GB2053206B - Process for manufacturing racemic 5-aryl hydantoins and products thereof - Google Patents

Process for manufacturing racemic 5-aryl hydantoins and products thereof

Info

Publication number
GB2053206B
GB2053206B GB8018699A GB8018699A GB2053206B GB 2053206 B GB2053206 B GB 2053206B GB 8018699 A GB8018699 A GB 8018699A GB 8018699 A GB8018699 A GB 8018699A GB 2053206 B GB2053206 B GB 2053206B
Authority
GB
United Kingdom
Prior art keywords
products
racemic
manufacturing
hydantoins
aryl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB8018699A
Other languages
English (en)
Other versions
GB2053206A (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis France
Original Assignee
Francaise Hoechst Ste
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Francaise Hoechst Ste filed Critical Francaise Hoechst Ste
Publication of GB2053206A publication Critical patent/GB2053206A/en
Application granted granted Critical
Publication of GB2053206B publication Critical patent/GB2053206B/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/72Two oxygen atoms, e.g. hydantoin
    • C07D233/76Two oxygen atoms, e.g. hydantoin with substituted hydrocarbon radicals attached to the third ring carbon atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/72Two oxygen atoms, e.g. hydantoin
    • C07D233/74Two oxygen atoms, e.g. hydantoin with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to other ring members
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/72Two oxygen atoms, e.g. hydantoin
    • C07D233/76Two oxygen atoms, e.g. hydantoin with substituted hydrocarbon radicals attached to the third ring carbon atom
    • C07D233/78Radicals substituted by oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
GB8018699A 1979-06-07 1980-06-06 Process for manufacturing racemic 5-aryl hydantoins and products thereof Expired GB2053206B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7914562A FR2458546A1 (fr) 1979-06-07 1979-06-07 Procede de fabrication d'aryl-5 hydantoines racemiques et produits nouveaux en resultant

Publications (2)

Publication Number Publication Date
GB2053206A GB2053206A (en) 1981-02-04
GB2053206B true GB2053206B (en) 1983-02-23

Family

ID=9226319

Family Applications (1)

Application Number Title Priority Date Filing Date
GB8018699A Expired GB2053206B (en) 1979-06-07 1980-06-06 Process for manufacturing racemic 5-aryl hydantoins and products thereof

Country Status (2)

Country Link
FR (1) FR2458546A1 (enExample)
GB (1) GB2053206B (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4452806A (en) * 1982-11-01 1984-06-05 Pfizer Inc. Treating diabetic complications with 5-(substituted phenyl)hydantoins
US4457939A (en) * 1982-11-01 1984-07-03 Pfizer Inc. Aldose reductase inhibiting 5-(2-alkoxy-3-substituted phenyl)hydantoins
DE3368614D1 (en) * 1982-11-01 1987-02-05 Pfizer 5-(substituted phenyl) hydantoins
AT398199B (de) * 1992-11-27 1994-10-25 Chemie Linz Gmbh Verfahren zur herstellung von arylhydantoinen
DE4301244A1 (de) * 1993-01-19 1994-07-21 Chemie Linz Deutschland Verfahren zur Herstellung von Arylhydantoinen
AU2003282920A1 (en) 2002-10-04 2004-05-04 Bristol-Myers Squibb Company Hydantoin derivatives as inhibitors of matrix metalloproteinases and/or tnf-alpha converting enzyme (tace)

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2891069A (en) * 1957-07-01 1959-06-16 Spencer Chem Co 5-(2, 4-dihalophenyl) hydantoins
FR1326693A (fr) * 1961-05-08 1963-05-10 Spencer Chem Co Nouvelles compositions contenant des herbicides et un agent antagoniste de ces derniers et méthode pour le traitement des graines à l'aide desdites compositions
CH587903A5 (enExample) * 1973-05-07 1977-05-13 Ciba Geigy Ag

Also Published As

Publication number Publication date
FR2458546B1 (enExample) 1983-05-13
FR2458546A1 (fr) 1981-01-02
GB2053206A (en) 1981-02-04

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Legal Events

Date Code Title Description
PCNP Patent ceased through non-payment of renewal fee