GB2062641B - Anti inflammatory 17-chloroethynyl-11,17-dihydroxy androst-4-en-3-ones and derivatives thereof - Google Patents
Anti inflammatory 17-chloroethynyl-11,17-dihydroxy androst-4-en-3-ones and derivatives thereofInfo
- Publication number
- GB2062641B GB2062641B GB8034750A GB8034750A GB2062641B GB 2062641 B GB2062641 B GB 2062641B GB 8034750 A GB8034750 A GB 8034750A GB 8034750 A GB8034750 A GB 8034750A GB 2062641 B GB2062641 B GB 2062641B
- Authority
- GB
- United Kingdom
- Prior art keywords
- chloroethynyl
- androst
- dihydroxy
- ones
- derivatives
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- MSEZLHAVPJYYIQ-VMXHOPILSA-N (8s,9s,10r,13s,14s)-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one Chemical class C1CC2=CC(=O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CCC[C@@]1(C)CC2 MSEZLHAVPJYYIQ-VMXHOPILSA-N 0.000 title 1
- 230000003110 anti-inflammatory effect Effects 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
- C07J1/0003—Androstane derivatives
- C07J1/0033—Androstane derivatives substituted in position 17 alfa and 17 beta
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
- C07J1/0003—Androstane derivatives
- C07J1/0011—Androstane derivatives substituted in position 17 by a keto group
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Rheumatology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pain & Pain Management (AREA)
- Steroid Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7926625A FR2468617A1 (fr) | 1979-10-26 | 1979-10-26 | Nouveaux derives acetyleniques chlores de l'androst-4-ene leur procede de preparation, et leur application a titre de medicament et les compositions pharmaceutiques les renfermant |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| GB2062641A GB2062641A (en) | 1981-05-28 |
| GB2062641B true GB2062641B (en) | 1983-09-01 |
Family
ID=9231089
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB8034750A Expired GB2062641B (en) | 1979-10-26 | 1980-10-24 | Anti inflammatory 17-chloroethynyl-11,17-dihydroxy androst-4-en-3-ones and derivatives thereof |
Country Status (7)
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2187522A1 (en) * | 1994-05-09 | 1995-11-16 | John Gregory Reid | Synthesis of 17.beta.-cyano-3-ethoxy-17.alpha.-hydroxy-6-methylandrosta-3,5,9(11)-triene |
| US7698831B2 (en) * | 2008-03-19 | 2010-04-20 | Zashiki-Warashi Manufacturing Inc. | Tile spacer and holder therefor |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2636405C2 (de) * | 1976-08-12 | 1982-07-08 | Schering Ag, 1000 Berlin Und 4619 Bergkamen | Δ↑1↑↑5↑-17α-Chloräthinyl- und -Propinylsteroide der Östranreihe, Verfahren zu ihrer Herstellung sowie diese enthaltende pharmazeutische Präparate |
| SE7801152L (sv) * | 1977-02-22 | 1978-08-23 | Roussel Uclaf | Sett att framstella 17alfa-acetylen-derivat av androst-4-en |
| FR2383967A1 (fr) * | 1977-03-18 | 1978-10-13 | Roussel Uclaf | Nouveaux derives 17 a-acetyleniques de l'androst 4-ene, leur procede de preparation et leur application comme medicament |
| FR2433536A1 (fr) * | 1978-08-16 | 1980-03-14 | Roussel Uclaf | Nouveaux derives de l'androst 4-ene, leur procede de preparation et leur application comme medicament |
-
1979
- 1979-10-26 FR FR7926625A patent/FR2468617A1/fr active Granted
-
1980
- 1980-10-09 US US06/195,647 patent/US4303654A/en not_active Expired - Lifetime
- 1980-10-24 IT IT49999/80A patent/IT1146199B/it active
- 1980-10-24 DE DE19803040200 patent/DE3040200A1/de active Granted
- 1980-10-24 JP JP14823780A patent/JPS5671100A/ja active Granted
- 1980-10-24 CH CH795080A patent/CH646983A5/fr not_active IP Right Cessation
- 1980-10-24 GB GB8034750A patent/GB2062641B/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| JPH0125759B2 (US06312121-20011106-C00033.png) | 1989-05-19 |
| IT1146199B (it) | 1986-11-12 |
| CH646983A5 (fr) | 1984-12-28 |
| FR2468617B1 (US06312121-20011106-C00033.png) | 1982-10-08 |
| FR2468617A1 (fr) | 1981-05-08 |
| IT8049999A0 (it) | 1980-10-24 |
| DE3040200C2 (US06312121-20011106-C00033.png) | 1989-11-09 |
| DE3040200A1 (de) | 1981-05-07 |
| JPS5671100A (en) | 1981-06-13 |
| GB2062641A (en) | 1981-05-28 |
| US4303654A (en) | 1981-12-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PCNP | Patent ceased through non-payment of renewal fee |
Effective date: 19931024 |