GB2184321B - Confocal scanning microscope - Google Patents

Confocal scanning microscope

Info

Publication number
GB2184321B
GB2184321B GB8629923A GB8629923A GB2184321B GB 2184321 B GB2184321 B GB 2184321B GB 8629923 A GB8629923 A GB 8629923A GB 8629923 A GB8629923 A GB 8629923A GB 2184321 B GB2184321 B GB 2184321B
Authority
GB
United Kingdom
Prior art keywords
scanning microscope
confocal scanning
confocal
microscope
scanning
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB8629923A
Other versions
GB2184321A (en
GB8629923D0 (en
Inventor
John Graham White
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Medical Research Council
Original Assignee
Medical Research Council
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medical Research Council filed Critical Medical Research Council
Publication of GB8629923D0 publication Critical patent/GB8629923D0/en
Publication of GB2184321A publication Critical patent/GB2184321A/en
Application granted granted Critical
Publication of GB2184321B publication Critical patent/GB2184321B/en
Expired legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/0004—Microscopes specially adapted for specific applications
    • G02B21/002—Scanning microscopes
    • G02B21/0024—Confocal scanning microscopes (CSOMs) or confocal "macroscopes"; Accessories which are not restricted to use with CSOMs, e.g. sample holders
    • G02B21/0052—Optical details of the image generation
    • G02B21/0076—Optical details of the image generation arrangements using fluorescence or luminescence
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/0004—Microscopes specially adapted for specific applications
    • G02B21/002—Scanning microscopes
    • G02B21/0024—Confocal scanning microscopes (CSOMs) or confocal "macroscopes"; Accessories which are not restricted to use with CSOMs, e.g. sample holders
    • G02B21/0036—Scanning details, e.g. scanning stages
    • G02B21/0048—Scanning details, e.g. scanning stages scanning mirrors, e.g. rotating or galvanomirrors, MEMS mirrors
    • H—ELECTRICITY
    • H04—ELECTRIC COMMUNICATION TECHNIQUE
    • H04N—PICTORIAL COMMUNICATION, e.g. TELEVISION
    • H04N1/00—Scanning, transmission or reproduction of documents or the like, e.g. facsimile transmission; Details thereof
    • H04N1/04—Scanning arrangements, i.e. arrangements for the displacement of active reading or reproducing elements relative to the original or reproducing medium, or vice versa
    • H04N1/113—Scanning arrangements, i.e. arrangements for the displacement of active reading or reproducing elements relative to the original or reproducing medium, or vice versa using oscillating or rotating mirrors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N2021/6417—Spectrofluorimetric devices
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters
    • G01N2021/6463—Optics

Landscapes

  • Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Engineering & Computer Science (AREA)
  • Multimedia (AREA)
  • Signal Processing (AREA)
  • Microscoopes, Condenser (AREA)
GB8629923A 1985-12-17 1986-12-15 Confocal scanning microscope Expired GB2184321B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB858531011A GB8531011D0 (en) 1985-12-17 1985-12-17 Confocal scanning microscope

Publications (3)

Publication Number Publication Date
GB8629923D0 GB8629923D0 (en) 1987-01-28
GB2184321A GB2184321A (en) 1987-06-17
GB2184321B true GB2184321B (en) 1989-11-15

Family

ID=10589866

Family Applications (2)

Application Number Title Priority Date Filing Date
GB858531011A Pending GB8531011D0 (en) 1985-12-17 1985-12-17 Confocal scanning microscope
GB8629923A Expired GB2184321B (en) 1985-12-17 1986-12-15 Confocal scanning microscope

Family Applications Before (1)

Application Number Title Priority Date Filing Date
GB858531011A Pending GB8531011D0 (en) 1985-12-17 1985-12-17 Confocal scanning microscope

Country Status (1)

Country Link
GB (2) GB8531011D0 (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6148114A (en) 1996-11-27 2000-11-14 Ultrapointe Corporation Ring dilation and erosion techniques for digital image processing
US6288782B1 (en) 1993-06-17 2001-09-11 Ultrapointe Corporation Method for characterizing defects on semiconductor wafers

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE455736B (en) * 1984-03-15 1988-08-01 Sarastro Ab PROCEDURE KIT AND MICROPHOTOMETRATION AND ADDITIONAL IMAGE COMPOSITION
US4997242A (en) * 1988-03-07 1991-03-05 Medical Research Council Achromatic scanning system
DE3853637T2 (en) * 1988-07-06 1995-12-21 Medical Res Council ACHROMATIC SCAN SYSTEM.
GB8817672D0 (en) * 1988-07-25 1988-09-01 Sira Ltd Optical apparatus
GB9015793D0 (en) * 1990-07-18 1990-09-05 Medical Res Council Confocal scanning optical microscope
US5127730A (en) * 1990-08-10 1992-07-07 Regents Of The University Of Minnesota Multi-color laser scanning confocal imaging system
FR2673718B1 (en) * 1991-03-04 1993-05-14 Dilor RAMAN SPECTROMETRY APPARATUS.
US5334830A (en) * 1991-05-29 1994-08-02 Olympus Optical Co., Ltd. Scanning optical microscope having a compact confocal optical system for adjusting position of aperture
US5822061A (en) * 1992-01-20 1998-10-13 Dilor Spectrometry apparatus
US5296703A (en) * 1992-04-01 1994-03-22 The Regents Of The University Of California Scanning confocal microscope using fluorescence detection
US5479252A (en) * 1993-06-17 1995-12-26 Ultrapointe Corporation Laser imaging system for inspection and analysis of sub-micron particles
US5619371A (en) * 1995-03-02 1997-04-08 Southern Research Institute Confocal optical microscopy system for multi-layer data storage and retrieval
SE9501243L (en) * 1995-04-05 1996-10-06 Contest Marketing Ab Apparatus for automatic magnetic powder testing
GB2312115B (en) * 1996-04-09 2000-03-22 Icg Ltd An imaging arrangement for an image writing apparatus
US6108127A (en) * 1997-05-15 2000-08-22 3M Innovative Properties Company High resolution confocal microscope
US6548796B1 (en) 1999-06-23 2003-04-15 Regents Of The University Of Minnesota Confocal macroscope
JP4642397B2 (en) * 2004-07-12 2011-03-02 オリンパス株式会社 Optical scanning microscope
US7317519B2 (en) * 2004-10-29 2008-01-08 Agilent Technologies, Inc. Swept-angle SPR measurement system
CH708797B1 (en) 2007-08-17 2015-05-15 Tecan Trading Ag Sample part magazine for a slide transport device of a laser scanner device.
AT14178U1 (en) 2007-10-22 2015-05-15 Tecan Trading Ag Slide transporter for a laser scanner device
DE102008010435B4 (en) 2008-02-21 2010-07-29 Tecan Trading Ag Data acquisition procedure with a laser scanner device

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1185839A (en) * 1966-08-10 1970-03-25 Leitz Ernst Gmbh Improvements in or relating to Devices for Optically Scanning Microscopic Objects
WO1979001027A1 (en) * 1978-05-03 1979-11-29 C Koester Scanning microscopic apparatus
US4284897A (en) * 1977-04-30 1981-08-18 Olympus Optical Company Ltd. Fluorescence determining microscope utilizing laser light
GB2132852A (en) * 1982-12-11 1984-07-11 Zeiss Stiftung Method and apparatus for forming an image of the ocular fundus
GB2152697A (en) * 1983-10-25 1985-08-07 Atomic Energy Authority Uk Improvements in or relating to scanning optical microscopes
EP0155247A2 (en) * 1984-03-15 1985-09-18 Molecular Dynamics A method for microphotometering microscope specimens

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1185839A (en) * 1966-08-10 1970-03-25 Leitz Ernst Gmbh Improvements in or relating to Devices for Optically Scanning Microscopic Objects
US4284897A (en) * 1977-04-30 1981-08-18 Olympus Optical Company Ltd. Fluorescence determining microscope utilizing laser light
WO1979001027A1 (en) * 1978-05-03 1979-11-29 C Koester Scanning microscopic apparatus
GB2132852A (en) * 1982-12-11 1984-07-11 Zeiss Stiftung Method and apparatus for forming an image of the ocular fundus
GB2152697A (en) * 1983-10-25 1985-08-07 Atomic Energy Authority Uk Improvements in or relating to scanning optical microscopes
EP0155247A2 (en) * 1984-03-15 1985-09-18 Molecular Dynamics A method for microphotometering microscope specimens

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6288782B1 (en) 1993-06-17 2001-09-11 Ultrapointe Corporation Method for characterizing defects on semiconductor wafers
US6661515B2 (en) 1993-06-17 2003-12-09 Kla-Tencor Corporation Method for characterizing defects on semiconductor wafers
US6148114A (en) 1996-11-27 2000-11-14 Ultrapointe Corporation Ring dilation and erosion techniques for digital image processing

Also Published As

Publication number Publication date
GB2184321A (en) 1987-06-17
GB8629923D0 (en) 1987-01-28
GB8531011D0 (en) 1986-01-29

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Legal Events

Date Code Title Description
PE20 Patent expired after termination of 20 years

Effective date: 20061214