GB2228263B - Test animal in which a cholinergenic neuron has been destroyed; and conjugate for the preparation thereof - Google Patents

Test animal in which a cholinergenic neuron has been destroyed; and conjugate for the preparation thereof

Info

Publication number
GB2228263B
GB2228263B GB9003592A GB9003592A GB2228263B GB 2228263 B GB2228263 B GB 2228263B GB 9003592 A GB9003592 A GB 9003592A GB 9003592 A GB9003592 A GB 9003592A GB 2228263 B GB2228263 B GB 2228263B
Authority
GB
United Kingdom
Prior art keywords
cholinergenic
neuron
conjugate
destroyed
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
GB9003592A
Other languages
English (en)
Other versions
GB2228263A (en
GB9003592D0 (en
Inventor
Masaya Tohyama
Sadao Shiosaka
Yukitsuka Kudo
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Tanabe Seiyaku Co Ltd
Original Assignee
Tanabe Seiyaku Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tanabe Seiyaku Co Ltd filed Critical Tanabe Seiyaku Co Ltd
Publication of GB9003592D0 publication Critical patent/GB9003592D0/en
Publication of GB2228263A publication Critical patent/GB2228263A/en
Application granted granted Critical
Publication of GB2228263B publication Critical patent/GB2228263B/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
    • A01K67/027—New or modified breeds of vertebrates
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K19/00—Hybrid peptides, i.e. peptides covalently bound to nucleic acids, or non-covalently bound protein-protein complexes
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2227/00—Animals characterised by species
    • A01K2227/10—Mammal
    • A01K2227/105—Murine
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2267/00—Animals characterised by purpose
    • A01K2267/03—Animal model, e.g. for test or diseases
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2267/00—Animals characterised by purpose
    • A01K2267/03—Animal model, e.g. for test or diseases
    • A01K2267/0306—Animal model for genetic diseases
    • A01K2267/0312—Animal model for Alzheimer's disease

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Environmental Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Biodiversity & Conservation Biology (AREA)
  • Animal Husbandry (AREA)
  • Zoology (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
GB9003592A 1989-02-17 1990-02-16 Test animal in which a cholinergenic neuron has been destroyed; and conjugate for the preparation thereof Expired - Fee Related GB2228263B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP3900389 1989-02-17

Publications (3)

Publication Number Publication Date
GB9003592D0 GB9003592D0 (en) 1990-04-11
GB2228263A GB2228263A (en) 1990-08-22
GB2228263B true GB2228263B (en) 1992-07-29

Family

ID=12540945

Family Applications (1)

Application Number Title Priority Date Filing Date
GB9003592A Expired - Fee Related GB2228263B (en) 1989-02-17 1990-02-16 Test animal in which a cholinergenic neuron has been destroyed; and conjugate for the preparation thereof

Country Status (4)

Country Link
DE (1) DE4004573A1 (it)
FR (1) FR2649308A1 (it)
GB (1) GB2228263B (it)
IT (1) IT9019400A1 (it)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4337007C1 (de) * 1993-10-29 1994-12-15 Andreas Dr Med Nickel Modifiziertes Tiermodell zur Testung von AIDS-Impfstoffen
AR021467A1 (es) * 1998-08-27 2002-07-24 Duphar Int Res Un mamifero no humano con el cerebro artificialmente danado, metodo para ensayar compuestos o composiciones farmaceuticas en el mamifero y uso de loscompuestos o composiciones.
EP1161525A2 (en) * 1999-03-12 2001-12-12 Brown University Research Foundation Methods and compositions for regulating memory consolidation
US6921538B2 (en) * 2002-05-10 2005-07-26 Allergan, Inc. Therapeutic treatments for neuropsychiatric disorders

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3369466D1 (en) * 1982-05-12 1987-03-05 Harvard College Fused genes encoding hybrid proteins, cloning vectors containing them and the use thereof
US4962188A (en) * 1985-12-06 1990-10-09 Cetus Corporation Recombinant ricin toxin A chain conjugates
IN165717B (it) * 1986-08-07 1989-12-23 Battelle Memorial Institute
WO1989009225A1 (en) * 1988-03-28 1989-10-05 The Regents Of The University Of California Nerve growth factor peptides

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
Neurochem. Int. 1988, 12(4), 475-482 *
Neurosci. Lett. 1989, 102(2-3), 125-130 *
Neuroscience 1989, 29(2), 329-338 *
Neuroscience 1989, 32(3), 685-700 *

Also Published As

Publication number Publication date
FR2649308A1 (fr) 1991-01-11
DE4004573A1 (de) 1990-08-23
GB2228263A (en) 1990-08-22
GB9003592D0 (en) 1990-04-11
IT9019400A0 (it) 1990-02-16
IT9019400A1 (it) 1990-08-18

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Legal Events

Date Code Title Description
PCNP Patent ceased through non-payment of renewal fee

Effective date: 19940216