GB2147206B - Proteolytic enzyme treatment of wounds - Google Patents

Proteolytic enzyme treatment of wounds

Info

Publication number
GB2147206B
GB2147206B GB08423913A GB8423913A GB2147206B GB 2147206 B GB2147206 B GB 2147206B GB 08423913 A GB08423913 A GB 08423913A GB 8423913 A GB8423913 A GB 8423913A GB 2147206 B GB2147206 B GB 2147206B
Authority
GB
United Kingdom
Prior art keywords
wounds
proteolytic enzyme
enzyme treatment
treatment
proteolytic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB08423913A
Other versions
GB8423913D0 (en
GB2147206A (en
Inventor
Jaroslava Turkova
Jiri Stamberg
Vladimir Pitrak
Lenka Jelinkova
Karel Sebesta
Mojmir Sebestik
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Czech Academy of Sciences CAS
Original Assignee
Czech Academy of Sciences CAS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Czech Academy of Sciences CAS filed Critical Czech Academy of Sciences CAS
Publication of GB8423913D0 publication Critical patent/GB8423913D0/en
Publication of GB2147206A publication Critical patent/GB2147206A/en
Application granted granted Critical
Publication of GB2147206B publication Critical patent/GB2147206B/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
    • C12N11/02—Enzymes or microbial cells immobilised on or in an organic carrier
    • C12N11/10—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a carbohydrate
    • C12N11/12—Cellulose or derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/482—Serine endopeptidases (3.4.21)
    • A61K38/4826—Trypsin (3.4.21.4) Chymotrypsin (3.4.21.1)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0009—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing macromolecular materials
    • A61L26/0023—Polysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0057—Ingredients of undetermined constitution or reaction products thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0061—Use of materials characterised by their function or physical properties
    • A61L26/0066—Medicaments; Biocides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
    • A61L2300/252—Polypeptides, proteins, e.g. glycoproteins, lipoproteins, cytokines
    • A61L2300/254—Enzymes, proenzymes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Materials Engineering (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Microbiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
GB08423913A 1983-09-29 1984-09-21 Proteolytic enzyme treatment of wounds Expired GB2147206B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CS713883A CS249311B1 (en) 1983-09-29 1983-09-29 Proteolytic wound dressing

Publications (3)

Publication Number Publication Date
GB8423913D0 GB8423913D0 (en) 1984-10-31
GB2147206A GB2147206A (en) 1985-05-09
GB2147206B true GB2147206B (en) 1988-01-27

Family

ID=5419947

Family Applications (1)

Application Number Title Priority Date Filing Date
GB08423913A Expired GB2147206B (en) 1983-09-29 1984-09-21 Proteolytic enzyme treatment of wounds

Country Status (9)

Country Link
JP (1) JPS6094916A (en)
CA (1) CA1217134A (en)
CS (1) CS249311B1 (en)
DD (1) DD258121A3 (en)
DE (1) DE3435718A1 (en)
FR (1) FR2552667B1 (en)
GB (1) GB2147206B (en)
HU (1) HUT35956A (en)
SE (1) SE8404769L (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6600057B2 (en) 2000-12-29 2003-07-29 Kimberly-Clark Worldwide, Inc. Matrix metalloproteinase inhibitors

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3606265A1 (en) * 1986-02-27 1987-09-03 Roehm Pharma Gmbh POLYSACCHARID-BASED Wound Dressing As a Carrier Therapeutically Effective, Non-Immobilized Enzymes and with High Absorbency
FR2600897A1 (en) * 1986-07-04 1988-01-08 Pf Medicament Proteolytic and absorbent dressing and process for its preparation
CZ277766B6 (en) * 1990-01-04 1993-04-14 Vnii Textilno Biologically active material and process for preparing thereof
EP0498532A1 (en) * 1991-01-10 1992-08-12 E.R. SQUIBB & SONS, INC. Necrotic tissue debridement powder composition containing a proteolytic enzyme
IL104734A0 (en) * 1993-02-15 1993-06-10 Univ Bar Ilan Bioactive conjugates of cellulose with amino compounds
DE19813663A1 (en) * 1998-03-27 1999-10-07 Beiersdorf Ag Wound dressings for removing disruptive factors from wound fluid
US7041787B2 (en) 2000-12-29 2006-05-09 Kimberly-Clark Worldwide, Inc. Design and use of advanced zinc chelating peptides to regulate matrix metalloproteinases
RU2213557C2 (en) 2001-12-26 2003-10-10 Закрытое акционерное общество "Аксис" Pharmaceutical composition eliciting thrombolytic, anti-inflammatory and cytoprotective properties
AU2003212195A1 (en) * 2002-02-06 2003-09-02 N-Zyme Biotec Gmbh Protease screening and novel use of proteases
US20030198631A1 (en) * 2002-04-18 2003-10-23 Healthpoint, Ltd. Thermolysin enzymatic wound debrider
US7928282B2 (en) * 2004-04-30 2011-04-19 Kimberly-Clark Worldwide, Inc. Absorbent products with a linked enzyme treatment
IT1395129B1 (en) 2009-07-30 2012-09-05 Franzoni Filati S P A AMINOGLICOSIDES AND PREGELATINIZED AMINOGLYCOSIDES COVALENTLY COMBINED WITH COTTON
US11446364B2 (en) 2012-11-14 2022-09-20 Smith & Nephew, Inc. Stable thermolysin hydrogel
US11452698B2 (en) 2013-03-15 2022-09-27 Smith & Nephew, Inc. Dissolvable gel-forming film for delivery of active agents

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RO57973A (en) * 1969-06-13 1975-03-15
DE1938189A1 (en) * 1969-07-28 1971-02-25 Blendax Werke Schneider Co Dental and oral care products containing enzymes
FR2488797A1 (en) * 1980-08-19 1982-02-26 Lhd Lab Hygiene Dietetique DERMATOLOGICAL COMPOSITION, PROCESS FOR PREPARATION AND APPLICATION IN THE FIELD OF DRESSINGS

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6600057B2 (en) 2000-12-29 2003-07-29 Kimberly-Clark Worldwide, Inc. Matrix metalloproteinase inhibitors

Also Published As

Publication number Publication date
HUT35956A (en) 1985-08-28
SE8404769D0 (en) 1984-09-24
FR2552667B1 (en) 1987-11-27
SE8404769L (en) 1985-03-30
JPS6094916A (en) 1985-05-28
CS249311B1 (en) 1987-03-12
DD258121A3 (en) 1988-07-13
GB8423913D0 (en) 1984-10-31
FR2552667A1 (en) 1985-04-05
GB2147206A (en) 1985-05-09
CA1217134A (en) 1987-01-27
DE3435718A1 (en) 1985-04-11

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Legal Events

Date Code Title Description
PCNP Patent ceased through non-payment of renewal fee