GB2050386A - Method of producing a stable preparation having immunoglobulin-binding properties - Google Patents
Method of producing a stable preparation having immunoglobulin-binding propertiesInfo
- Publication number
- GB2050386A GB2050386A GB8029768A GB8029768A GB2050386A GB 2050386 A GB2050386 A GB 2050386A GB 8029768 A GB8029768 A GB 8029768A GB 8029768 A GB8029768 A GB 8029768A GB 2050386 A GB2050386 A GB 2050386A
- Authority
- GB
- United Kingdom
- Prior art keywords
- bacteria
- producing
- immunoglobulin
- binding properties
- stable preparation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/531—Production of immunochemical test materials
Landscapes
- Health & Medical Sciences (AREA)
- Immunology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Abstract
A method of producing a stable bacterial preparation having nonspecific immunoglobulinbinding properties. The bacteria, e.g. Staphylococcus aureus or Streptococcus pyogenes, with a nonspecific immunoglobulin-binding component, such as protein A of Staphylococcus aureus, on the surface of the bacteria, are grown in a substrate wherein the bacteria form the immunoglobulinbinding component. Then the bacteria are killed and lyophilized, the lyophilization step being carried out soon after killing of the bacteria. After reconstitution the lyophilized bacteria are used as reagent in immunological reactions.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE7712244A SE7712244L (en) | 1977-10-31 | 1977-10-31 | PROCEDURE FOR PREPARATION OF KILLED BACTERIA |
Publications (2)
Publication Number | Publication Date |
---|---|
GB2050386A true GB2050386A (en) | 1981-01-07 |
GB2050386B GB2050386B (en) | 1983-01-26 |
Family
ID=20332722
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB8029768A Expired GB2050386B (en) | 1977-10-31 | 1978-10-31 | Method of producing a stable preparation having immunoglobulin-binding properties |
Country Status (7)
Country | Link |
---|---|
EP (1) | EP0007953A1 (en) |
CH (1) | CH649385A5 (en) |
DE (1) | DE2857506A1 (en) |
FR (1) | FR2472612A1 (en) |
GB (1) | GB2050386B (en) |
SE (1) | SE7712244L (en) |
WO (1) | WO1979000256A1 (en) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB8618443D0 (en) * | 1986-07-29 | 1986-09-03 | Univ London | Monoclonal antibodies |
IL80313A0 (en) * | 1986-09-19 | 1987-01-30 | Yissum Res Dev Co | Immunoassay reagents,kits and methods |
US5085984A (en) * | 1987-12-10 | 1992-02-04 | University Of Florida Research Foundation, Inc. | Novel type VI bacterial Fc receptors |
US4948725A (en) * | 1987-12-10 | 1990-08-14 | University Of Florida Research Foundation, Inc. | Novel type VI bacterial Fc receptors |
US4977082A (en) * | 1987-12-10 | 1990-12-11 | University Of Florida Research Foundation, Inc. | Type VI bacterial FC receptors |
US5102788A (en) * | 1988-11-21 | 1992-04-07 | Hygeia Sciences, Inc. | Immunoassay including lyophilized reactant mixture |
US5424193A (en) * | 1993-02-25 | 1995-06-13 | Quidel Corporation | Assays employing dyed microorganism labels |
WO2008127457A2 (en) | 2006-12-06 | 2008-10-23 | Repligen Corporation | Nucleic acids encoding recombinant protein a |
-
1977
- 1977-10-31 SE SE7712244A patent/SE7712244L/en unknown
-
1978
- 1978-10-31 CH CH673680A patent/CH649385A5/en not_active IP Right Cessation
- 1978-10-31 GB GB8029768A patent/GB2050386B/en not_active Expired
- 1978-10-31 WO PCT/SE1978/000066 patent/WO1979000256A1/en unknown
- 1978-10-31 DE DE19782857506 patent/DE2857506A1/en not_active Withdrawn
-
1979
- 1979-05-22 EP EP19780900241 patent/EP0007953A1/en not_active Withdrawn
-
1980
- 1980-08-22 FR FR8018438A patent/FR2472612A1/en not_active Withdrawn
Also Published As
Publication number | Publication date |
---|---|
CH649385A5 (en) | 1985-05-15 |
WO1979000256A1 (en) | 1979-05-17 |
FR2472612A1 (en) | 1981-07-03 |
GB2050386B (en) | 1983-01-26 |
SE7712244L (en) | 1979-05-01 |
DE2857506A1 (en) | 1981-04-16 |
EP0007953A1 (en) | 1980-02-20 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PCNP | Patent ceased through non-payment of renewal fee |