GB2181542A - Bacteriophages as recognition and identification agents - Google Patents

Bacteriophages as recognition and identification agents

Info

Publication number
GB2181542A
GB2181542A GB08527324A GB8527324A GB2181542A GB 2181542 A GB2181542 A GB 2181542A GB 08527324 A GB08527324 A GB 08527324A GB 8527324 A GB8527324 A GB 8527324A GB 2181542 A GB2181542 A GB 2181542A
Authority
GB
United Kingdom
Prior art keywords
bacteriophages
recognition
identification
antibodies
agents
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
GB08527324A
Other versions
GB8527324D0 (en
Inventor
Marius Constantin Teodorescu
Alexandre Gaspar
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of GB8527324D0 publication Critical patent/GB8527324D0/en
Publication of GB2181542A publication Critical patent/GB2181542A/en
Withdrawn legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56983—Viruses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C12Q1/04—Determining presence or kind of microorganism; Use of selective media for testing antibiotics or bacteriocides; Compositions containing a chemical indicator therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/554—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being a biological cell or cell fragment, e.g. bacteria, yeast cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/585—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with a particulate label, e.g. coloured latex
    • G01N33/586—Liposomes, microcapsules or cells

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Virology (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Mycology (AREA)
  • Toxicology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

Bacteriophages are employed as agents for recognition and identification of molecules and cellular materials, using their ability to recognize their bacterial host, by coating them with antibodies or by selecting them to perform in a manner analogous to antibodies. Visibility for identification is effected by incorporating a fluorescent agent, a radioisotope, a metal, an enzyme, or other staining material. The method of this invention may be utilized in selected clinical procedures, and is adaptable to use in an assay kit.
GB08527324A 1984-03-19 1985-03-15 Bacteriophages as recognition and identification agents Withdrawn GB2181542A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US59113684A 1984-03-19 1984-03-19
PCT/US1985/000438 WO1985004189A1 (en) 1984-03-19 1985-03-15 Bacteriophages as recognition and identification agents

Publications (2)

Publication Number Publication Date
GB8527324D0 GB8527324D0 (en) 1985-12-11
GB2181542A true GB2181542A (en) 1987-04-23

Family

ID=24365204

Family Applications (1)

Application Number Title Priority Date Filing Date
GB08527324A Withdrawn GB2181542A (en) 1984-03-19 1985-03-15 Bacteriophages as recognition and identification agents

Country Status (7)

Country Link
EP (1) EP0175761A4 (en)
JP (1) JPS61501489A (en)
DE (1) DE3590116T1 (en)
GB (1) GB2181542A (en)
NL (1) NL8520062A (en)
SE (1) SE8505458L (en)
WO (1) WO1985004189A1 (en)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4746604A (en) * 1985-05-24 1988-05-24 Enzo Biochem, Inc. Specific binding assays utilizing a viable cell as a label
AU1043788A (en) * 1986-12-01 1988-06-30 Mcdonnell Douglas Corporation Method of identifying unknown organisms
JPH05219994A (en) * 1990-01-24 1993-08-31 Amoco Corp Signal producing part and method for its use
GB9326277D0 (en) * 1993-12-23 1994-02-23 Marconi Gec Ltd Labelling
JP3270722B2 (en) * 1996-09-27 2002-04-02 オルガノ株式会社 Bacteria detection method and detection device
IT1291913B1 (en) 1997-05-22 1999-01-21 Angeletti P Ist Richerche Bio METHOD INVOLVING THE USE OF BACTERIOPHAGES FOR THE DETECTION OF THE PRESENCE OF MOLECULES OF INTEREST IN BIOLOGICAL SAMPLES
NZ508724A (en) * 1998-06-04 2003-04-29 Microsens Biophage Ltd Analytical method using at least two viruses to detect a target material in a sample
EP1031630B1 (en) * 1999-02-22 2004-10-20 Matsushita Electric Industrial Co., Ltd. Method for detecting bacteria
WO2001009370A2 (en) * 1999-07-30 2001-02-08 Profos Ag Detection and identification of bacterial strains
ES2346424T3 (en) 2002-04-12 2010-10-15 Colorado School Of Mines PROCEDURE FOR DETECTION OF LOW CONCENTRATIONS OF A DIANA BACTERIA THAT USES PHAGOS TO INFECT BACTERIAL CELLS DIANA.
US8216780B2 (en) 2002-04-12 2012-07-10 Microphage (Tm) Incorporated Method for enhanced sensitivity in bacteriophage-based diagnostic assays
WO2006105414A2 (en) * 2005-03-31 2006-10-05 Colorado School Of Mines Apparatus and method for detecting microscopic organisms using microphage
WO2007035504A1 (en) * 2005-09-15 2007-03-29 Microphage Incorporated Method and apparatus for identification of microorganisms using bacteriophage
CA2690809A1 (en) 2007-06-15 2008-12-24 Microphage Incorporated Method of detection of microorganisms with enhanced bacteriophage amplification
US8697434B2 (en) 2008-01-11 2014-04-15 Colorado School Of Mines Detection of phage amplification by SERS nanoparticles
US9441204B2 (en) 2008-04-03 2016-09-13 Colorado School Of Mines Compositions and methods for detecting Yersinia pestis bacteria
FR2940318B1 (en) * 2008-12-22 2011-05-13 Centre Nat Rech Scient NEW BIOTRACTORS AND THEIR USES FOR THE CONTROL OF FILTRATION FACILITIES
MX2018000960A (en) * 2015-07-31 2018-07-06 Univ Pittsburgh Commonwealth Sys Higher Education Detection of bacteria using bacteriophage.

Citations (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3094466A (en) * 1959-07-15 1963-06-18 Warner Lambert Pharmaceutical Preparation for typing of staphylococci and process therefor
US3553310A (en) * 1967-12-28 1971-01-05 Miles Lab Immunologically reactive particles
US3562384A (en) * 1960-11-08 1971-02-09 Miles Lab Immunological indicator and test system
US3717705A (en) * 1969-01-16 1973-02-20 M Sela Protein-bacteriophage conjugates
US4104126A (en) * 1976-01-29 1978-08-01 Nichols Institute Of Endocrinology, Inc. Non-isotopic substrate assay employing bacteriolysis products
US4105598A (en) * 1975-11-24 1978-08-08 California Institute Of Technology Cell specific, variable density, polymer microspheres
US4189466A (en) * 1975-09-19 1980-02-19 Technical Research Affiliates, Inc. Detection of rheumatoid factor by antibody sensitized microbial particles
US4223005A (en) * 1979-02-15 1980-09-16 University Of Illinois Foundation Antibody coated bacteria
US4282315A (en) * 1979-09-13 1981-08-04 Corning Glass Works Preparation of enriched whole virus radioligand
US4298689A (en) * 1978-09-25 1981-11-03 Research Corporation Gonorrhea diagnostic test
US4347311A (en) * 1979-07-28 1982-08-31 MEDAC Gesellschaft fur Klinishce Spezialpraparate mbH Enzyme immunoassay for determining antigen specific antibodies and test kit for carrying out this assay
US4474877A (en) * 1980-09-19 1984-10-02 Research And Education Institute, Inc. Harbor - Ucla Medical Center Process for detection and measurement of viral specific immunoglobulins and article of manufacture therefor
US4508829A (en) * 1981-09-16 1985-04-02 Teva Pharmaceutical Industries Ltd. Method and kit for pregnancy detection
US4511662A (en) * 1982-06-18 1985-04-16 Bio-Rad Laboratories, Inc. Simultaneous assay for T and B lymphocyte populations and subpopulations

Patent Citations (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3094466A (en) * 1959-07-15 1963-06-18 Warner Lambert Pharmaceutical Preparation for typing of staphylococci and process therefor
US3562384A (en) * 1960-11-08 1971-02-09 Miles Lab Immunological indicator and test system
US3553310A (en) * 1967-12-28 1971-01-05 Miles Lab Immunologically reactive particles
US3717705A (en) * 1969-01-16 1973-02-20 M Sela Protein-bacteriophage conjugates
US4189466A (en) * 1975-09-19 1980-02-19 Technical Research Affiliates, Inc. Detection of rheumatoid factor by antibody sensitized microbial particles
US4105598A (en) * 1975-11-24 1978-08-08 California Institute Of Technology Cell specific, variable density, polymer microspheres
US4104126A (en) * 1976-01-29 1978-08-01 Nichols Institute Of Endocrinology, Inc. Non-isotopic substrate assay employing bacteriolysis products
US4298689A (en) * 1978-09-25 1981-11-03 Research Corporation Gonorrhea diagnostic test
US4223005A (en) * 1979-02-15 1980-09-16 University Of Illinois Foundation Antibody coated bacteria
US4347311A (en) * 1979-07-28 1982-08-31 MEDAC Gesellschaft fur Klinishce Spezialpraparate mbH Enzyme immunoassay for determining antigen specific antibodies and test kit for carrying out this assay
US4282315A (en) * 1979-09-13 1981-08-04 Corning Glass Works Preparation of enriched whole virus radioligand
US4474877A (en) * 1980-09-19 1984-10-02 Research And Education Institute, Inc. Harbor - Ucla Medical Center Process for detection and measurement of viral specific immunoglobulins and article of manufacture therefor
US4508829A (en) * 1981-09-16 1985-04-02 Teva Pharmaceutical Industries Ltd. Method and kit for pregnancy detection
US4511662A (en) * 1982-06-18 1985-04-16 Bio-Rad Laboratories, Inc. Simultaneous assay for T and B lymphocyte populations and subpopulations

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
N, MOLECULAR IMMUNOLOGY, VOLUME 17, ISSUED 1980, PAGES 395-401. *

Also Published As

Publication number Publication date
SE8505458D0 (en) 1985-11-19
WO1985004189A1 (en) 1985-09-26
DE3590116T1 (en) 1987-02-19
SE8505458L (en) 1985-11-19
NL8520062A (en) 1986-02-03
GB8527324D0 (en) 1985-12-11
EP0175761A1 (en) 1986-04-02
EP0175761A4 (en) 1986-09-24
JPS61501489A (en) 1986-07-24

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Legal Events

Date Code Title Description
WAP Application withdrawn, taken to be withdrawn or refused ** after publication under section 16(1)