GB2224573B - A method for the assessment of sample dna fragmentation and polynucleotide probes therefor - Google Patents

A method for the assessment of sample dna fragmentation and polynucleotide probes therefor

Info

Publication number
GB2224573B
GB2224573B GB8923621A GB8923621A GB2224573B GB 2224573 B GB2224573 B GB 2224573B GB 8923621 A GB8923621 A GB 8923621A GB 8923621 A GB8923621 A GB 8923621A GB 2224573 B GB2224573 B GB 2224573B
Authority
GB
United Kingdom
Prior art keywords
assessment
dna fragmentation
sample dna
polynucleotide probes
probes therefor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
GB8923621A
Other versions
GB2224573A (en
GB8923621D0 (en
Inventor
Alec John Jeffreys
Andrew Hawley Cawood
Michael Brian Timbrell Webb
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Imperial Chemical Industries Ltd
Original Assignee
Imperial Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Imperial Chemical Industries Ltd filed Critical Imperial Chemical Industries Ltd
Publication of GB8923621D0 publication Critical patent/GB8923621D0/en
Publication of GB2224573A publication Critical patent/GB2224573A/en
Application granted granted Critical
Publication of GB2224573B publication Critical patent/GB2224573B/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism
    • C12Q1/683—Hybridisation assays for detection of mutation or polymorphism involving restriction enzymes, e.g. restriction fragment length polymorphism [RFLP]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/166—Oligonucleotides used as internal standards, controls or normalisation probes
GB8923621A 1988-10-20 1989-10-19 A method for the assessment of sample dna fragmentation and polynucleotide probes therefor Expired - Fee Related GB2224573B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB888824531A GB8824531D0 (en) 1988-10-20 1988-10-20 Polynucleotide probes

Publications (3)

Publication Number Publication Date
GB8923621D0 GB8923621D0 (en) 1989-12-06
GB2224573A GB2224573A (en) 1990-05-09
GB2224573B true GB2224573B (en) 1993-05-12

Family

ID=10645480

Family Applications (2)

Application Number Title Priority Date Filing Date
GB888824531A Pending GB8824531D0 (en) 1988-10-20 1988-10-20 Polynucleotide probes
GB8923621A Expired - Fee Related GB2224573B (en) 1988-10-20 1989-10-19 A method for the assessment of sample dna fragmentation and polynucleotide probes therefor

Family Applications Before (1)

Application Number Title Priority Date Filing Date
GB888824531A Pending GB8824531D0 (en) 1988-10-20 1988-10-20 Polynucleotide probes

Country Status (5)

Country Link
JP (1) JPH0327300A (en)
DE (1) DE3935022A1 (en)
FR (1) FR2638171A1 (en)
GB (2) GB8824531D0 (en)
IT (1) IT1237107B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6207373B1 (en) 1998-02-25 2001-03-27 Nanogen, Inc. Methods for determining nature of repeat units in DNA

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2166445A (en) * 1984-11-12 1986-05-08 Lister Preventive Med Polynucleotide probes
EP0238329A2 (en) * 1986-03-19 1987-09-23 Zeneca Limited Improvements in genetic probes

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2166445A (en) * 1984-11-12 1986-05-08 Lister Preventive Med Polynucleotide probes
EP0238329A2 (en) * 1986-03-19 1987-09-23 Zeneca Limited Improvements in genetic probes

Also Published As

Publication number Publication date
IT8922092A0 (en) 1989-10-20
FR2638171A1 (en) 1990-04-27
GB8824531D0 (en) 1988-11-23
GB2224573A (en) 1990-05-09
IT1237107B (en) 1993-05-18
IT8922092A1 (en) 1991-04-20
DE3935022A1 (en) 1990-04-26
GB8923621D0 (en) 1989-12-06
JPH0327300A (en) 1991-02-05

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Legal Events

Date Code Title Description
732E Amendments to the register in respect of changes of name or changes affecting rights (sect. 32/1977)
PCNP Patent ceased through non-payment of renewal fee

Effective date: 19931019