GB2077132A - Filtration device for concentration of liquid media - Google Patents
Filtration device for concentration of liquid media Download PDFInfo
- Publication number
- GB2077132A GB2077132A GB8114791A GB8114791A GB2077132A GB 2077132 A GB2077132 A GB 2077132A GB 8114791 A GB8114791 A GB 8114791A GB 8114791 A GB8114791 A GB 8114791A GB 2077132 A GB2077132 A GB 2077132A
- Authority
- GB
- United Kingdom
- Prior art keywords
- housing
- chamber
- concentrate
- filtrate
- diaphragm
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 238000001914 filtration Methods 0.000 title claims abstract description 23
- 239000007788 liquid Substances 0.000 title claims abstract description 18
- 239000012141 concentrate Substances 0.000 claims abstract description 28
- 239000000706 filtrate Substances 0.000 claims abstract description 28
- 230000000717 retained effect Effects 0.000 claims 1
- 239000012780 transparent material Substances 0.000 claims 1
- 210000000188 diaphragm Anatomy 0.000 description 12
- 238000004049 embossing Methods 0.000 description 3
- 239000000463 material Substances 0.000 description 3
- 239000000523 sample Substances 0.000 description 3
- 230000002745 absorbent Effects 0.000 description 2
- 239000002250 absorbent Substances 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 239000011148 porous material Substances 0.000 description 2
- 238000004026 adhesive bonding Methods 0.000 description 1
- 238000004458 analytical method Methods 0.000 description 1
- 239000012472 biological sample Substances 0.000 description 1
- 238000010276 construction Methods 0.000 description 1
- 230000001419 dependent effect Effects 0.000 description 1
- 230000002209 hydrophobic effect Effects 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 229920003023 plastic Polymers 0.000 description 1
- 238000003466 welding Methods 0.000 description 1
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D29/00—Filters with filtering elements stationary during filtration, e.g. pressure or suction filters, not covered by groups B01D24/00 - B01D27/00; Filtering elements therefor
- B01D29/01—Filters with filtering elements stationary during filtration, e.g. pressure or suction filters, not covered by groups B01D24/00 - B01D27/00; Filtering elements therefor with flat filtering elements
- B01D29/03—Filters with filtering elements stationary during filtration, e.g. pressure or suction filters, not covered by groups B01D24/00 - B01D27/00; Filtering elements therefor with flat filtering elements self-supporting
Landscapes
- Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Sampling And Sample Adjustment (AREA)
- Separation Using Semi-Permeable Membranes (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Abstract
A filtration device for concentration of liquid media comprises a diaphragm means (6, 7) which is arranged and supported in a transparent housing (1, 2), is loaded by the liquid column of the medium and which divides the housing into a concentrate chamber (14) and a filtrate chamber (15), the concentrate chamber (14) ending in an impermeable, funnel-shaped lowermost portion (3) arranged directly opposite to an inlet and outlet opening (5). The diaphragm means (6, 7) divides the housing (1, 2) nearly vertically-diagonally and the filtrate chamber (15), which is arranged underneath the concentrate chamber (14), is provided in its uppermost region (4) with a filtrate outlet (9, 10) connectible to a suction device. The concentrate is removed from the lowermost portion (3) by means of a pipette passed through the opening 5. <IMAGE>
Description
SPECIFICATION
Filtration device for concentration of liquid media
The present invention relates to a filtration device for concentration of liquid media, especially biological samples in which the suspected effective sibstance is not present in such a concentration that optimum conditions are attainable during examination.
In a known filtration device described in
German (Fed. Rep) patent specification No.
23 34 375, a layer which is absorbent and thereby capable of suction is arranged directly behind a porous diaphragm and a further resilient layer of film material is arranged behind this layer. The diaphragm and both layers are arranged vertically. The diaphragm in this vertical arrangement is loaded by the liquid column of the liquid sample introduced into a concentrate chamber. The layer capable of suction ensures that the filtrate, or stated more precisely the greater part of the carrier liquid of the sample, passes through the pores of the diaphragm and into the layer capable of suction. The filtrate as such is thus lost. The concentration process is concluded when the concentrate collects in a funnel-shaped lowermost region which is liquid-tight.The filtration process extends over several hours as this operation is dependent on the suction force of the absorbent layer and naturally also on the kind of liquid to be filtered.
The disadvantage of this device is that the filtration process takes an unduly long period of time. It is often desired in laboratory operation for rapid analyses to obtain the sample to be examined rapidly in the desired concentration. For certain examinations, it as also desired to examine the filtrate itself or to employ the obtained filtrate for other purposes.
There is accordingly a need for a filtration device wherein a rapid filtration and thereby concentration of liquid samples is possible and the filtrate is available for examinations.
According to the present invention there is provided a filtration device for concentration of liquid media, comprising a housing and filtration diaphragm means loadable by such a medium and so supported by and extending substantially diagonally in the housing as to divide the interior space thereof into a filtrate chamber and a concentrate chamber which is disposed above the filtrate chamber and the lowermost portion of which is of substantially funnel-shaped cross-section and bounded by impermeable wall means, the housing being provided with concentrate inlet and outlet means communicating with the concentrate chamber opposite said lowermost portion and with filtrate outlet means communicating with the filtrate chamber in an upper region thereof and connectible to suction means for applying suction to the filtrate chamber.
An embodiment of the present invention will now be more particularly described, by way of example, with reference to the accompanying drawings, in which:~
Figure 1 is a vertical section of a filtration device according to the said embodiment,
Figure 2 is a perspective view of a modified filtration device, and
Figure 3 is a side elevation of a filtration unit comprising a plurality of the filtration devices.
Referring now to the drawings, there is shown a filtration device which comprises a box-shaped housing which consists of a housing part 1, which forms a concentrate chamber 14, and a housing part 2, which forms a filtrate chamber 15. The housing part 2 has an encircling collar 11, which on the one hand forms a support ror a diaphragm support 7 carrying a filter diaphragm element 6 and on the other hand acts as an ultrasonic welding lip or a gluing lip for the rim of the housing part 1.The diaphragm element 6 and the diaphragm support 7 the latter having passage openings G, are arranged nearly verti cally-diagonally in the housing interior space and thereby separate the concentrate chamber 14 Irom the filtrate chamber 15. The dia phragm element 6 has a pore size suitable for the respective filtration process and is impermeable in the region of the lowermost portion 3 of the concentrate chamber 14. This can be achieved in a simple manner by making the region 6' of the diaphragm element 6 hydrophobic. As shown in Fig. 1, the lowermost portion 3 is construczad as constriction which allows. introduction of a needle pipette through an opening 5 in a lid of the housing.
The opening 5 is closable by a tongue closure 16 formed from the material of the housing lid.
In the region of its uppermost portion 4, the filtrate chamber 15 has an outlet 9 for the filtrate and a ventilating nozzle 10, the outlet enabling the filtrate to be poured out.
The housing part 1 has embossings 12, which indicate the degree of filling and also the concentration achieved when the liquid in the concentrate chamber 1 4 has fallen to a particular one of the embossings 12. The liquid level of the concentrate can, however, fall in the concentrate chamber 14 at most only to the lowermost marking 1 2' or up to the beginning of the impermeable filter zone 6'. The outlet 9 is preferably constructed as protruding stub pipe in the shape of a Luer cone and is suitable for the connection of a suction pump.
In the construction shown in Fig. 2, a specially formed lowermost portion of the type shown in Fig. 1 has been dispensed with.
Here, the lowermost portion 3' is arranged so that a needle pipette is guided to the lower: most corner of the concentrate chamber 14 and the Filter 6, 7 in that case assumes a slightly inclined position. The inlet 5' of the concentrate chamber 14 is formed by a stub pipe which is connectible to a pressure medium source in order to be able to accelerate the concentration process.
Several such filter devices can be united as shown in Fig. 3 in a frame 13 to increase their stability.
In operation, liquid to be concentrated is fed through the inlet 5 or 5' into the concentrate chamber 14 up to the uppermost embossing 12. With the aid of a suction pump placed on the outlet stub pipe 9, 10, an underpressure is generated in the filtrate chamber 15 so that the main part of the carrier liquid is sucked out of the concentrate chamber 14 through the diaphragm element 6 and through the openings 8 of the support 7 into the filtrate chamber 15. When the desired degree of concentration has been achieved, the concentrated liquid can be withdrawn from the concentrate chamber 14.
Equally, the filtrate can be removed from the filtrate chamber 15 through the outlet stub pipe 9, 10.
The filter unit is produced from transparent plastics material. Due to the simple shape, manufacture is cheap and is suitable for simple use.
Claims (12)
1. A filtration device for concentration of liquid media, comprising a housing and filtration diaphragm means loadable by such a medium and so supported by and extending substantially diagonally in the housing as to divide the interior space thereof into a filtrate chamber and a concentrate chamber which is disposed above the filtrate chamber and the lowermost portion of which is of substantially funnel-shaped cross-section and bounded by impermeable wall means, the housing being provided with concentrate inlet and outlet means communicating with the concentrate chamber opposite said lowermost portion and with filtrate outlet means communicating with the filtrate chamber in an upper region thereof and connectible to suction means for applying suction to the filtrate chamber.
2. A device as claimed in claim 1, the filtrate outlet means being provided by a stub pipe projecting outwardly of the housing and defining a main flow passage and a ventilating duct.
3. A device as claimed in either claim 1 or claim 2, wherein said lowermost portion of the concentrate chamber includes a constriction for reception of a needle pipette.
4. A device as claimed in any one of the preceding claims, said wall means being provided at least in part by a liquid-tight portion of a diaphragm element of the diaphragm means.
5. A device as claimed in any one of claims 1 to 3, said wall means being provided at least in part by a liquid-tight portion of a diaphragm element support of the diaphragm means.
6. A device as claimed in any one of the preceding claims, wherein the housing comprises two housing parts permanently connected together with the diaphragm means retained therebetween.
7. A device as claimed in any one of the preceding claims, wherein the housing is further provided with a cover element having an openable portion closing the concentrate inlet and outlet means.
8. A device as claimed in any one of the preceding claims, wherein the housing is of transparent material and provided with level indicating means arranged to indicate different filling levels of the concentrate chamber.
9. A device as claimed in any one of the preceding claims, the concentrate inlet and outlet means being provided by a stub pipe connectible to a source of pressure medium pressurisation of the concentrate chamber.
10. A filtration device for concentration of liquid media, the device being substantially as hereinbefore described with reference to Fig.
1 or Fig. 2 of the accompanying drawings.
11. A filtration unit comprising a plurality of filtration devices as claimed in any one of the preceding claims and a common mounting frame mounting the housings of the devices together.
12. A filtration unit as claimed in claim 11 and substantially as hereinbefore described with reference to Fig. 3 of the accompanying drawings.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19803020041 DE3020041A1 (en) | 1980-05-24 | 1980-05-24 | FILTRATION DEVICE FOR CONCENTRATING LIQUID MEDIA |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| GB2077132A true GB2077132A (en) | 1981-12-16 |
| GB2077132B GB2077132B (en) | 1984-01-18 |
Family
ID=6103316
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB8114791A Expired GB2077132B (en) | 1980-05-24 | 1981-05-14 | Filtration device for concentration of liquid media |
Country Status (3)
| Country | Link |
|---|---|
| DE (1) | DE3020041A1 (en) |
| FR (1) | FR2482866A1 (en) |
| GB (1) | GB2077132B (en) |
Cited By (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2154317A (en) * | 1984-01-17 | 1985-09-04 | English Clays Lovering Pochin | Measurement of physical properties of the solid component of a slurry |
| US5861094A (en) * | 1997-04-17 | 1999-01-19 | Goehde; Wolfgang | Filter for biological particle separation |
| US5970782A (en) * | 1997-05-16 | 1999-10-26 | Life Technologies, Inc. | Gradient filtration apparatus |
| US11207497B1 (en) | 2020-08-11 | 2021-12-28 | Imperative Care, Inc. | Catheter with enhanced tensile strength |
| US11253277B2 (en) | 2019-12-18 | 2022-02-22 | Imperative Care, Inc. | Systems for accessing a central pulmonary artery |
| US11259821B2 (en) | 2019-12-18 | 2022-03-01 | Imperative Care, Inc. | Aspiration system with accelerated response |
| US11311303B2 (en) | 2018-05-01 | 2022-04-26 | Incept, Llc | Enhanced flexibility neurovascular catheter with tensile support |
| US11395665B2 (en) | 2018-05-01 | 2022-07-26 | Incept, Llc | Devices and methods for removing obstructive material, from an intravascular site |
| US11471582B2 (en) | 2018-07-06 | 2022-10-18 | Incept, Llc | Vacuum transfer tool for extendable catheter |
| US11504020B2 (en) | 2019-10-15 | 2022-11-22 | Imperative Care, Inc. | Systems and methods for multivariate stroke detection |
| US11517335B2 (en) | 2018-07-06 | 2022-12-06 | Incept, Llc | Sealed neurovascular extendable catheter |
| US11553935B2 (en) | 2019-12-18 | 2023-01-17 | Imperative Care, Inc. | Sterile field clot capture module for use in thrombectomy system |
| US11565082B2 (en) | 2020-03-10 | 2023-01-31 | Imperative Care, Inc. | Enhanced flexibility neurovascular catheter |
| US11903588B2 (en) | 2017-01-06 | 2024-02-20 | Incept, Llc | Thromboresistant coatings for aneurysm treatment devices |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11426683B2 (en) | 2019-04-03 | 2022-08-30 | Gregg Lynn Williams | Negative pressure filtration apparatus, method, and system |
-
1980
- 1980-05-24 DE DE19803020041 patent/DE3020041A1/en not_active Withdrawn
-
1981
- 1981-05-14 GB GB8114791A patent/GB2077132B/en not_active Expired
- 1981-05-22 FR FR8110262A patent/FR2482866A1/en active Granted
Cited By (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2154317A (en) * | 1984-01-17 | 1985-09-04 | English Clays Lovering Pochin | Measurement of physical properties of the solid component of a slurry |
| US4704899A (en) * | 1984-01-17 | 1987-11-10 | English Clays Lovering Pochin & Company, Limited | Measurement of physical properties of the solid component of a slurry |
| US5861094A (en) * | 1997-04-17 | 1999-01-19 | Goehde; Wolfgang | Filter for biological particle separation |
| US5970782A (en) * | 1997-05-16 | 1999-10-26 | Life Technologies, Inc. | Gradient filtration apparatus |
| US11903588B2 (en) | 2017-01-06 | 2024-02-20 | Incept, Llc | Thromboresistant coatings for aneurysm treatment devices |
| US11311303B2 (en) | 2018-05-01 | 2022-04-26 | Incept, Llc | Enhanced flexibility neurovascular catheter with tensile support |
| US11395665B2 (en) | 2018-05-01 | 2022-07-26 | Incept, Llc | Devices and methods for removing obstructive material, from an intravascular site |
| US11517335B2 (en) | 2018-07-06 | 2022-12-06 | Incept, Llc | Sealed neurovascular extendable catheter |
| US11471582B2 (en) | 2018-07-06 | 2022-10-18 | Incept, Llc | Vacuum transfer tool for extendable catheter |
| US11504020B2 (en) | 2019-10-15 | 2022-11-22 | Imperative Care, Inc. | Systems and methods for multivariate stroke detection |
| US11457936B2 (en) | 2019-12-18 | 2022-10-04 | Imperative Care, Inc. | Catheter system for treating thromboembolic disease |
| US11439799B2 (en) | 2019-12-18 | 2022-09-13 | Imperative Care, Inc. | Split dilator aspiration system |
| US11259821B2 (en) | 2019-12-18 | 2022-03-01 | Imperative Care, Inc. | Aspiration system with accelerated response |
| US11253277B2 (en) | 2019-12-18 | 2022-02-22 | Imperative Care, Inc. | Systems for accessing a central pulmonary artery |
| US11553935B2 (en) | 2019-12-18 | 2023-01-17 | Imperative Care, Inc. | Sterile field clot capture module for use in thrombectomy system |
| US11633272B2 (en) | 2019-12-18 | 2023-04-25 | Imperative Care, Inc. | Manually rotatable thrombus engagement tool |
| US11638637B2 (en) | 2019-12-18 | 2023-05-02 | Imperative Care, Inc. | Method of removing embolic material with thrombus engagement tool |
| US11819228B2 (en) | 2019-12-18 | 2023-11-21 | Imperative Care, Inc. | Methods and systems for treating a pulmonary embolism |
| US11565082B2 (en) | 2020-03-10 | 2023-01-31 | Imperative Care, Inc. | Enhanced flexibility neurovascular catheter |
| US11207497B1 (en) | 2020-08-11 | 2021-12-28 | Imperative Care, Inc. | Catheter with enhanced tensile strength |
Also Published As
| Publication number | Publication date |
|---|---|
| GB2077132B (en) | 1984-01-18 |
| FR2482866A1 (en) | 1981-11-27 |
| DE3020041A1 (en) | 1981-12-03 |
| FR2482866B3 (en) | 1983-02-25 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PCNP | Patent ceased through non-payment of renewal fee |