GB2159519B - 7-oxo-4-thia-1-azabicyclo3,2,0heptane derivatives; azetidinones - Google Patents

7-oxo-4-thia-1-azabicyclo3,2,0heptane derivatives; azetidinones

Info

Publication number
GB2159519B
GB2159519B GB08516150A GB8516150A GB2159519B GB 2159519 B GB2159519 B GB 2159519B GB 08516150 A GB08516150 A GB 08516150A GB 8516150 A GB8516150 A GB 8516150A GB 2159519 B GB2159519 B GB 2159519B
Authority
GB
United Kingdom
Prior art keywords
0heptane
azetidinones
thia
oxo
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB08516150A
Other versions
GB8516150D0 (en
GB2159519A (en
Inventor
Barry Clive Ross
Graham Johnson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis UK Holdings Ltd
Original Assignee
Hoechst UK Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB08308276A external-priority patent/GB2118546B/en
Application filed by Hoechst UK Ltd filed Critical Hoechst UK Ltd
Publication of GB8516150D0 publication Critical patent/GB8516150D0/en
Publication of GB2159519A publication Critical patent/GB2159519A/en
Application granted granted Critical
Publication of GB2159519B publication Critical patent/GB2159519B/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
    • C07D205/09—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams with a sulfur atom directly attached in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D499/88—Compounds with a double bond between positions 2 and 3 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804—Compounds having Si-O-C linkages

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
GB08516150A 1982-03-26 1985-06-26 7-oxo-4-thia-1-azabicyclo3,2,0heptane derivatives; azetidinones Expired GB2159519B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB8208983 1982-03-26
GB08308276A GB2118546B (en) 1982-03-26 1983-03-25 7-oxo-4-thia-1-azabicyclo(3,2,0)heptane derivatives

Publications (3)

Publication Number Publication Date
GB8516150D0 GB8516150D0 (en) 1985-07-31
GB2159519A GB2159519A (en) 1985-12-04
GB2159519B true GB2159519B (en) 1986-08-20

Family

ID=26282384

Family Applications (1)

Application Number Title Priority Date Filing Date
GB08516150A Expired GB2159519B (en) 1982-03-26 1985-06-26 7-oxo-4-thia-1-azabicyclo3,2,0heptane derivatives; azetidinones

Country Status (1)

Country Link
GB (1) GB2159519B (en)

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE8101464L (en) * 1980-03-10 1981-09-11 Sankyo Co 2-PENEM-3-CARBOXYLIC ACID DERIVATIVES, THEIR PREPARATION AND USE
ATE21105T1 (en) * 1980-11-06 1986-08-15 Hoechst Uk Ltd 7-OXO-4-THIA-1-AZA(3.2.0)HEPTANE AND 7-OXO-4-THIA-1-AZA-(3.2.0)HEPT-2-EN DERIVATIVES.
DE3382761T2 (en) * 1982-11-29 1995-03-09 Schering Corp Process for the production of penem compounds.
EP0115308A3 (en) * 1983-01-25 1984-10-10 Merck & Co. Inc. 2-unsaturated alkylthio-pen-2-em-3-carboxylic acids and process for preparing substituted 2-thioxopenams and 2-substituted thiopenems

Also Published As

Publication number Publication date
GB8516150D0 (en) 1985-07-31
GB2159519A (en) 1985-12-04

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Legal Events

Date Code Title Description
PCNP Patent ceased through non-payment of renewal fee