GB2072165B - 1-(2-mercaptocycloalkyl)carbonyl-l-proline derivatives the process for their manufacture the intermediates for their synthesis and their use as antihypertensive agents - Google Patents

1-(2-mercaptocycloalkyl)carbonyl-l-proline derivatives the process for their manufacture the intermediates for their synthesis and their use as antihypertensive agents

Info

Publication number
GB2072165B
GB2072165B GB8104745A GB8104745A GB2072165B GB 2072165 B GB2072165 B GB 2072165B GB 8104745 A GB8104745 A GB 8104745A GB 8104745 A GB8104745 A GB 8104745A GB 2072165 B GB2072165 B GB 2072165B
Authority
GB
United Kingdom
Prior art keywords
mercaptocycloalkyl
intermediates
carbonyl
synthesis
manufacture
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB8104745A
Other versions
GB2072165A (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Gruppo Lepetit SpA
Original Assignee
Gruppo Lepetit SpA
Lepetit SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gruppo Lepetit SpA, Lepetit SpA filed Critical Gruppo Lepetit SpA
Priority to GB8104745A priority Critical patent/GB2072165B/en
Publication of GB2072165A publication Critical patent/GB2072165A/en
Application granted granted Critical
Publication of GB2072165B publication Critical patent/GB2072165B/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C327/00—Thiocarboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C61/00—Compounds having carboxyl groups bound to carbon atoms of rings other than six-membered aromatic rings
    • C07C61/16—Unsaturated compounds
    • C07C61/20—Unsaturated compounds having a carboxyl group bound to a five-membered ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/16—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pyrrole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
GB8104745A 1980-03-07 1981-02-16 1-(2-mercaptocycloalkyl)carbonyl-l-proline derivatives the process for their manufacture the intermediates for their synthesis and their use as antihypertensive agents Expired GB2072165B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
GB8104745A GB2072165B (en) 1980-03-07 1981-02-16 1-(2-mercaptocycloalkyl)carbonyl-l-proline derivatives the process for their manufacture the intermediates for their synthesis and their use as antihypertensive agents

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB8007756 1980-03-07
GB8104745A GB2072165B (en) 1980-03-07 1981-02-16 1-(2-mercaptocycloalkyl)carbonyl-l-proline derivatives the process for their manufacture the intermediates for their synthesis and their use as antihypertensive agents

Publications (2)

Publication Number Publication Date
GB2072165A GB2072165A (en) 1981-09-30
GB2072165B true GB2072165B (en) 1983-11-23

Family

ID=26274728

Family Applications (1)

Application Number Title Priority Date Filing Date
GB8104745A Expired GB2072165B (en) 1980-03-07 1981-02-16 1-(2-mercaptocycloalkyl)carbonyl-l-proline derivatives the process for their manufacture the intermediates for their synthesis and their use as antihypertensive agents

Country Status (1)

Country Link
GB (1) GB2072165B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU542211B2 (en) * 1980-03-07 1985-02-14 Gruppo Lepetit S.P.A. Mercaptocycloalkyl carbonyl prolines
DE3915756A1 (en) * 1989-05-13 1990-11-29 Bayer Ag CYCLOPROPANOYLAMINOSAEUREAMID DERIVATIVES

Also Published As

Publication number Publication date
GB2072165A (en) 1981-09-30

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Legal Events

Date Code Title Description
PCNP Patent ceased through non-payment of renewal fee

Effective date: 19930216