GB2178738B - 1,4-dihydropyridine sulfone derivatives, processes for their preparation and pharmaceutical compositions comprising the same - Google Patents

1,4-dihydropyridine sulfone derivatives, processes for their preparation and pharmaceutical compositions comprising the same

Info

Publication number
GB2178738B
GB2178738B GB8615240A GB8615240A GB2178738B GB 2178738 B GB2178738 B GB 2178738B GB 8615240 A GB8615240 A GB 8615240A GB 8615240 A GB8615240 A GB 8615240A GB 2178738 B GB2178738 B GB 2178738B
Authority
GB
United Kingdom
Prior art keywords
dihydropyridine
processes
preparation
same
pharmaceutical compositions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
GB8615240A
Other versions
GB2178738A (en
GB8615240D0 (en
Inventor
Toshihiro Takahashi
Koichiro Hagihara
Yoshikuni Suzuki
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nisshin Seifun Group Inc
Original Assignee
Nisshin Seifun Group Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nisshin Seifun Group Inc filed Critical Nisshin Seifun Group Inc
Publication of GB8615240D0 publication Critical patent/GB8615240D0/en
Publication of GB2178738A publication Critical patent/GB2178738A/en
Application granted granted Critical
Publication of GB2178738B publication Critical patent/GB2178738B/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
    • C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyridine Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
GB8615240A 1985-06-24 1986-06-23 1,4-dihydropyridine sulfone derivatives, processes for their preparation and pharmaceutical compositions comprising the same Expired - Fee Related GB2178738B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP60135990A JPS61293972A (en) 1985-06-24 1985-06-24 1,4-dihydroxypyridinesulfone derivative and production thereof

Publications (3)

Publication Number Publication Date
GB8615240D0 GB8615240D0 (en) 1986-07-30
GB2178738A GB2178738A (en) 1987-02-18
GB2178738B true GB2178738B (en) 1990-02-28

Family

ID=15164617

Family Applications (2)

Application Number Title Priority Date Filing Date
GB8615240A Expired - Fee Related GB2178738B (en) 1985-06-24 1986-06-23 1,4-dihydropyridine sulfone derivatives, processes for their preparation and pharmaceutical compositions comprising the same
GB8824140A Expired - Fee Related GB2208648B (en) 1985-06-24 1988-10-14 Suphonyl butene derivatives and processes for their preparation

Family Applications After (1)

Application Number Title Priority Date Filing Date
GB8824140A Expired - Fee Related GB2208648B (en) 1985-06-24 1988-10-14 Suphonyl butene derivatives and processes for their preparation

Country Status (4)

Country Link
JP (1) JPS61293972A (en)
DE (1) DE3620632A1 (en)
FR (1) FR2588003B1 (en)
GB (2) GB2178738B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2207523T3 (en) 1999-06-14 2004-06-01 Ortho-Mcneil Pharmaceutical, Inc. DITIEPINO (6,5-b) PIRIDINE AND ASSOCIATED COMPOSITIONS AND PROCEDURES.
CA3105038A1 (en) * 2018-06-26 2020-01-02 Tsrl, Inc. Metabolically stable prodrugs

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2524277A1 (en) * 1974-06-04 1975-12-18 Ciba Geigy Ag NEW 1,4-DIHYDROPYRIDINE AND THE METHOD OF MANUFACTURING THEM
DE2616995A1 (en) * 1976-04-17 1977-10-27 Bayer Ag Sulphur substd. (1,4)-dihydro-pyridine derivs. - with circulatory activity, e.g. vasodilating and hypotensive effects
DE2639498A1 (en) * 1976-09-02 1978-03-09 Bayer Ag NEW SULFUR-CONTAINING AMINO-DIHYDROPYRIDINES, THE PROCESS FOR THEIR MANUFACTURING AND THEIR USE AS A MEDICINAL PRODUCT
DE2747513A1 (en) * 1977-10-22 1979-05-03 Bayer Ag DIHYDROPYRIDINE WITH SULFUR-CONTAINING ESTER GROUPS
EP0111453A1 (en) * 1982-12-10 1984-06-20 Ciba-Geigy Ag Amide derivatives
EP0212107A1 (en) * 1985-06-21 1987-03-04 F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft Esters of 1,4-dihydro-5-sulfamoyl nicotinic acid

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2616991A1 (en) * 1976-04-17 1977-10-27 Bayer Ag Thio-substd. dihydro-pyridine derivs. - coronary vasodilators and antihypertensives prepd. e.g. by reacting dicarbonyl cpds. with amines and thio-substd. ketones
US4523847A (en) * 1983-07-07 1985-06-18 International Business Machines Corporation Frequency modulation-polarization spectroscopy method and device for detecting spectral features
DE3501695A1 (en) * 1985-01-19 1986-07-24 Bayer Ag, 5090 Leverkusen USE OF SULFONYL DIHYDROPYRIDINE AS A MEDICINAL PRODUCT FOR TREATING ASTHMA

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2524277A1 (en) * 1974-06-04 1975-12-18 Ciba Geigy Ag NEW 1,4-DIHYDROPYRIDINE AND THE METHOD OF MANUFACTURING THEM
GB1464324A (en) * 1974-06-04 1977-02-09 Ciba Geigy Ag 1,4-dihydropyridines and ''ocesses for their manufacture
DE2616995A1 (en) * 1976-04-17 1977-10-27 Bayer Ag Sulphur substd. (1,4)-dihydro-pyridine derivs. - with circulatory activity, e.g. vasodilating and hypotensive effects
DE2639498A1 (en) * 1976-09-02 1978-03-09 Bayer Ag NEW SULFUR-CONTAINING AMINO-DIHYDROPYRIDINES, THE PROCESS FOR THEIR MANUFACTURING AND THEIR USE AS A MEDICINAL PRODUCT
DE2747513A1 (en) * 1977-10-22 1979-05-03 Bayer Ag DIHYDROPYRIDINE WITH SULFUR-CONTAINING ESTER GROUPS
EP0001769A1 (en) * 1977-10-22 1979-05-16 Bayer Ag Sulfur-containing esters of 1,4-dihydropyridine carboxylic acids, their preparation and pharmaceutical use
EP0111453A1 (en) * 1982-12-10 1984-06-20 Ciba-Geigy Ag Amide derivatives
EP0212107A1 (en) * 1985-06-21 1987-03-04 F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft Esters of 1,4-dihydro-5-sulfamoyl nicotinic acid

Also Published As

Publication number Publication date
JPS61293972A (en) 1986-12-24
GB2178738A (en) 1987-02-18
FR2588003A1 (en) 1987-04-03
GB2208648A (en) 1989-04-12
GB2208648B (en) 1990-03-07
DE3620632A1 (en) 1987-01-02
GB8824140D0 (en) 1988-11-23
FR2588003B1 (en) 1989-09-15
GB8615240D0 (en) 1986-07-30

Similar Documents

Publication Publication Date Title
NZ212895A (en) 1,4-dihydropyridine derivatives and pharmaceutical compositions
HK18194A (en) Substituted benzamide derivatives,processes for the preparation thereof,and pharmaceutical compositions containing the same
EP0161877A3 (en) 1,4-dihydropyridine derivatives, methods for their production and pharmaceutical compositions comprising the same
NZ222030A (en) Substituted imidazo-(5,4-g (3,1 benzoxaminone derivatives and pharmaceutical compositions
IL76366A (en) 2,6-dialkyl-4-aryl-3,5-diacyl-1,4-dihydropyridine derivatives,processes for their manufacture and pharmaceutical preparations containing them
IL83413A0 (en) 1,4-dihydropyridine derivatives,their preparation and pharmaceutical compositions containing them
IL84913A0 (en) Alkanesulfonanilide derivatives,processes for preparation thereof and pharmaceutical composition comprising the same
IL75943A0 (en) 1,4-dihydropyridine derivatives,their preparation and pharmaceutical compositions containing them
IL88903A (en) Indolylpiperidine derivatives, processes for the preparation thereof and pharmaceutical compositions containing the same
ZA862141B (en) Substituted 1,8-naphthyridinones,processes for their preparation and pharmaceutical compositions containing them
DE3664774D1 (en) Novel 1,8-naphthyridine derivatives and processes for preparation thereof
NZ226516A (en) 2,2 dimethylchromene derivatives and pharmaceutical compositions
IL78576A0 (en) 5-pyrimidinecarboxamide,processes for the preparation thereof and pharmaceutical compositions containing same
IL87563A (en) Isoxazole-b-carboline derivatives, processes for the preparation thereof and pharmaceutical compositions containing the same
IL80658A0 (en) 6,7,8,9-tetrahydro-10-methyl-pyrido(1,2-a)indol-9-amines and derivatives thereof,their preparation and pharmaceutical compositions containing them
ZA86301B (en) 1,4-dihydropyridine derivatives,their preparation and pharmaceutical compositions containing them
NZ216555A (en) 1,4-dihydropyridine derivatives and pharmaceutical compositions
PT84339A (en) 1,6-NAPHTHYRIDINE DERIVATIVES PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
EP0184841A3 (en) 1,4-dihydropyridine derivatives, processes for their preparation and pharmaceutical compositions containing same
NZ218087A (en) 5-aryl-2,4-dialkyl-3h-1,2,4-triazole-3-thiones and pharmaceutical compositions
IL82294A (en) 1,4-dihydropyridine derivatives,processes for the preparation thereof and pharmaceutical compositions containing the same
GB2179347B (en) Methylenedioxyphenanthrene and -stilbene derivatives, processes for the preparation thereof and pharmaceutical compositions containing them
NZ215083A (en) 1,4-dihydropyridine derivatives and pharmaceutical compositions
GB2178738B (en) 1,4-dihydropyridine sulfone derivatives, processes for their preparation and pharmaceutical compositions comprising the same
ZA861074B (en) Novel 1,8-naphthyridine derivatives and processes for preparation thereof

Legal Events

Date Code Title Description
PCNP Patent ceased through non-payment of renewal fee

Effective date: 20040623