between the antennas and the chest cavity 103.
01 02 03 04 05 06 07 08 09 10 11 12 13 An analysis of the chest cavity 103, for example, can be 14 done by a dielectric imaging of the cavity. This is done by 15 transmitting electromagnetic energy at a suitable frequency 16 across the chest cavity 103 from a transmitting antenna such 17 as Tl, and receiving this energy at a receiving antenna such 18 as Rn. In this way the phase and the amplitude of the 19 propagated electromagnetic wave for the path TlRn (shown in 21 22 23 24 25 26 27 28 29 30 31 32 31 34 The region of thi mammal body to be investigated may not be electrically homogeneous. in the chest cavity 103 for example, there are organs such as the heart 105, the lung region 106, the vertebra 107, and there may also be a tumor 108. It is often desirable to analyze or treat selected portions of such a cavity 103.
dashed line) is determined. Since there can be a multiplicity of transmitting antennas Tn and a multiplicity of receiving antennas Rn, a multiplicity of- such paths crisscrossing the entire chest cavity can be studied. From this information. using well known techniquest a dielectric image of the chest cavity can be generated. Such an image displays the various organs in the cavity# and when suitably made, can reveal the presence of tumor 108. The dielectric propertiesi and thus a dielectric image, can be determined as a function of position within the material being probed. Since dielectric image is very sensitive to the presence of water, it can also give an assessment of the lung water content; Cf. "microwave Methods of measuring Changes in Lung Watern, by M. F,. Iskander and C. H. Durney, Journal of Microwave Power, vol. 18(3), 1983, p. 265.
Note that although the antennas have been labeled as either transmitting or receiving antennas, any given antenna can serve either function.
01 02 03 04 05 06 07 08 09 10 11 12 13 14 is In the treatment mode, it is desirable to reduce or 16 eliminate the tumor 108 by hyperthermia, i.e., by 17 selectively heating only the tumor region 108 to a high 18 temperature. Thus, by selecting a suitable group of 19 antennas to transmit, one can selectively deposit electromagnetic energy in the region of the tumor 108; Cf. 21 "Two- dimensional Technique to Calculate the E14 Power 22 Deposition Pattern in the Human Body', by M. F. Iskander, 23 P. 7. Turner. J. B. DuBow and J. Kao. Journal of Microwav 24 Power, vol. 17(3), 1982o p. 175.
26 27 28 29 30 31 32 33 34 The broadband capability of the antennas is an advantage in the above applications for the following reasons: structures (e.g., heart, tumor) of different sizes require different frequencies for their best definition in the image; highly lossy regions such as fluids may require employment of relatively low frequencies so that the electromagnetic losses are acceptable; in time-donain application, simultaneous information at a multiplicity of frequencies can be developed.
The broadband capability of the antennas is an advantage in the above application because for a given situations one can select the frequency that simultaneously produces the optimum deposition of power and localization of the heating using known techniques.
An example of the inventive transmitting antenna 150 Is shown in Figure 2. A coaxial connecting means, such as coaxial connector 151 is electrically connected to a stripline adapter 153 which is capable of transmitting electromagnetic energy from the coaxial connector 151 to a stripline section with metallic central strip 155. An especially useful stripline adapter is a model No. 3070-1404-10 designed by Omni-Spectra, or other types of microwave stripline adapters. other types of transmission means may be utilized to transmit electromagnetic energy to the antenna For example, a strip transmission line may be electrically connected to the stripline section having the metallic central strip 155. As a commercial coaxial-to-stripline transition means has been utilized, the dimensions included herein reflect this means. one knowledgeable in the art would realize that the dimensions may be altered to change frequency coverage and to fine-tune performance.
01 02 03 04 06 07 08 09 11 12 13 14 16 17 is metallic center strip 155 has a front end 157, a flat strip 19 body 159, a flat strip face 161, and a distal end 163. The front end 157 is electrically connected to the center 21 conductor 169 of the stripline adapter 153. Solder is a 22 particularly useful connecting means. Flat strip body 159 23 may also be tapered to come to a point at front end 157 to 24 provide a smooth electrical transition between the center conductor 169 and the center strip 155. The strip face 161 26 is bent at approximately right angles to strip body 159, and 27 has a height that Is measured from the right angle bend to 28 distal end 163. The height is compatible with the desired 29 frequency coverage. The longer the height, the more lower frequency coverage is allowed. A 4" height permits a 31 frequency range of approximately 2 KHz 4 1 GHz. A 5mm 32 height extends the upper frequency limit to approximately 33 2 GHz. An upward frequency limit of 4 GHz is attainable as 34 well. The metallic center strip 155 can be made of any metal. Copper, brass, or aluminum are especially useful.
01 02 03 04 05 06 07 08 09 10 11 12 13 14 15 The void between the ground plane 165 and the center 16 strip 155 is largely filled with a dielectric 167. The 17 dielectric 167 should have a very high dielectric constant 18 and a very low loss. By loss, we mean the dissipation of 19 energy. The dielectric 167 can be a ceramic dielectric, and 20 comprised of material such as Barium Titanate or Lead 21 zirconate Titanate. A crystalline dielectric may also be 22 used, although more expensive. The thickness of the 23 dielectric 167 is determined by the stripline adapter 153 24 used. The dielectric 167 acts to make the capacitance of 25 the center strip 155 very large.
26 27 28 29 30 31 32 33 34 A ground plane 165 extends from stripline adapter 153 to the right angle bend in the center strip 155, so that the distal end 163 extends away from the ground plane 165 and so that a void exists between the center strip 155 and the ground plane 165. Ground plane 165 is comprised of a metal. Commercial grade stainless steel is particularly useful. It is desirable to keep the ground plane and center strip as short at possible, to permit the apparatus to remain as compact as possible and to allow the use of as many antennas as possible.
The construction of the antenna is completed by enclosing the center strip 155 by metallic walls 181, 182, 183, and 184, which contact the ground plane 165 and the adapter 153 electrically, as shown in Figure 2A. The walls add rigidity and prevent leakage of the electromagnetic radiation. The strip face 161 is approximately centered in the rectangular opening created by the edges of the walls and the edge of the ground plane 165. Thus, the distance between an edge of the strip face 161 and the adjacent edge of a wall is substantially the thickness of the dielectric 167. The entire void space in the antenna enclosed by the walls, including the set back 168 at the dielectric edge, is filled with a loss-less, non-conducting material such as a mixture of epoxy and alumina which sets hard, seals the antenna, and makes it more rugged.
01 02 03 04 05 06 07 08 09 10 11 12 13 14 is 16 17 is 19 20 21 22 23 A receiving electromagnetic antenna is comprised in 24 essentially the same manner as the transmitting antenna, and 25 is positioned in the tool in the same manner as the 26 transmitting antenna, so that the receiving antenna can 27 receive the electromagnetic energy which has traveled 28 through the material that is analyzed.
29 30 31 32 33 34 The ground plane 165 and the walls 181, 182, 183, and 184 are fixedly connected to an electromagnetic coupling or analyzing tool as seen in Figure 3. The strip face 161 is positioned to lie flush with the tool face 171 (which is the same as the tool face 111 of Figure 1), so that the transmitting antenna 150 can transmit electromagnetic energy into a material such as mammal tissue. A conductive substance, known in the art, is usually placed on the outside of the mammal tissue, to permit a sufficient flow of electromagnetic energy into the tissue. Void space 173 is filled with a loss-less, non-conducting material such as an epoxyaluminum compound. The ground plane 165 and the walls 181, 182, and 183 connect to the tool face.
The present invention is especially useful in the field of microwave diagnostic& of fluid content and fluid quantity. For example, the apparatus can couple electromagnetic energy into mammal tissue. The electromagnetic energy can be monitored to provide an indication of the amount and distribution of a fluid, such as water, inside the mammal tissue. One particularly useful application is to measure the water content in a lung. The present apparatus is very compact, and therefore requires a much smaller skin contact area. Also, many antennas can be placed on a chest cavity, to obtain a well defined image of the chest cavity. The inventive antennas can be mathematically described as a point source, thus making analysis of the data easier. A conductive substance should be placed on the outside of the chest cavity. to permit a sufficient flow of electromagnetic energy into the chest cavity.
01 02 03 04 05 06 07 08 09 10 11 12 13 14 is 16 17 is 19 20 In another embodiment, the present invention can be used in 21 the field of microwave hyperthermia. The apparatus can
22 couple electromagnetic energy into the interior portion of a 23 mammal, so that the electromagnetic energy is focused to 24 heat and thereby reduce the size of or destroy a tumor.
Tumor reduction therapy or cancer therapy by hyperthermia, 26 combined with radiation or drugs is known in the art to 27 28 29 30 31 32 33 34 The prior art (Iskander et al.) has the drawback that the electric field vanishes at some distance from the tool face, since the fields in the two parallel slots are oppositely directed. No such cancellation occurs with the present invention. Furthermore, the incorporation of a resistor in Iskander et alts antenna introduces a power limitation.
either stop or slow down the growth of cancer cells# or cause the death of the cancer cells.
The present invention has the advantage over the prior act that many frequencies can be selected. Because there is no limitation to the power handling capability in the inventive antenna, the present invention is particularly suited for depositing microwave power into a localized area inside a 01 02 mammal, such as a human. Either a single antenna or an array of antennas could be used.
03 04 05 06 07 08 09 10 11 12 13 14 is 16 The apparatus can operate in the frequency domain, using a 17 single frequency, multiple frequencies (such as a simultaneous, selectable, or time-multiplexed for example), 19 or swept frequency techniques. Or, the apparatus can operate in the time domain, using pulses of a wide variety 21 of shapes, widths, rise and fall times, etc. when the 22 pulses are transformed to the frequency domain, either 23 electronically using a spectrum analyzer, or numerically 24 using mathematical transforms, the same information is 2S obtained as would be given by a frequency domain tool.
26 27 28 29 30 31 32 33 34 In yet another embodiment, the apparatus can be implanted inside the body of a mammal, and used as a radio frequency antenna. Either a single antenna or an array of antennas could be used. As the Inventive antenna can be made very small (as small as approximately 10 m= long and approximately 5 mm high), it is particularly suitable to this application. As the antenna gets smaller, the frequency coverage shifts to higher frequencies. The apparatus can be constructed with a commercial micro- coaxial connector. However, smaller devices can be constructed through the use of a customized coaxial connector.
A prototype tool was constructed, with the Inventivei antennas. The tool consists of one transmitting and one receiving antenna, the distance between them being variable.
An acceptable dielectric antenna must meet the following criteria:
-is- It must be able to couple sufficient energy into and from the material at its operating frequency to allow probing of the material; 01 02 03 04 05 06 07 08 09 10 11 12 13 14 The first of the above criteria is tested by measuring the 15 return loss for the transmitting antenna, and the 16 transmission loss from the transmitting to the receiving 17 antenna - both as a function of frequency. These 18 measurements are shown in Figure 4 where the tool is placed 19 in air and against brine of conductivity 0.5 mho/m (to represent a biological medium). The return loss curve in 21 brine shows that sufficient energy is entering the brine 22 over the frequency range of the measuring device 23 (Hewlett-Packard HP8505A Network Analyzer; 500 KHz - 24 25 26 27 28 29 30 31 32 33 34 (ii) This probing energy must penetrate into the material, rather than clinging to the surface of the tool (i.e., it must travel as a freely propagating wave rather than a surface wave guided along the tool face).
In the present instance, the above two conditions must hold over the entire range of the frequency of operation.
1300 MHZ) to permit probing. The transmission loss shows that sufficient energy is being received at the receiving antenna to permit measurements.
measurements were made by using another measuring device (HP3577A Network Analyzer; SHZ - 200 MHz) to test the low frequency limitation of the antenna. The results are shown in Figure 5t showing that the low frequency limitation is about 5 KHZ. The improved return loss performance in the 200 MHz region (at Figure 4) results from a drying (curing) of the epoxy alumina filling between measurements.
01 02 03 04 05 06 07 08 09 10 11 12 13 14 is 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 Figure 6 shows time-domain transmission measurements at various distances (d). to a metal reflector plate in the brine. The change in amplitude of the received pulse as a function of the distance of the metallic reflector shows that the energy has penetrated into the brine out to the location of the plate.
while a preferred embodiment of the invention has been described and Illustrated, it should be apparent that many modifications can be made thereto without departing from the spirit or scope of the invention. Accordingly, the invention is not limited by the foregoing description, but is only limited by the scope of the claims appended hereto.
01 02 03 04 05 06 07 08 09 10 11 12 13 14 is 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34

Claims (1)

  1. CLAIMS.
    1. Apparatus for coupling electromagnetic energy into materials comprising a measuring tool having a tool face, said measuring tool further comprising an electromagnetic transmitting antenna, said transmitting antenna further comprising:
    (a) a coaxial cable connecting means and means to transmit electromagnetic energy therethrough; (b) a stripline adapter capable of transmitting electromagnetic energy from said coaxial cable connecting means to a stripline having a metallic central strip, said center strip having a front end, a flat strip body, a flat strip face, and a distal end, said front end electrically connected to a center conductor of said stripline adapter, said strip face bent at approximately right angles to said strip body and having a height measured from said right angle bend to said distal end that is compatible with a desired frequency coverage; (c) a ground plane which extends from said stripline adapter to said right angle bend, so that said distal end extends away from said ground plane and so that a void exists between said center strip and said ground plane; (d) a dielectric largely filling said void, said dielectric comprised of a material having a very high dielectric constant and a very low energy loss, so that said transmitting antenna is positioned so that said ground plane Is fixedly 01 02 03 04 05 06 07 08 09 10 11 12 13 14 is 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 connected to said measuring tool and said strip face is positioned to lie flush with said tool face so that said transmitting antenna can transmit electromagnetic energy into said material; (e) an enclosure surrounding said stripline comprising four metallic walls, said walls positioned in electrical contact with said ground plane and said stripline adapter, so that said strip face is nearly centered in the opening created by said walls and said ground plane; (f) a loss-less, non-conducting material which fills in any remaining open space in said enclosure so that said non-conducting material forms an additional wall that is nearly flat with said strip face; (g) said receiving electromagnetic antenna comprised in essentially the same manner as said transmitting antenna, said receiving antenna positioned in said measuring tool in the same manner as said transmitting antenna, so that said receiving antenna can receive said electromagnetic energy which has traveled through said material; and (h) means for monitoring the amplitude and the phase of said received electromagnetic energy.
    2. Apparatus as recited in Claim 1 further comprising a means for positioning said tool face near said material.
    01 02 03 04 05 06 07 08 09 10 11 12 13 14 is 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 3. Apparatus as recited in Claim 1 wherein said electromagnetic energy is focused to heat and thereby reduce the size of a tumor in a mammal.
    4. Apparatus as recited in Claim 1 wherein said electromagnetic energy is focused to heat and thereby destroy a tumor in a mammal.
    5. Apparatus as recited in Claim 1 wherein said antennas are positioned on a belt-mounted device.
    6. Apparatus as recited in Claim 1, further comprising a plurality of receiving antennas.
    7. Apparatus as recited in Claim 6 further comprising a plurality of transmitting antennas.
    8. Apparatus as recited in Claim 7 wherein said materials are mammal tissue and water.
    Apparatus as recited in Claim 1, wherein broadband measurements are taken to determine said dielectric properties as a function of position within said material.
    10. An apparatus for coupling electromagnetic energy to determine the quantity of a fluid in a material, said apparatus having a tool face and further comprising a first electromagnetic -transmitting antenna, said first transmitting antenna further comprising:
    (a) a coaxial cable connecting means and means to transmit electromagnetic energy therethrough; 01 02 03 04 05 06 07 08 09 10 11 12 13 14 is 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 (b) a stripline adapter capable of transmitting electromagnetic energy from said coaxial cable connecting means to a stripline having a metallic central strip, said center strip having a front end, a flat strip body, a flat strip face, and a distal end, said front end electrically connected to a center conductor of said stripline adapter, said strip face bent at approximately right angles to said strip body and having a height measured from said right angle bend to said distal end that is compatible with a desired frequency coverage; (c) a ground plane which extends from said stripline adapter to said right angle bend, so that said distal end extends away from said ground plane and so that a void exists between said center strip and said ground plane; (d) a dielectric filling most of said void, said dielectric composed of a material having a very high dielectric constant and a very low energy loss, so that said first transmitting antenna is positioned so that said ground plane is fixedly connected to said logging tool and said strip face is positioned to lie flush with said tool face so that said first transmitting antenna can transmit electromagnetic energy into said material; (e) an enclosure surrounding said stripline comprising four metallic walls, said walls positioned in electrical contact with said ground plane and said stripline adapter, so that said strip face is nearly centered in the opening created by said walls and said ground plane; 01 02 03 04 06 07 08 09 11 12 13 14 is 16 17 18 19 21 22 23 24 26 27 12. Apparatus is recited in Claim 1 or 10 wherein said 28 transmitting antenna can alternately function as a 29 receiving antenna and said receiving antenna can alternately function as a transmitting antenna.
    31 32 33 34 f a loss-less, non-conducting material which fills in any remaining open space in said enclosure so that said non-conducting material forms an additional wall that is nearly flat with said strip face; (g) said receiving electromagnetic antenna comprised in essentially the same manner as said transmitting antenna, said receiving antenna positioned in said apparatus in the same manner as said transmitting antenna, so that said receiving antenna can receive said electromagnetic energy which has traveled through said material,- and (h) means for monitoring the amplitude and the phase of said electromagnetic energy, so that the quantity of said fluid can be determined.
    11. Apparatus as recited in Claim 1 or 10 wherein said transmitting antenna transmits and said receiving antenna receives electromagnetic energy over a frequency range of 2 KHz to 4 GHz.
    13. Apparatus as recited in Claim 12 further comprising a belt-mount, said beltmount substantially conforming to 01 02 03 04 14. Apparatus as recited in Claim 13 further comprising a plurality of receiving antennas.
    06 07 08 09 10 11 12 13 14 is 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 the outside of a mammal tissue and holding said transmitting and receiving antennas.
    15. Apparatus as recited in Claim 14 further comprising a plurality of transmitting antennas.
    16. Apparatus as recited in Claim 10 wherein said fluids are water.
    17. Apparatus as recited in Claim 1 or 10 wherein said ground plane is no greater than 10 m= in length.
    18. Apparatus as recited in Claim 1 or 10 wherein said strip face has a height that is no greater than 5 mm.
    19. Apparatus as recited in Claim 1 or 10 wherein said electromagnetic energy is monitored to provide an indication of the amount and distribution of a fluid inside mammal tissue.
    20. Apparatus as recited in Claim 1 or 10 wherein no receiving antenna is Incorporated.
    21. Apparatus as recited in Claim 1 or 10 wherein said apparatus Is implanted inside a mammal, as a radio frequency antenna.
    22. Apparatus as recited in Claim 21 wherein said apparatus does not incorporate a receiving antenna.
    01 02 03 04 05 06 07 08 09 10 25.
    11 12 13 14 is 16 17 18 19 20 21 22 2J 24 25 26 27 28 29 30 31 32 (c) 33 34 23. Apparatus as recited in Claim 1 or 10 wherein a strip transmission line is electrically connected to said stripline, so that electromagnetic energy can be transmitted thereto.
    24. Apparatus as recited in Claim 10 wherein said nature of said fluid is determined as a function of position in said material.
    Method for coupling electromagnetic energy into materials comprising the steps of:
    forming a measuring tool having a tool face, an electromagnetic transmitting antenna and a receiving antenna, said transmitting antenna further comprising:
    (a) a coaxial cable connecting means and meant to transmit electromagnetic energy therethrough; (b) a stripline adapter capable of transmitting electromagnetic energy from said coaxial cable connecting fneans to a stripline having a metallic central strip, said center strip having a front end, a flat strip body, a flat strip face, and a distal end, said front end electrically connected to a center conductor of said stripline adapter, said strip face bent at approximately right angles to said strip body and having a height measured from said right angle bend to said distal end that is compatible with a desired frequency coverage; a ground plane which extends from said stripline adapter to said right angle bend, so that said distal end extends away from said ground plane and 01 02 03 04 05 06 07 08 09 10 11 12 13 14 is 16 17 is 19 20 21 22 23 24 25 26 27 28 (g) 29 30 31 32 33 34 so that a void exists between said center strip and said ground plane; (d) a dielectric largely filling said void, said dielectric comprised of a material having a very high dielectric constant and a very low energy loss, so that said transmitting antenna Is positioned so that said ground plane is fixedly connected to said measuring tool and said strip face is positioned to lie flush with said tool face so that said transmitting antenna can transmit electromagnetic energy into said material; (e) an enclosure surrounding said stripline comprising four metallic walls, said walls positioned in electrical contact with said ground plant and said stripline adapter, so that said strip face is nearly centered in the opening created by said walls and said ground plane; a loss-less, non-conducting material which fills in any remaining open space in said enclosure so that said non-conducting material- forms an additional wall that is nearly flat with said strip face; said receiving antenna comprised in essentially the same manner as said transmitting antenna, and positioned in said measuring tool in the same manner as said transmitting antenna, so that said receiving antenna receives said electromagnetic energy which has traveled through said material; interconnecting said measuring tool with a means for monitoring said electromagnetic energy whereby said dielectric properties can be measured; and 01 02 03 04 05 06 07 08 09 10 11 12 13 14 15 16 17 is 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 33. method as recited in Claim 25 wherein said broadband 34 measurements are taken to determine said dielectric interconnecting said measuring tool with a source of electromagnetic energy.
    26. method as recited in Claim 25 further comprising a means for positioning said tool face near said material.
    27. Method as recited in Claim 25 wherein said electromagnetic energy is focused to heat and thereby reduce the size of a tumor in a mammal.
    28. method as recited in Claim 25 wherein said electromagnetic energy is focused to heat and thereby destroy a tumor in a mammal.
    29. method as recited in Claim 25 wherein said antennas are positioned on a belt-mount device.
    30. Method as recited in Claim 25 further comprising a plurality of receiving antennas.
    31. Method as recited in Claim 30 further comprising a plurality of transmitting antennas.
    32. Method as recited in Claim 31 wherein said materials having dissimilar dielectric properties are mammal tissue and water.
    01 02 03 04 05 06 07 08 09 10 11 12 13 14 is 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 (d) 34 properties as a function of position within said material.
    34. Method for coupling electromagnetic energy to determine the quality of a fluid in a material, comprising the steps of:
    forming an apparatus having a tool face, an electromagnetic transmitting antenna, and a receiving antenna, said transmitting antenna further comprising:
    (a) a coaxial cable connecting means and means to transmit electromagnetic energy therethrough; (b) a stripline adapter capable of transmitting electromagnetic energy from said coaxial cable connecting means to a stripline having a metallic central strip, said center strip having a front end, a flat strip body, a flat strip face, and a distal end, said front end electrically connected to a center conductor of said stripline adapter, said strip face bent at approximately right angles to said strip body and having a height measured from said right angle bend to said distal end that is compatible with a desired frequency coverage; (c) a ground plane which extends from said stripline adapter to said right angle bend, so that said distal end extends away from said ground plane and so that a void exists between said center strip and said ground plane; a dielectric largely filling said void, said dielectric comprised of a material having a very 01 02 03 04 05 06 07 08 09 10 11 12 13 14 is 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 high dielectric constant and a very low energy loss, so that said transmitting antenna is positioned so that said ground plane is fixedly connected to said measuring tool and said strip face is positioned to lie flush with said tool face so that said transmitting antenna can transmit electromagnetic energy into said material; (e) an enclosure surrounding said stripline comprising four metallic walls, said walls positioned in electrical contact with said ground plane and said stripline adapter, so that said strip face is nearly centered in the opening created by said walls and said ground plane; (f) a loss-less, non-conducting material which fills in any remaining open space in said enclosure so that said non-conducting material forms an additional wall that is nearly flat with said strip face; (g) said receiving antenna comprised in essentially the same manner as said transmitting antenna, and positioned in said apparatus in the same manner as said transmitting antenna, so that said receiving antenna receives said electromagnetic energy which has traveled through said material; interconnecting said measuring tool with a means for monitoring said electromagnetic energy whereby said nature of said fluid can be determined; and interconnecting said apparatus with a source of electromagnetic energy.
    01 02 03 04 05 06 07 08 09 10 11 12 13 14 is 16 17 18 19 20 21 22 2-3 24 25 40. Method as recited In Claim 39 wherein some of said 26 antennas are positioned on said tool face and some 27 antennas are positioned on said belt-mount.
    28 29 30 31 32 33 34 35. Method as recited in Claim 31 or 40 wherein said transmitting antenna transmit& and said receiving antenna receives electromagnetic energy over a frequency range of 2 KHz to 4 GHz.
    36. Method as recited in Claim 25 or 34 wherein said transmitting antenna can alternately function as a receiving antenna and said receiving antenna can alternately function as a transmitting antenna.
    37. Method as recited in Claim 36 further comprising a belt-mount, said belt-mount substantially conforming to the outside of a mammal tissue and holding said transmitting and receiving antennas.
    38. Method as recited in Claim 37 further comprising a plurality of receiving antennas.
    39. method as recited in Claim 38 further comprising a plurality of transmitting antennas.
    41. Method as recited in Claim 34 wherein said fluids are water.
    42. method as recited in Claim 25 or 34 wherein said ground plane is no, greater than 10 mm in length.
    Method as recited in Claim 25 or 34 wherein said strip face has a height that is no greater than 5 mm.
    01 02 03 04 05 06 07 08 09 10 11 12 13 14 is 16 17 18 19 20 21 22 23 24 49. method as recited In Claim 40 wherein 'said quantity of said fluid is determined as a function of position 26 within said material.
    27 28 29 30 31 32 33 34 method as recited in Claim 25 or 34 wherein said electromagnetic energy is monitored to provide an indication of the amount and distribution of a fluid inside mammal tissue.
    45. method as recited in Claim 25 or 34 wherein no receiving antenna is incorporated.
    46. Method as recited in Claim 25 or 34 wherein said apparatus Is implanted inside a mammal, as a radio frequency antenna.
    47. Method as recited in Claim 46 wherein said apparatus does not incorporate a receiving antenna.
    48. method as recited in Claim 25 or 34 wherein a strip transmission line is electrically connected to said stripline, so that electromagnetic energy. can be transmitted thereto.
GB9126811A 1990-12-20 1991-12-18 Measuring and treatment tool incorporating broad band stripline aerials and useful in medical technology Withdrawn GB2251080A (en)

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Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0804900A1 (en) * 1996-05-02 1997-11-05 Jack E. Bridges Microwave method to detect and locate cancers in heterogenous tissues
EP0694282A3 (en) * 1994-07-01 1997-11-05 Jack E. Bridges Breast cancer detection and imaging by electromagnetic millimeter waves
US5807257A (en) * 1994-07-01 1998-09-15 Interstitial, Inc. Breast cancer detection, imaging and screening by electromagnetic millimeter waves
US6751500B2 (en) 1999-07-28 2004-06-15 Medrad, Inc. Apparatuses and methods for extravasation detection
US7047058B1 (en) 2001-02-06 2006-05-16 Medrad, Inc. Apparatuses, systems and methods for extravasation detection
US7122012B2 (en) 2001-07-26 2006-10-17 Medrad, Inc. Detection of fluids in tissue
US7591792B2 (en) 2001-07-26 2009-09-22 Medrad, Inc. Electromagnetic sensors for biological tissue applications and methods for their use
US10722136B2 (en) 2011-09-02 2020-07-28 Battelle Memorial Institute Wireless and power-source-free extravasation and infiltration detection sensor

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19520021A1 (en) * 1995-05-31 1996-12-05 Umwelt Geraete Technik Gmbh Determining dielectric constants in mixture e.g. in arable soil or in liquid
CN112933414B (en) * 2021-01-27 2022-06-10 内蒙古科技大学 External thermotherapy equipment and external microwave thermotherapy antenna thereof

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4678997A (en) * 1984-08-20 1987-07-07 Dresser Industries, Inc. Method and apparatus for dielectric well logging of subsurface earth formations with a lumped constant antenna

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4271848A (en) * 1979-01-11 1981-06-09 Bio Systems Design, Corp. Apparatus for electromagnetic radiation of living tissue and the like
US4488559A (en) * 1981-06-30 1984-12-18 University Of Utah Apparatus and method for measuring lung water content
US4974587A (en) * 1988-12-22 1990-12-04 Bsd Medical Corporation Applicator array and positioning system for hyperthermia

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4678997A (en) * 1984-08-20 1987-07-07 Dresser Industries, Inc. Method and apparatus for dielectric well logging of subsurface earth formations with a lumped constant antenna

Cited By (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0694282A3 (en) * 1994-07-01 1997-11-05 Jack E. Bridges Breast cancer detection and imaging by electromagnetic millimeter waves
US5807257A (en) * 1994-07-01 1998-09-15 Interstitial, Inc. Breast cancer detection, imaging and screening by electromagnetic millimeter waves
EP0804900A1 (en) * 1996-05-02 1997-11-05 Jack E. Bridges Microwave method to detect and locate cancers in heterogenous tissues
US6751500B2 (en) 1999-07-28 2004-06-15 Medrad, Inc. Apparatuses and methods for extravasation detection
US7047058B1 (en) 2001-02-06 2006-05-16 Medrad, Inc. Apparatuses, systems and methods for extravasation detection
US9289550B1 (en) 2001-02-06 2016-03-22 Bayer Healthcare Llc Apparatus and method for detecting fluid extravasation
US7591792B2 (en) 2001-07-26 2009-09-22 Medrad, Inc. Electromagnetic sensors for biological tissue applications and methods for their use
US7122012B2 (en) 2001-07-26 2006-10-17 Medrad, Inc. Detection of fluids in tissue
US10722136B2 (en) 2011-09-02 2020-07-28 Battelle Memorial Institute Wireless and power-source-free extravasation and infiltration detection sensor
US10987017B2 (en) 2011-09-02 2021-04-27 Battelle Memorial Institute Distributed extravasation detecton system
US11234608B2 (en) 2011-09-02 2022-02-01 Battelle Memorial Institute Extravasation and infiltration detection device with fluid guide provided on a substrate of the detection device to adjust fluid rate based on detection signal
US11883144B2 (en) 2011-09-02 2024-01-30 Battelle Memorial Institute Integrated extravasation and infiltration detection device on a RF isolated flexible substrate with fluid guide to detect fluid changes via signal comparison
US11883143B2 (en) 2011-09-02 2024-01-30 Battelle Memorial Institute Wireless and power-source-free extravasation and infiltration detection sensor circuitry provided on a substrate with signal splitter
US11986281B2 (en) 2011-09-02 2024-05-21 Battelle Memorial Institute Distributed extravasation detection system for fluid change and to control the fluids levels in a body via wireless interface based on rate of activation

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CA2057947A1 (en) 1992-06-21
DE4142348A1 (en) 1992-06-25
GB9126811D0 (en) 1992-02-19

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