GB2121802B - Benzo-fused carbacyclin analogues - Google Patents

Benzo-fused carbacyclin analogues

Info

Publication number
GB2121802B
GB2121802B GB08319029A GB8319029A GB2121802B GB 2121802 B GB2121802 B GB 2121802B GB 08319029 A GB08319029 A GB 08319029A GB 8319029 A GB8319029 A GB 8319029A GB 2121802 B GB2121802 B GB 2121802B
Authority
GB
United Kingdom
Prior art keywords
benzo
fused
carbacyclin analogues
carbacyclin
analogues
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB08319029A
Other versions
GB8319029D0 (en
GB2121802A (en
Inventor
Paul Adrian Aristoff
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pharmacia and Upjohn Co
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Publication of GB8319029D0 publication Critical patent/GB8319029D0/en
Publication of GB2121802A publication Critical patent/GB2121802A/en
Application granted granted Critical
Publication of GB2121802B publication Critical patent/GB2121802B/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C07C405/005—Analogues or derivatives having the five membered ring replaced by other rings
    • C07C405/0075—Analogues or derivatives having the five membered ring replaced by other rings having the side-chains or their analogues or derivatives attached to a condensed ring system
    • C07C405/0083—Analogues or derivatives having the five membered ring replaced by other rings having the side-chains or their analogues or derivatives attached to a condensed ring system which is only ortho or peri condensed, e.g. carbacyclins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/10—Oxygen atoms
    • C07D309/12—Oxygen atoms only hydrogen atoms and one oxygen atom directly attached to ring carbon atoms, e.g. tetrahydropyranyl ethers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804—Compounds having Si-O-C linkages

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
GB08319029A 1980-03-28 1983-07-14 Benzo-fused carbacyclin analogues Expired GB2121802B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US13505580A 1980-03-28 1980-03-28

Publications (3)

Publication Number Publication Date
GB8319029D0 GB8319029D0 (en) 1983-08-17
GB2121802A GB2121802A (en) 1984-01-04
GB2121802B true GB2121802B (en) 1985-01-16

Family

ID=22466314

Family Applications (2)

Application Number Title Priority Date Filing Date
GB08319032A Expired GB2122203B (en) 1980-03-28 1983-07-14 Benzo-fused bicyclononanes
GB08319029A Expired GB2121802B (en) 1980-03-28 1983-07-14 Benzo-fused carbacyclin analogues

Family Applications Before (1)

Application Number Title Priority Date Filing Date
GB08319032A Expired GB2122203B (en) 1980-03-28 1983-07-14 Benzo-fused bicyclononanes

Country Status (1)

Country Link
GB (2) GB2122203B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1241324A (en) * 1984-03-08 1988-08-30 Paul A. Aristoff Interphenylene carbacyclin derivatives
CA2056039A1 (en) * 1991-01-22 1992-07-23 Philip L. Fuchs Carbacyclin analogs

Also Published As

Publication number Publication date
GB2122203B (en) 1985-01-03
GB8319032D0 (en) 1983-08-17
GB2122203A (en) 1984-01-11
GB8319029D0 (en) 1983-08-17
GB2121802A (en) 1984-01-04

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Legal Events

Date Code Title Description
PE20 Patent expired after termination of 20 years

Effective date: 20010129