GB2137526A - Vial sleeve - Google Patents
Vial sleeve Download PDFInfo
- Publication number
- GB2137526A GB2137526A GB08308378A GB8308378A GB2137526A GB 2137526 A GB2137526 A GB 2137526A GB 08308378 A GB08308378 A GB 08308378A GB 8308378 A GB8308378 A GB 8308378A GB 2137526 A GB2137526 A GB 2137526A
- Authority
- GB
- United Kingdom
- Prior art keywords
- vial
- sleeve
- vials
- supporting
- locating
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L9/00—Supporting devices; Holding devices
- B01L9/06—Test-tube stands; Test-tube holders
Landscapes
- Health & Medical Sciences (AREA)
- Clinical Laboratory Science (AREA)
- Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Automatic Analysis And Handling Materials Therefor (AREA)
- Devices For Use In Laboratory Experiments (AREA)
- Sampling And Sample Adjustment (AREA)
Abstract
Automatic sampling facilities (autosamplers) for chromographs and spectrophotometers employ a carousel arrangement for supporting a plurality of different vials each of predetermined size to bring each vial into a sampling position. Where sample quantities are small, narrower vials are used to enable efficient extraction of the samples from the vial. Such narrower vials cannot be supported by the autosampler without considerable adaptation thereto. Instead vial locating and supporting sleeves are used to enable such narrower vials to be accepted by the autosampler.
Description
1 GB 2 137 526 A 1
SPECIFICATION
Vial sleeve The present invention relates to locating and supporting sleeves for vials, and in particular to sleeves of a certain shape and size for locating and supporting vials in analytical instruments.
In the analytical sciences it has become increas- ingly commonplace to use instruments with automa tic sampling facilities (autosamplers), e.g. with chromatographs or spectrophotometers. Such facilities usually take the form of a carousel armagement in which vials containing samples for examination are located around the periphery of the carousel. Thus samples may be separately presented for analysis on rotation of the carousel.
A known disadvantage of such autosamplers is that it is not normally possible for a needle, probe or other extraction device to remove all of the sample from any given via] in the sampler. In some instances, due to the size of the gap between the bottom of the vial and the extraction device, the amount of available sample is simply too small for withdrawal.
In cases where an adequate volume of sample is available the existence of a gap between the bottom of the vial and the extraction device presents no problem, but many laboratories, especially those in hospitals, frequently have to accept inadequate sample volumes for examination, and difficulties may then arise.
Thus, there is a clear need to provide a low volume vial which is sufficiently narrow to cause displacement of the sample contents when an extraction device enters the vial, enabling small quantities to be extracted from small sample volumes. Preferably, the vial also has an external convex- shaped bottom.
Unfortunately, vials meeting these requirements have been found to be too narrow to fit into typical autosampler devices.
Thus, the present invention provides a precision locating and supporting sleeve for a vial which enables the user to fit the vial accurately into a variety of different autosamplers.
Accordingly, the present invention provides a cylindrical, vial locating and supporting sleeve with a coaxial cylindrical bore in which the ratio of the height of the sleeve to its outside diameter is in the range of 1. 5 to 4.5 and the ratio of the outside diameter of the sleeve to the inside diameter is in the 115 range of 1.5 to 2.75.
The present invention also provides a combination of the sleeve defined in the previous paragraph and a vial when located and supported by the sleeve.
Preferably, the material of the vial sleeve is poly-tetra-fluoro-ethylene (PTFE), though other suitable materials such as other plastics, glass, wood, metal, may also be used.
The bore of the vial sleeve is desirably open at both ends, though it may be closed at one end in some instances.
Advantageously, the vials have a cylindrical collar of slightly greater diameter than their cylindrical body primarily to provide means for receiving a crimped-on cap to seal the vial. However, in the present invention the collar also acts to prevent the vial from "completely" entering the locating sleeve, which may make it difficult subsequently to remove the vial. In some cases the bore of the sleeve may be partially widened at its entrance to accommodate the collar portion.
Typically, a support sleeve has a height of between 25 and 40 mm, an outside diameter of between 9 and 15 mm and an inside diameter of 5.8 mm. A typical preferred vial of borosilicate glass with a convex end portion has a length of 32 mm, an outside diameter of 5.6 mm and a collar of 7 mm diameter, thus providing a firm and positive fit within a locating a supporting sleeve. A vial of these dimensions would have a liquid capacity of approximately 0.3 mi.
Amongst commercially available autosamplers in which a vial sleeve according to the present invention may readily be used are those manufactured by Beckman Instruments Inc of Fullerton, California, USA; Dani SpA of Monza, Italy; Kontron AG of Zurich, Switzerland; Magnus Scientific Limited of Milton Keynes, Bucks, England; Perkin-Elmer Corporation of Norwalk, Conneticut, USA; Precision Sampling Company of Baton Rouge, Louisiana, USA; Pye Unican Limited of Cambridge, England; Spectra-Physics Inc of San Jose, California, USA and Varian Associates Inc of Palo Alto, California, USA.
Claims (10)
1. A precision locating and supporting sleeve for a vial which enables the user to fit the vial accurately into a variety of different autosamplers.
2. A cylindrical, vial locating and supporting sleeve with a coaxial cylindrical bore in which the ratio of the height of the sleeve to its outside diameter is in the range of 1.5 to 4.5 and the ratio of the outside diameter of the sleeve to the inside diameter is in the range 1.5 to 2.75.
3. A sleeve according to Claim 1 orto Claim 2 wherein the bore of the sleeve is open at both ends.
4. Asleeve according to Claim 1 orto Claim 2 wherein the bore of the sleeve is closed at one end.
5. A combination of a sleeve according to Claim 1 or to Claim 2 and a vial located and supported by the sleeve.
6. A combination according to Claim 5 wherein the vial has a cylindrical collar of slightly greater diameter than its cylindrical body which provides means for receiving a crimped-on cap to seal the vial.
7. A combination according to Claim 6 wherein the bore of the sleeve is partially widened at its entrance to accommodate the collar of the vial.
8. An autosampler for accepting vials of predetermined size in combination with a kit comprising a plurality of vials of smaller sizes and a plurality of vial supporting sleeves for locating and supporting the different smaller sized vials, each sleeve having an external diameter substantially equal to that of said vials of predetermined size and an internal diameter sized to accommodate a corresponding one of said smaller sized vials.
9. A precision locating and supporting sleeve for 2 GB 2 137 526 A 2 a vial substantially as hereinbefore specifically described.
10. A combination of a precision vial locating and supporting sleeve and a vial supported by the sleeve substantially as hereinbefore specifically described.
Printed in the UK for HMSO, D8818935,8184,7102. Published by The Patent Office, 25 Southampton Buildings, London, WC2A lAY, from which copies may be obtained.
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Priority Applications (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB08308378A GB2137526B (en) | 1983-03-26 | 1983-03-26 | Vial sleeve |
US07/108,670 US5116578A (en) | 1983-03-26 | 1987-10-15 | Vial sleeve |
HK1066/88A HK106688A (en) | 1983-03-26 | 1988-12-29 | Vial sleeve device |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB08308378A GB2137526B (en) | 1983-03-26 | 1983-03-26 | Vial sleeve |
Publications (3)
Publication Number | Publication Date |
---|---|
GB8308378D0 GB8308378D0 (en) | 1983-05-05 |
GB2137526A true GB2137526A (en) | 1984-10-10 |
GB2137526B GB2137526B (en) | 1987-10-07 |
Family
ID=10540282
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB08308378A Expired GB2137526B (en) | 1983-03-26 | 1983-03-26 | Vial sleeve |
Country Status (3)
Country | Link |
---|---|
US (1) | US5116578A (en) |
GB (1) | GB2137526B (en) |
HK (1) | HK106688A (en) |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3732767A1 (en) * | 1987-09-25 | 1989-04-06 | Baxter | DEVICES AND METHODS |
EP0444498A2 (en) * | 1990-02-28 | 1991-09-04 | The Perkin-Elmer Corporation | Vial locator and sensor |
US5171530A (en) * | 1990-02-28 | 1992-12-15 | The Perkin-Elmer Corporation | Vial locator and sensor |
Families Citing this family (30)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2076370A1 (en) * | 1990-03-02 | 1991-09-03 | Thomas B. Green | Analyzer transport device |
GB9107258D0 (en) * | 1991-04-06 | 1991-05-22 | Chromacol Ltd | Apparatus for use in analytical instruments |
US5376313A (en) | 1992-03-27 | 1994-12-27 | Abbott Laboratories | Injection molding a plastic assay cuvette having low birefringence |
US5605665A (en) | 1992-03-27 | 1997-02-25 | Abbott Laboratories | Reaction vessel |
US5635364A (en) | 1992-03-27 | 1997-06-03 | Abbott Laboratories | Assay verification control for an automated analytical system |
US5575978A (en) | 1992-03-27 | 1996-11-19 | Abbott Laboratories | Sample container segment assembly |
US5960160A (en) | 1992-03-27 | 1999-09-28 | Abbott Laboratories | Liquid heater assembly with a pair temperature controlled electric heating elements and a coiled tube therebetween |
US5507410A (en) | 1992-03-27 | 1996-04-16 | Abbott Laboratories | Meia cartridge feeder |
US5540890A (en) | 1992-03-27 | 1996-07-30 | Abbott Laboratories | Capped-closure for a container |
US5578494A (en) | 1992-03-27 | 1996-11-26 | Abbott Laboratories | Cap actuator for opening and closing a container |
US5646049A (en) | 1992-03-27 | 1997-07-08 | Abbott Laboratories | Scheduling operation of an automated analytical system |
US5627522A (en) | 1992-03-27 | 1997-05-06 | Abbott Laboratories | Automated liquid level sensing system |
EP1380843A3 (en) * | 1992-03-27 | 2010-01-13 | Abbott Laboratories | Automated liquid level sensing device |
US5610069A (en) | 1992-03-27 | 1997-03-11 | Abbott Laboratories | Apparatus and method for washing clinical apparatus |
US6190617B1 (en) | 1992-03-27 | 2001-02-20 | Abbott Laboratories | Sample container segment assembly |
US5536471A (en) | 1992-03-27 | 1996-07-16 | Abbott Laboratories | Syringe with bubble flushing |
WO1995023328A1 (en) * | 1994-02-28 | 1995-08-31 | The Cardinal Instrument Company | Sample preparation and metering system |
US5856653A (en) * | 1996-06-13 | 1999-01-05 | Boudreaux; Nona | Mascara extender |
DE19826470C2 (en) | 1998-06-13 | 2001-10-18 | Eppendorf Ag | Cuvette system and cuvette |
US20020121139A1 (en) * | 2001-03-02 | 2002-09-05 | Purpura Paul E. | Adapter for holding a sample container to facilitate sensing of liquid level in the sample container |
EP1508375A3 (en) * | 2003-08-19 | 2006-04-05 | Fuji Photo Film Co., Ltd. | Rack for extracting apparatuses |
US7676976B2 (en) * | 2003-11-06 | 2010-03-16 | Surefire, Llc | Systems for attaching a noise suppressor to a firearm |
US7178414B1 (en) | 2004-02-27 | 2007-02-20 | Kokosa John M | Automation of liquid phase microextraction |
US8357538B2 (en) * | 2007-04-06 | 2013-01-22 | Qiagen Gaithersburg, Inc. | Automated assay and system |
US8703492B2 (en) | 2007-04-06 | 2014-04-22 | Qiagen Gaithersburg, Inc. | Open platform hybrid manual-automated sample processing system |
US8839970B2 (en) * | 2008-10-09 | 2014-09-23 | Waters Technologies Corporation | Devices for containing materials and methods of using and making same |
WO2011063139A1 (en) | 2009-11-18 | 2011-05-26 | Qiagen | Laboratory central control unit method and system |
US9891149B2 (en) | 2011-08-08 | 2018-02-13 | Thermo Fisher Scientific Oy | Method and apparatus for automated analysis |
FI20115785A0 (en) * | 2011-08-08 | 2011-08-08 | Thermo Fisher Scientific Oy | Method and apparatus for automatic analysis |
US11602486B2 (en) | 2021-06-29 | 2023-03-14 | Daniel Singh | Device for chilling insulin in a travel mug |
Citations (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1290957A (en) * | 1969-03-26 | 1972-09-27 | ||
GB1323512A (en) * | 1970-09-14 | 1973-07-18 | Technicon Instr | Sample container |
US3918920A (en) * | 1974-01-07 | 1975-11-11 | Beckman Instruments Inc | Holder for sample containers of different sizes |
GB1416756A (en) * | 1972-09-27 | 1975-12-03 | Searle & Co | Sample tray insert |
GB1423185A (en) * | 1972-09-27 | 1976-01-28 | Bancsich J Hadrian W | Specimen holder and arrangement for registration and read out thereof |
GB1473042A (en) * | 1974-04-01 | 1977-05-11 | Commissariat Energie Atomique | Device for automatic analysis |
US4043762A (en) * | 1976-10-06 | 1977-08-23 | George Milton Olds | Coupling means for test tubes and the like |
GB1545163A (en) * | 1976-08-30 | 1979-05-02 | Mallinckrodt Inc | Coated tube for immunochemical and enzymatic assays |
GB2101007A (en) * | 1981-07-06 | 1983-01-12 | Medizin Labortechnik Veb K | Laboratory vessel supports |
EP0069180A1 (en) * | 1981-07-06 | 1983-01-12 | Robert Joseph Miskinis | Laboratory stopper for glassware |
Family Cites Families (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3027799A (en) * | 1959-01-26 | 1962-04-03 | Brunswick Corp | Sample space adapters for spectrophotometers and the like |
US3615239A (en) * | 1969-03-12 | 1971-10-26 | American Hospital Supply Corp | Automated analyzer and programmer therefor |
US3916157A (en) * | 1970-09-08 | 1975-10-28 | Mmbi Inc | Specimen carrier |
US3807955A (en) * | 1971-04-15 | 1974-04-30 | Becton Dickinson Co | Serum/plasma isolator cup |
US4000976A (en) * | 1972-12-07 | 1977-01-04 | G. D. Searle & Co. | Apparatus and method for preparing, diluting and replicating laboratory samples |
US3938735A (en) * | 1975-03-13 | 1976-02-17 | Beckman Instruments, Inc. | Capping assembly for thin all centrifuge tubes |
GB1561061A (en) * | 1976-03-17 | 1980-02-13 | Hycel Inc | Reaction conveyor assembly in an automatic chemical testing apparatus |
US4094641A (en) * | 1977-02-25 | 1978-06-13 | Waters Associates, Inc. | Low loss sample bottle assembly |
US4208484A (en) * | 1977-03-22 | 1980-06-17 | Olympus Optical Co., Ltd. | Apparatus for handling centrifuge tubes in automatic culture system |
US4256697A (en) * | 1978-12-21 | 1981-03-17 | Fred Baldwin | Blood incubator device |
US4278437A (en) * | 1979-04-09 | 1981-07-14 | Jan Haggar | Fluid specimen holder for biological fluid testing |
CH647184A5 (en) * | 1980-08-15 | 1985-01-15 | Reishauer Ag | PALLET FOR TRANSPORTING AND STORING WORKPIECES. |
US4483616A (en) * | 1981-07-20 | 1984-11-20 | American Hospital Supply Corporation | Container for small quantities of liquids |
-
1983
- 1983-03-26 GB GB08308378A patent/GB2137526B/en not_active Expired
-
1987
- 1987-10-15 US US07/108,670 patent/US5116578A/en not_active Expired - Lifetime
-
1988
- 1988-12-29 HK HK1066/88A patent/HK106688A/en not_active IP Right Cessation
Patent Citations (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1290957A (en) * | 1969-03-26 | 1972-09-27 | ||
GB1323512A (en) * | 1970-09-14 | 1973-07-18 | Technicon Instr | Sample container |
GB1416756A (en) * | 1972-09-27 | 1975-12-03 | Searle & Co | Sample tray insert |
GB1423185A (en) * | 1972-09-27 | 1976-01-28 | Bancsich J Hadrian W | Specimen holder and arrangement for registration and read out thereof |
US3918920A (en) * | 1974-01-07 | 1975-11-11 | Beckman Instruments Inc | Holder for sample containers of different sizes |
GB1473042A (en) * | 1974-04-01 | 1977-05-11 | Commissariat Energie Atomique | Device for automatic analysis |
GB1545163A (en) * | 1976-08-30 | 1979-05-02 | Mallinckrodt Inc | Coated tube for immunochemical and enzymatic assays |
US4043762A (en) * | 1976-10-06 | 1977-08-23 | George Milton Olds | Coupling means for test tubes and the like |
GB2101007A (en) * | 1981-07-06 | 1983-01-12 | Medizin Labortechnik Veb K | Laboratory vessel supports |
EP0069180A1 (en) * | 1981-07-06 | 1983-01-12 | Robert Joseph Miskinis | Laboratory stopper for glassware |
Cited By (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3732767A1 (en) * | 1987-09-25 | 1989-04-06 | Baxter | DEVICES AND METHODS |
GB2210456A (en) * | 1987-09-25 | 1989-06-07 | James Alexander Baxter | Sleeve for locating a vial in an autosampler |
GB2210456B (en) * | 1987-09-25 | 1991-07-31 | James Alexander Baxter | Sleeve for locating and supporting vials in autosamplers |
EP0444498A2 (en) * | 1990-02-28 | 1991-09-04 | The Perkin-Elmer Corporation | Vial locator and sensor |
EP0444498A3 (en) * | 1990-02-28 | 1992-03-18 | The Perkin-Elmer Corporation | Vial locator and sensor |
US5171530A (en) * | 1990-02-28 | 1992-12-15 | The Perkin-Elmer Corporation | Vial locator and sensor |
AU640453B2 (en) * | 1990-02-28 | 1993-08-26 | Perkin-Elmer Corporation, The | Apparatus for automatically locating vials in an analytical instrument |
Also Published As
Publication number | Publication date |
---|---|
GB2137526B (en) | 1987-10-07 |
GB8308378D0 (en) | 1983-05-05 |
US5116578A (en) | 1992-05-26 |
HK106688A (en) | 1989-01-06 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
732 | Registration of transactions, instruments or events in the register (sect. 32/1977) | ||
PE20 | Patent expired after termination of 20 years |
Effective date: 20030325 |