GB2101327A - Equipment for producing an nmr image as a planar projection - Google Patents
Equipment for producing an nmr image as a planar projection Download PDFInfo
- Publication number
- GB2101327A GB2101327A GB08134194A GB8134194A GB2101327A GB 2101327 A GB2101327 A GB 2101327A GB 08134194 A GB08134194 A GB 08134194A GB 8134194 A GB8134194 A GB 8134194A GB 2101327 A GB2101327 A GB 2101327A
- Authority
- GB
- United Kingdom
- Prior art keywords
- subject
- projection
- image
- equipment
- examination subject
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
- G01R33/00—Arrangements or instruments for measuring magnetic variables
- G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
- G01R33/44—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
- G01R33/48—NMR imaging systems
- G01R33/483—NMR imaging systems with selection of signals or spectra from particular regions of the volume, e.g. in vivo spectroscopy
- G01R33/4833—NMR imaging systems with selection of signals or spectra from particular regions of the volume, e.g. in vivo spectroscopy using spatially selective excitation of the volume of interest, e.g. selecting non-orthogonal or inclined slices
- G01R33/4835—NMR imaging systems with selection of signals or spectra from particular regions of the volume, e.g. in vivo spectroscopy using spatially selective excitation of the volume of interest, e.g. selecting non-orthogonal or inclined slices of multiple slices
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
- G01R33/00—Arrangements or instruments for measuring magnetic variables
- G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
- G01R33/28—Details of apparatus provided for in groups G01R33/44 - G01R33/64
Landscapes
- Physics & Mathematics (AREA)
- Condensed Matter Physics & Semiconductors (AREA)
- General Physics & Mathematics (AREA)
- Optics & Photonics (AREA)
- Spectroscopy & Molecular Physics (AREA)
- High Energy & Nuclear Physics (AREA)
- Magnetic Resonance Imaging Apparatus (AREA)
Abstract
In a system for imaging a subject 2 by means of nuclear magnetic resonance, and including means 3 for the application of magnetic fields to the subject and for detecting excursions of atomic nuclei of the subject from their state of equilibrium by a high-frequency magnetic excitation pulse, means 13, 17 control the image production so that the image produced represents a projection of at least part of the subject on to a prescribed plane 1. In this way complete pictures, corresponding to X-ray shadow images, are produced with the aid of nuclear magnetic resonance. As described, a magnetic field gradient defines a slice of the subject for projection, successive slices being selected by moving the subject or varying the frequency of the excitation pulse to build up the projection a line at a time. <IMAGE>
Description
SPECIFICATION
Equipment for producing an image of at least part of an examination subject
The present invention relates to equipment for producing an image of at least part of an examination subject by means of nuclear magnetic resonance. More particularly, the present invention relates to such equipment in which there are means for the application of magnetic fields on to the examination subject and for detecting the excursions of atomic nuclei of the examination subject from their state of equilibriun of a high-frequency magnetic excitation pulse.
It is known that hydrogen atomic nuclei, in particuiar, of an examination subject can be deflected from a preferred direction, which is produced by magnetic base field, by a highfrequency excitation pulse and that, when the excitation pulse ceases, there is a certain delay before the atomic nuclei level off into the preferred direction, as a result of their spin. During this delay, the atomic nuclei precess with a frequency determined by the strength of the magnetic base field. If a field gradient is superimposed on this uniform magnetic base field so that the magnetic field distribution is varied spatially, it is possible to take a bearing by means of the frequency measured in each case. It is also known that it is possible to produce images of layers through the examination subject in this way and by changing the direction of the field gradient.Excitation in one layer of the examination subject is produced in this connection by influencing the magnetic base field by means of a further field gradient so that atomic nuclei are activated in this layer only. This is possible because the excitation is produced with only one frequency, which is associated strictly with the magnetic field in the required layer.
According to the present invention, there is provided equipment for producing an image of at least part of examination subject by means of nuclear magnetic resonance, in which equipment there are means for the application of magnetic fields on to the examination subject and for detecting excursions of atomic nuclei of the examination subject from their state of equilibrium by a high-frequency magnetic excitation pulse, and control means for controlling the image production such that the image produced represents a projection of at least part of the examination subject to be depicted or of parts of the examination subject on to a prescribed plane.
Equipment according to the invention produces a projection not, as in the prior art, which is representation of a selected layer of the examination subject, but instead an image produced which corresponds, for example, to an
X-ray shadow image.
The present invention will now be described, by way of example, with reference to the accompanying drawings, in which:
Figure 1 is a representation of an example of equipment according to the invention;
Figures 2 and 3 are representations to illustrate the operation of the equipment; and
Figure 4 shows details of the equipment according to Figure 1.
Figure 1 shows a patient 2, images of whom are to be produced with the aid of nuclear magnetic resonance, lying on a couch 1. In this connection, there is a coil system 3 having a coil 4 for producing a uniform magnetic field, gradient coils 5 for varying this magnetic field, and an excitation and measuring coil 7. The coil 4 is connected to a power supply 9, and the excitation and measuring coil 7 are connected to a preamplifier 10 and, by means of suitable coupling elements, to a transmitter amplifier 11. The preamplifier 10 supplies a measurement signal via a phase-selective rectifier 1 2 to a process computer 13 which controls the entire measuring procedure.
A high frequency oscillator 14, which may be connected, as shown, via a modulator 1 5 to the transmitter amplifier 11, is used to produce excitation pulses. the images produced are reproduced on a monitor 1 6.
To produce an image of the patient 2 with the aid of nuclear magnetic resonance, the couch 1 is introduced with the aid of a control device 17, which is also controlled by the process computer 13, into the coil system 3 so that a first transverse layer through the patient 2, in whose head several layers are to be imaged, is located such that, as a result of the magnetic field there, nuclear magnetic resonance is excited by an excitation pulse in the coil 7. Data is accumulated from the measurement signal picked up with the aid of the coil 7, which data embodies information relating to a one-dimensional projection of the excited layer through the patient 2 on to a prescribed plane of projection.After this data has been gathered, the couch 1 is displaced longitudinally so that an adjacent, parallel layer through the patient 2 is now positioned at a point at which it can be excited by an excitation pulse of the coil 7.
Data is now accumulated which embodies information relating a one-dimensional projection of this excited layer on to the plane of projection.
Another longitudinal movement is then effected to excite a further parallel layer and data corresponding to this is accumulated, and so on.
There may thus be produced images of a plurality of parallel layers through the patient 2 by means of longitudinally moving the patient 2 on the couch 1, nuclear magnetic resonance being excited in one layer only at a time
The image producing process is completed after all the required parallel layers corresponding to the area to be represented have been excited in this way, and after the processing of the data thereby produced corresponding to the region of the patient 2 to be represented, a projection of which is to be made on to a prescribed plane, more particularly on to the couch 1. An image representing the projection has now been produced.
Instead of the described step-wise longitudinal displacement of the couch 1 with the patient 2, it is also possible to produce the desired images by a step-wise variation of the frequency of the excitation pulse supplied to the coil 7. If the remaining coils have a constant field, the layer in which the atomic nuclei are deflected from their state of equilibrium is caused to move through the patient 2 because the layer in which the excitation takes place in each case depends on the magnetic field and on the frequency of the excitation pulse.
Therefore, in this way it is possible, without moving the patient, to produce data which embodies information relating to a onedimensional projection of the layer excited in each case on to the plane of projection, each of a plurality of parallel layers through the patient 2 being excited, one at a time. The frequency of the excitation pulse can be altered by varying the low frequency supplying the modulator 1 5.
It is also possible to design the equipment so that two-dimensional images of the subject to be depicted can be produced in a known manner and it is therefore possible not to define the layers of which these images are produced. In this case the images represent a parallel projection of the patient 2 on to a prescribed plane. It is also conceivable to project parts only of the patient 2 in this way and to put together several part images to form a larger projection image.
Figure 2 shows that the layer through the patient 2 which is excited is determined by the local variation of the flux intensity and thus the nuclear resonance frequency. The field gradient is represented diagrammatically in Figure 2 and designated by 17. The resonance frequency is designated by f. In this connection the atomic nuclei are excited only in the region of the patient 2 which has been represented.
Figure 3 shows a cross-section through the excited region of the patient 2 and, below that, the pattern of the signal amplitude of the signal measured after the excitation, as a function of the nuclear resonance frequency. As a result of the diagrammatically represented field gradient 1 8 used in this Figure, the signal amplitude is dependent on the nuclear resonance frequency such that a pattern is produced representing a projection of the examined layer of the patient 2 into the direction of the field gradient 1 8. An overall image can now be reconstructed, as described, from several projections of this kind.
Figure 4 represents in more detail one possible construction of the coil system 3. In particular,
Figure 4 shows that the coil 4 is divided into four to produce a uniform magnetic field (base field). It is supplied by the power supply 8. The gradient coils, designated by 5 in Figure 1, are subdivided in the example represented in Figure 4 into two pairs of gradient coils 5a to produce a field gradient in the x-direction, i.e. transverse the couch 1, and into a pair of gradient coils 5b to produce a field gradient in the longitudinal direction of the couch 1 (the z-direction). In the embodiment according to Figure 4, a pair of coils 1 9 connected to a combined high frequency transmitter and receiver system 20 is used to excite atomic nuclei and for the measurement.The process computer 1 3 supplies a drive 21 for the pairs of gradient coils 5a and a drive 22 for the pair of gradient coils 5b. According to Figure 1 it effects the reproduction of the calculated image on the monitor 1 6.
In the example in Figure 4, the couch 1 for the patient 2 consists of a transporting belt passed over rollers 23 and driven in a step-wise manner by a gear mechanism 24 of a stepping motor 25.
The stepping motor 25 is controlled by the process computer 1 3 so that it moves the patient 2 in steps through the coil system 3.
In order to produce two-dimensional images of the subject when the layer is not limited, a ygradient coil system, which corresponds entirely to the gradient coil system 5a rotated by 900 about the magnetic axis, may be provided in addition to the gradient coils represented in Figure 4.
Claims (6)
1. Equipment for producing an image of at least part of examination subject by means of nuclear magnetic resonance, in which equipment there are means for the application of magnetic fields on to the examination subject and for detecting excursions of atomic nuclei of the examination subject from their state of equilibrium by a highfrequency magnetic excitation pulse, and control means for controlling the image production such that the image produced represents a projection of at least part of the examination subject to be depicted or of parts of the examination subject on to a prescribed plane.
2. Equipment according to claim 1 wherein, for the line-by-line formation of the projection, the said means for the application of magnetic fields comprises coils for the selective excitation of nuclear magnetic resonance in a layer perpendicular to the projection direction, from which data is produced which embodies information relating to a one-dimensional projection of the excited layer on to the plane of projection, and wherein a plurality of parallel layers in the examination subject may be excited one at a time by means of the control means.
3. Equipment according to claim 2, wherein, for the excitation of a plurality of parallel layers through the subject, there is a longitudinally displaceable couch for the subject, by means of which the subject may be moved through the coil system.
4. Equipment according to claim 2, wherein the frequency of the excitation pulse can be altered for the excitation of a plurality of parallel layers through the subject.
5. Equipment according to any preceding claim, wherein means is provided for producing twodimensional images of the subject and there is no definition of the layer, of which the images are produced, in the direction of the layer thickness.
6. Equipment for producing an image of at least part of an examination subject by means of nuclear magnetic resonance, substantially as herein described with reference to Figure 1 or
Figures 1 and 4 of the accompanying drawings.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19813124435 DE3124435A1 (en) | 1981-06-22 | 1981-06-22 | DEVICE FOR GENERATING IMAGES OF AN EXAMINATION OBJECT |
Publications (1)
Publication Number | Publication Date |
---|---|
GB2101327A true GB2101327A (en) | 1983-01-12 |
Family
ID=6135087
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB08134194A Withdrawn GB2101327A (en) | 1981-06-22 | 1981-11-12 | Equipment for producing an nmr image as a planar projection |
Country Status (2)
Country | Link |
---|---|
DE (1) | DE3124435A1 (en) |
GB (1) | GB2101327A (en) |
Cited By (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0112663A2 (en) * | 1982-12-17 | 1984-07-04 | Picker International Limited | Nuclear magnetic resonance methods and apparatus |
EP0117134A2 (en) * | 1983-02-16 | 1984-08-29 | Albert Macovski | Improved blood vessel projection imaging system using nuclear magnetic resonance |
EP0136644A2 (en) * | 1983-10-05 | 1985-04-10 | Siemens Aktiengesellschaft | Apparatus for producing images of an object under examination with nuclear magnetic resonance |
EP0150938A2 (en) * | 1984-01-20 | 1985-08-07 | Picker International Limited | Nuclear magnetic resonance apparatus |
EP0164142A1 (en) * | 1984-05-02 | 1985-12-11 | Koninklijke Philips Electronics N.V. | Method of and device for determining a nuclear magnetization distribution in a region of a body |
US4608991A (en) * | 1984-09-26 | 1986-09-02 | Southwest Research Institute | Method for in-vivo NMR measurements in the human breast to screen for small breast cancer in an otherwise healthy breast |
DE3639140A1 (en) * | 1985-11-18 | 1987-05-21 | Toshiba Kawasaki Kk | MAGNETIC RESONANCE SYSTEM |
EP0430322A2 (en) * | 1989-11-18 | 1991-06-05 | Philips Patentverwaltung GmbH | Nuclear spin tomography method and nuclear spin tomograph for carrying out the method |
WO1992006386A1 (en) * | 1990-10-09 | 1992-04-16 | Sri International | Method and apparatus for obtaining in-vivo nmr data from a moving subject |
DE4204294A1 (en) * | 1991-02-15 | 1992-08-20 | Toshiba Kawasaki Kk | METHOD AND DEVICE FOR MEASURING GAPS BETWEEN NEXT FUEL RODS OF A FUEL CASSETTE |
EP0642031A1 (en) * | 1993-09-04 | 1995-03-08 | Philips Patentverwaltung GmbH | Magnetic resonance imaging method and device for carrying out the method |
EP0654675A1 (en) * | 1993-11-22 | 1995-05-24 | Picker International, Inc. | Magnetic resonance apparatus and methods |
EP0710363A4 (en) * | 1993-05-21 | 1996-02-22 | Univ Queensland | Nmr sample holder |
GB2345139A (en) * | 1998-12-24 | 2000-06-28 | Marconi Electronic Syst Ltd | MRI apparatus with continuous movement of patient |
EP1156343A1 (en) * | 2000-04-17 | 2001-11-21 | Esaote S.p.A. | Method and apparatus for nuclear magnetic resonance imaging |
WO2003027701A1 (en) * | 2001-09-25 | 2003-04-03 | Wisconsin Alumni Research Foundation | Magnetic resonance angiography using floating table projection imaging |
WO2004027443A1 (en) * | 2002-09-18 | 2004-04-01 | Koninklijke Philips Electronics N.V. | A method of cyclic magnetic resonance imaging |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3336254A1 (en) * | 1983-10-05 | 1985-04-25 | Siemens AG, 1000 Berlin und 8000 München | DEVICE FOR GENERATING IMAGES OF AN EXAMINATION OBJECT |
-
1981
- 1981-06-22 DE DE19813124435 patent/DE3124435A1/en not_active Withdrawn
- 1981-11-12 GB GB08134194A patent/GB2101327A/en not_active Withdrawn
Cited By (30)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0112663A3 (en) * | 1982-12-17 | 1985-07-03 | Picker International Limited | Nuclear magnetic resonance methods and apparatus |
EP0112663A2 (en) * | 1982-12-17 | 1984-07-04 | Picker International Limited | Nuclear magnetic resonance methods and apparatus |
EP0117134A2 (en) * | 1983-02-16 | 1984-08-29 | Albert Macovski | Improved blood vessel projection imaging system using nuclear magnetic resonance |
EP0117134A3 (en) * | 1983-02-16 | 1986-03-26 | Albert Macovski | Improved blood vessel projection imaging system using nuclear magnetic resonance |
EP0136644A2 (en) * | 1983-10-05 | 1985-04-10 | Siemens Aktiengesellschaft | Apparatus for producing images of an object under examination with nuclear magnetic resonance |
EP0136644A3 (en) * | 1983-10-05 | 1985-06-19 | Siemens Aktiengesellschaft | Apparatus for producing images of an object under examination with nuclear magnetic resonance |
US4644275A (en) * | 1984-01-20 | 1987-02-17 | Picker International Limited | Nuclear magnetic resonance apparatus |
EP0150938A2 (en) * | 1984-01-20 | 1985-08-07 | Picker International Limited | Nuclear magnetic resonance apparatus |
EP0150938A3 (en) * | 1984-01-20 | 1986-05-28 | Picker International Limited | Nuclear magnetic resonance apparatus |
EP0164142A1 (en) * | 1984-05-02 | 1985-12-11 | Koninklijke Philips Electronics N.V. | Method of and device for determining a nuclear magnetization distribution in a region of a body |
US4608991A (en) * | 1984-09-26 | 1986-09-02 | Southwest Research Institute | Method for in-vivo NMR measurements in the human breast to screen for small breast cancer in an otherwise healthy breast |
DE3639140A1 (en) * | 1985-11-18 | 1987-05-21 | Toshiba Kawasaki Kk | MAGNETIC RESONANCE SYSTEM |
US4875485A (en) * | 1985-11-18 | 1989-10-24 | Kabushiki Kaisha Toshiba | Magnetic resonance system |
EP0430322A3 (en) * | 1989-11-18 | 1991-10-09 | Philips Patentverwaltung Gmbh | Nuclear spin tomography method and nuclear spin tomograph for carrying out the method |
US5111144A (en) * | 1989-11-18 | 1992-05-05 | U.S. Philips Corp. | Magnetic resonance tomography method and magnetic resonance tomography apparatus for performing the method |
EP0430322A2 (en) * | 1989-11-18 | 1991-06-05 | Philips Patentverwaltung GmbH | Nuclear spin tomography method and nuclear spin tomograph for carrying out the method |
WO1992006386A1 (en) * | 1990-10-09 | 1992-04-16 | Sri International | Method and apparatus for obtaining in-vivo nmr data from a moving subject |
DE4204294B4 (en) * | 1991-02-15 | 2004-05-13 | Kabushiki Kaisha Toshiba, Kawasaki | Device and method for measuring gaps between adjacent fuel rods of a fuel assembly |
DE4204294A1 (en) * | 1991-02-15 | 1992-08-20 | Toshiba Kawasaki Kk | METHOD AND DEVICE FOR MEASURING GAPS BETWEEN NEXT FUEL RODS OF A FUEL CASSETTE |
EP0710363A4 (en) * | 1993-05-21 | 1996-02-22 | Univ Queensland | Nmr sample holder |
EP0710363A1 (en) * | 1993-05-21 | 1996-05-08 | University Of Queensland | Nmr sample holder |
EP0642031A1 (en) * | 1993-09-04 | 1995-03-08 | Philips Patentverwaltung GmbH | Magnetic resonance imaging method and device for carrying out the method |
EP0654675A1 (en) * | 1993-11-22 | 1995-05-24 | Picker International, Inc. | Magnetic resonance apparatus and methods |
GB2345139A (en) * | 1998-12-24 | 2000-06-28 | Marconi Electronic Syst Ltd | MRI apparatus with continuous movement of patient |
US6385478B1 (en) | 1998-12-24 | 2002-05-07 | Picker International, Inc. | Magnetic resonance imaging apparatus |
EP1156343A1 (en) * | 2000-04-17 | 2001-11-21 | Esaote S.p.A. | Method and apparatus for nuclear magnetic resonance imaging |
WO2003027701A1 (en) * | 2001-09-25 | 2003-04-03 | Wisconsin Alumni Research Foundation | Magnetic resonance angiography using floating table projection imaging |
US6671536B2 (en) | 2001-09-25 | 2003-12-30 | Wisconsin Alumni Research Foundation | Magnetic resonance angiography using floating table projection imaging |
WO2004027443A1 (en) * | 2002-09-18 | 2004-04-01 | Koninklijke Philips Electronics N.V. | A method of cyclic magnetic resonance imaging |
US7496396B2 (en) | 2002-09-18 | 2009-02-24 | Koninklijke Philips Electronics N. V. | Method of cyclic magnetic resonance imaging |
Also Published As
Publication number | Publication date |
---|---|
DE3124435A1 (en) | 1983-01-20 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
WAP | Application withdrawn, taken to be withdrawn or refused ** after publication under section 16(1) |