GB2101327A - Equipment for producing an nmr image as a planar projection - Google Patents

Equipment for producing an nmr image as a planar projection Download PDF

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Publication number
GB2101327A
GB2101327A GB08134194A GB8134194A GB2101327A GB 2101327 A GB2101327 A GB 2101327A GB 08134194 A GB08134194 A GB 08134194A GB 8134194 A GB8134194 A GB 8134194A GB 2101327 A GB2101327 A GB 2101327A
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United Kingdom
Prior art keywords
subject
projection
image
equipment
examination subject
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
GB08134194A
Inventor
Rudolf Shittenhelm
Wilfred Loeffler
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Siemens AG
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Siemens AG
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Publication date
Application filed by Siemens AG filed Critical Siemens AG
Publication of GB2101327A publication Critical patent/GB2101327A/en
Withdrawn legal-status Critical Current

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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01RMEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00Arrangements or instruments for measuring magnetic variables
    • G01R33/20Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/44Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
    • G01R33/48NMR imaging systems
    • G01R33/483NMR imaging systems with selection of signals or spectra from particular regions of the volume, e.g. in vivo spectroscopy
    • G01R33/4833NMR imaging systems with selection of signals or spectra from particular regions of the volume, e.g. in vivo spectroscopy using spatially selective excitation of the volume of interest, e.g. selecting non-orthogonal or inclined slices
    • G01R33/4835NMR imaging systems with selection of signals or spectra from particular regions of the volume, e.g. in vivo spectroscopy using spatially selective excitation of the volume of interest, e.g. selecting non-orthogonal or inclined slices of multiple slices
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01RMEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00Arrangements or instruments for measuring magnetic variables
    • G01R33/20Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/28Details of apparatus provided for in groups G01R33/44 - G01R33/64

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  • Physics & Mathematics (AREA)
  • Condensed Matter Physics & Semiconductors (AREA)
  • General Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • High Energy & Nuclear Physics (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)

Abstract

In a system for imaging a subject 2 by means of nuclear magnetic resonance, and including means 3 for the application of magnetic fields to the subject and for detecting excursions of atomic nuclei of the subject from their state of equilibrium by a high-frequency magnetic excitation pulse, means 13, 17 control the image production so that the image produced represents a projection of at least part of the subject on to a prescribed plane 1. In this way complete pictures, corresponding to X-ray shadow images, are produced with the aid of nuclear magnetic resonance. As described, a magnetic field gradient defines a slice of the subject for projection, successive slices being selected by moving the subject or varying the frequency of the excitation pulse to build up the projection a line at a time. <IMAGE>

Description

SPECIFICATION Equipment for producing an image of at least part of an examination subject The present invention relates to equipment for producing an image of at least part of an examination subject by means of nuclear magnetic resonance. More particularly, the present invention relates to such equipment in which there are means for the application of magnetic fields on to the examination subject and for detecting the excursions of atomic nuclei of the examination subject from their state of equilibriun of a high-frequency magnetic excitation pulse.
It is known that hydrogen atomic nuclei, in particuiar, of an examination subject can be deflected from a preferred direction, which is produced by magnetic base field, by a highfrequency excitation pulse and that, when the excitation pulse ceases, there is a certain delay before the atomic nuclei level off into the preferred direction, as a result of their spin. During this delay, the atomic nuclei precess with a frequency determined by the strength of the magnetic base field. If a field gradient is superimposed on this uniform magnetic base field so that the magnetic field distribution is varied spatially, it is possible to take a bearing by means of the frequency measured in each case. It is also known that it is possible to produce images of layers through the examination subject in this way and by changing the direction of the field gradient.Excitation in one layer of the examination subject is produced in this connection by influencing the magnetic base field by means of a further field gradient so that atomic nuclei are activated in this layer only. This is possible because the excitation is produced with only one frequency, which is associated strictly with the magnetic field in the required layer.
According to the present invention, there is provided equipment for producing an image of at least part of examination subject by means of nuclear magnetic resonance, in which equipment there are means for the application of magnetic fields on to the examination subject and for detecting excursions of atomic nuclei of the examination subject from their state of equilibrium by a high-frequency magnetic excitation pulse, and control means for controlling the image production such that the image produced represents a projection of at least part of the examination subject to be depicted or of parts of the examination subject on to a prescribed plane.
Equipment according to the invention produces a projection not, as in the prior art, which is representation of a selected layer of the examination subject, but instead an image produced which corresponds, for example, to an X-ray shadow image.
The present invention will now be described, by way of example, with reference to the accompanying drawings, in which: Figure 1 is a representation of an example of equipment according to the invention; Figures 2 and 3 are representations to illustrate the operation of the equipment; and Figure 4 shows details of the equipment according to Figure 1.
Figure 1 shows a patient 2, images of whom are to be produced with the aid of nuclear magnetic resonance, lying on a couch 1. In this connection, there is a coil system 3 having a coil 4 for producing a uniform magnetic field, gradient coils 5 for varying this magnetic field, and an excitation and measuring coil 7. The coil 4 is connected to a power supply 9, and the excitation and measuring coil 7 are connected to a preamplifier 10 and, by means of suitable coupling elements, to a transmitter amplifier 11. The preamplifier 10 supplies a measurement signal via a phase-selective rectifier 1 2 to a process computer 13 which controls the entire measuring procedure.
A high frequency oscillator 14, which may be connected, as shown, via a modulator 1 5 to the transmitter amplifier 11, is used to produce excitation pulses. the images produced are reproduced on a monitor 1 6.
To produce an image of the patient 2 with the aid of nuclear magnetic resonance, the couch 1 is introduced with the aid of a control device 17, which is also controlled by the process computer 13, into the coil system 3 so that a first transverse layer through the patient 2, in whose head several layers are to be imaged, is located such that, as a result of the magnetic field there, nuclear magnetic resonance is excited by an excitation pulse in the coil 7. Data is accumulated from the measurement signal picked up with the aid of the coil 7, which data embodies information relating to a one-dimensional projection of the excited layer through the patient 2 on to a prescribed plane of projection.After this data has been gathered, the couch 1 is displaced longitudinally so that an adjacent, parallel layer through the patient 2 is now positioned at a point at which it can be excited by an excitation pulse of the coil 7.
Data is now accumulated which embodies information relating a one-dimensional projection of this excited layer on to the plane of projection.
Another longitudinal movement is then effected to excite a further parallel layer and data corresponding to this is accumulated, and so on.
There may thus be produced images of a plurality of parallel layers through the patient 2 by means of longitudinally moving the patient 2 on the couch 1, nuclear magnetic resonance being excited in one layer only at a time The image producing process is completed after all the required parallel layers corresponding to the area to be represented have been excited in this way, and after the processing of the data thereby produced corresponding to the region of the patient 2 to be represented, a projection of which is to be made on to a prescribed plane, more particularly on to the couch 1. An image representing the projection has now been produced.
Instead of the described step-wise longitudinal displacement of the couch 1 with the patient 2, it is also possible to produce the desired images by a step-wise variation of the frequency of the excitation pulse supplied to the coil 7. If the remaining coils have a constant field, the layer in which the atomic nuclei are deflected from their state of equilibrium is caused to move through the patient 2 because the layer in which the excitation takes place in each case depends on the magnetic field and on the frequency of the excitation pulse.
Therefore, in this way it is possible, without moving the patient, to produce data which embodies information relating to a onedimensional projection of the layer excited in each case on to the plane of projection, each of a plurality of parallel layers through the patient 2 being excited, one at a time. The frequency of the excitation pulse can be altered by varying the low frequency supplying the modulator 1 5.
It is also possible to design the equipment so that two-dimensional images of the subject to be depicted can be produced in a known manner and it is therefore possible not to define the layers of which these images are produced. In this case the images represent a parallel projection of the patient 2 on to a prescribed plane. It is also conceivable to project parts only of the patient 2 in this way and to put together several part images to form a larger projection image.
Figure 2 shows that the layer through the patient 2 which is excited is determined by the local variation of the flux intensity and thus the nuclear resonance frequency. The field gradient is represented diagrammatically in Figure 2 and designated by 17. The resonance frequency is designated by f. In this connection the atomic nuclei are excited only in the region of the patient 2 which has been represented.
Figure 3 shows a cross-section through the excited region of the patient 2 and, below that, the pattern of the signal amplitude of the signal measured after the excitation, as a function of the nuclear resonance frequency. As a result of the diagrammatically represented field gradient 1 8 used in this Figure, the signal amplitude is dependent on the nuclear resonance frequency such that a pattern is produced representing a projection of the examined layer of the patient 2 into the direction of the field gradient 1 8. An overall image can now be reconstructed, as described, from several projections of this kind.
Figure 4 represents in more detail one possible construction of the coil system 3. In particular, Figure 4 shows that the coil 4 is divided into four to produce a uniform magnetic field (base field). It is supplied by the power supply 8. The gradient coils, designated by 5 in Figure 1, are subdivided in the example represented in Figure 4 into two pairs of gradient coils 5a to produce a field gradient in the x-direction, i.e. transverse the couch 1, and into a pair of gradient coils 5b to produce a field gradient in the longitudinal direction of the couch 1 (the z-direction). In the embodiment according to Figure 4, a pair of coils 1 9 connected to a combined high frequency transmitter and receiver system 20 is used to excite atomic nuclei and for the measurement.The process computer 1 3 supplies a drive 21 for the pairs of gradient coils 5a and a drive 22 for the pair of gradient coils 5b. According to Figure 1 it effects the reproduction of the calculated image on the monitor 1 6.
In the example in Figure 4, the couch 1 for the patient 2 consists of a transporting belt passed over rollers 23 and driven in a step-wise manner by a gear mechanism 24 of a stepping motor 25.
The stepping motor 25 is controlled by the process computer 1 3 so that it moves the patient 2 in steps through the coil system 3.
In order to produce two-dimensional images of the subject when the layer is not limited, a ygradient coil system, which corresponds entirely to the gradient coil system 5a rotated by 900 about the magnetic axis, may be provided in addition to the gradient coils represented in Figure 4.

Claims (6)

1. Equipment for producing an image of at least part of examination subject by means of nuclear magnetic resonance, in which equipment there are means for the application of magnetic fields on to the examination subject and for detecting excursions of atomic nuclei of the examination subject from their state of equilibrium by a highfrequency magnetic excitation pulse, and control means for controlling the image production such that the image produced represents a projection of at least part of the examination subject to be depicted or of parts of the examination subject on to a prescribed plane.
2. Equipment according to claim 1 wherein, for the line-by-line formation of the projection, the said means for the application of magnetic fields comprises coils for the selective excitation of nuclear magnetic resonance in a layer perpendicular to the projection direction, from which data is produced which embodies information relating to a one-dimensional projection of the excited layer on to the plane of projection, and wherein a plurality of parallel layers in the examination subject may be excited one at a time by means of the control means.
3. Equipment according to claim 2, wherein, for the excitation of a plurality of parallel layers through the subject, there is a longitudinally displaceable couch for the subject, by means of which the subject may be moved through the coil system.
4. Equipment according to claim 2, wherein the frequency of the excitation pulse can be altered for the excitation of a plurality of parallel layers through the subject.
5. Equipment according to any preceding claim, wherein means is provided for producing twodimensional images of the subject and there is no definition of the layer, of which the images are produced, in the direction of the layer thickness.
6. Equipment for producing an image of at least part of an examination subject by means of nuclear magnetic resonance, substantially as herein described with reference to Figure 1 or Figures 1 and 4 of the accompanying drawings.
GB08134194A 1981-06-22 1981-11-12 Equipment for producing an nmr image as a planar projection Withdrawn GB2101327A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19813124435 DE3124435A1 (en) 1981-06-22 1981-06-22 DEVICE FOR GENERATING IMAGES OF AN EXAMINATION OBJECT

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Cited By (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0112663A2 (en) * 1982-12-17 1984-07-04 Picker International Limited Nuclear magnetic resonance methods and apparatus
EP0117134A2 (en) * 1983-02-16 1984-08-29 Albert Macovski Improved blood vessel projection imaging system using nuclear magnetic resonance
EP0136644A2 (en) * 1983-10-05 1985-04-10 Siemens Aktiengesellschaft Apparatus for producing images of an object under examination with nuclear magnetic resonance
EP0150938A2 (en) * 1984-01-20 1985-08-07 Picker International Limited Nuclear magnetic resonance apparatus
EP0164142A1 (en) * 1984-05-02 1985-12-11 Koninklijke Philips Electronics N.V. Method of and device for determining a nuclear magnetization distribution in a region of a body
US4608991A (en) * 1984-09-26 1986-09-02 Southwest Research Institute Method for in-vivo NMR measurements in the human breast to screen for small breast cancer in an otherwise healthy breast
DE3639140A1 (en) * 1985-11-18 1987-05-21 Toshiba Kawasaki Kk MAGNETIC RESONANCE SYSTEM
EP0430322A2 (en) * 1989-11-18 1991-06-05 Philips Patentverwaltung GmbH Nuclear spin tomography method and nuclear spin tomograph for carrying out the method
WO1992006386A1 (en) * 1990-10-09 1992-04-16 Sri International Method and apparatus for obtaining in-vivo nmr data from a moving subject
DE4204294A1 (en) * 1991-02-15 1992-08-20 Toshiba Kawasaki Kk METHOD AND DEVICE FOR MEASURING GAPS BETWEEN NEXT FUEL RODS OF A FUEL CASSETTE
EP0642031A1 (en) * 1993-09-04 1995-03-08 Philips Patentverwaltung GmbH Magnetic resonance imaging method and device for carrying out the method
EP0654675A1 (en) * 1993-11-22 1995-05-24 Picker International, Inc. Magnetic resonance apparatus and methods
EP0710363A4 (en) * 1993-05-21 1996-02-22 Univ Queensland Nmr sample holder
GB2345139A (en) * 1998-12-24 2000-06-28 Marconi Electronic Syst Ltd MRI apparatus with continuous movement of patient
EP1156343A1 (en) * 2000-04-17 2001-11-21 Esaote S.p.A. Method and apparatus for nuclear magnetic resonance imaging
WO2003027701A1 (en) * 2001-09-25 2003-04-03 Wisconsin Alumni Research Foundation Magnetic resonance angiography using floating table projection imaging
WO2004027443A1 (en) * 2002-09-18 2004-04-01 Koninklijke Philips Electronics N.V. A method of cyclic magnetic resonance imaging

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3336254A1 (en) * 1983-10-05 1985-04-25 Siemens AG, 1000 Berlin und 8000 München DEVICE FOR GENERATING IMAGES OF AN EXAMINATION OBJECT

Cited By (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0112663A3 (en) * 1982-12-17 1985-07-03 Picker International Limited Nuclear magnetic resonance methods and apparatus
EP0112663A2 (en) * 1982-12-17 1984-07-04 Picker International Limited Nuclear magnetic resonance methods and apparatus
EP0117134A2 (en) * 1983-02-16 1984-08-29 Albert Macovski Improved blood vessel projection imaging system using nuclear magnetic resonance
EP0117134A3 (en) * 1983-02-16 1986-03-26 Albert Macovski Improved blood vessel projection imaging system using nuclear magnetic resonance
EP0136644A2 (en) * 1983-10-05 1985-04-10 Siemens Aktiengesellschaft Apparatus for producing images of an object under examination with nuclear magnetic resonance
EP0136644A3 (en) * 1983-10-05 1985-06-19 Siemens Aktiengesellschaft Apparatus for producing images of an object under examination with nuclear magnetic resonance
US4644275A (en) * 1984-01-20 1987-02-17 Picker International Limited Nuclear magnetic resonance apparatus
EP0150938A2 (en) * 1984-01-20 1985-08-07 Picker International Limited Nuclear magnetic resonance apparatus
EP0150938A3 (en) * 1984-01-20 1986-05-28 Picker International Limited Nuclear magnetic resonance apparatus
EP0164142A1 (en) * 1984-05-02 1985-12-11 Koninklijke Philips Electronics N.V. Method of and device for determining a nuclear magnetization distribution in a region of a body
US4608991A (en) * 1984-09-26 1986-09-02 Southwest Research Institute Method for in-vivo NMR measurements in the human breast to screen for small breast cancer in an otherwise healthy breast
DE3639140A1 (en) * 1985-11-18 1987-05-21 Toshiba Kawasaki Kk MAGNETIC RESONANCE SYSTEM
US4875485A (en) * 1985-11-18 1989-10-24 Kabushiki Kaisha Toshiba Magnetic resonance system
EP0430322A3 (en) * 1989-11-18 1991-10-09 Philips Patentverwaltung Gmbh Nuclear spin tomography method and nuclear spin tomograph for carrying out the method
US5111144A (en) * 1989-11-18 1992-05-05 U.S. Philips Corp. Magnetic resonance tomography method and magnetic resonance tomography apparatus for performing the method
EP0430322A2 (en) * 1989-11-18 1991-06-05 Philips Patentverwaltung GmbH Nuclear spin tomography method and nuclear spin tomograph for carrying out the method
WO1992006386A1 (en) * 1990-10-09 1992-04-16 Sri International Method and apparatus for obtaining in-vivo nmr data from a moving subject
DE4204294B4 (en) * 1991-02-15 2004-05-13 Kabushiki Kaisha Toshiba, Kawasaki Device and method for measuring gaps between adjacent fuel rods of a fuel assembly
DE4204294A1 (en) * 1991-02-15 1992-08-20 Toshiba Kawasaki Kk METHOD AND DEVICE FOR MEASURING GAPS BETWEEN NEXT FUEL RODS OF A FUEL CASSETTE
EP0710363A4 (en) * 1993-05-21 1996-02-22 Univ Queensland Nmr sample holder
EP0710363A1 (en) * 1993-05-21 1996-05-08 University Of Queensland Nmr sample holder
EP0642031A1 (en) * 1993-09-04 1995-03-08 Philips Patentverwaltung GmbH Magnetic resonance imaging method and device for carrying out the method
EP0654675A1 (en) * 1993-11-22 1995-05-24 Picker International, Inc. Magnetic resonance apparatus and methods
GB2345139A (en) * 1998-12-24 2000-06-28 Marconi Electronic Syst Ltd MRI apparatus with continuous movement of patient
US6385478B1 (en) 1998-12-24 2002-05-07 Picker International, Inc. Magnetic resonance imaging apparatus
EP1156343A1 (en) * 2000-04-17 2001-11-21 Esaote S.p.A. Method and apparatus for nuclear magnetic resonance imaging
WO2003027701A1 (en) * 2001-09-25 2003-04-03 Wisconsin Alumni Research Foundation Magnetic resonance angiography using floating table projection imaging
US6671536B2 (en) 2001-09-25 2003-12-30 Wisconsin Alumni Research Foundation Magnetic resonance angiography using floating table projection imaging
WO2004027443A1 (en) * 2002-09-18 2004-04-01 Koninklijke Philips Electronics N.V. A method of cyclic magnetic resonance imaging
US7496396B2 (en) 2002-09-18 2009-02-24 Koninklijke Philips Electronics N. V. Method of cyclic magnetic resonance imaging

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