GB2048873B - 9-deoxy-9-methylene-5,6-trans prostaglandins - Google Patents

9-deoxy-9-methylene-5,6-trans prostaglandins

Info

Publication number
GB2048873B
GB2048873B GB8013773A GB8013773A GB2048873B GB 2048873 B GB2048873 B GB 2048873B GB 8013773 A GB8013773 A GB 8013773A GB 8013773 A GB8013773 A GB 8013773A GB 2048873 B GB2048873 B GB 2048873B
Authority
GB
United Kingdom
Prior art keywords
prostaglandins
deoxy
trans
methylene
trans prostaglandins
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB8013773A
Other languages
English (en)
Other versions
GB2048873A (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pharmacia and Upjohn Co
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Publication of GB2048873A publication Critical patent/GB2048873A/en
Application granted granted Critical
Publication of GB2048873B publication Critical patent/GB2048873B/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C07C405/0008—Analogues having the carboxyl group in the side-chains replaced by other functional groups
    • C07C405/0016—Analogues having the carboxyl group in the side-chains replaced by other functional groups containing only hydroxy, etherified or esterified hydroxy groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C07C405/0008—Analogues having the carboxyl group in the side-chains replaced by other functional groups
    • C07C405/0041—Analogues having the carboxyl group in the side-chains replaced by other functional groups containing nitrogen

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
GB8013773A 1979-05-01 1980-04-25 9-deoxy-9-methylene-5,6-trans prostaglandins Expired GB2048873B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/035,144 US4220796A (en) 1979-05-01 1979-05-01 9-Deoxy-9-methylene-5,6-didehydro-PGF1 compounds

Publications (2)

Publication Number Publication Date
GB2048873A GB2048873A (en) 1980-12-17
GB2048873B true GB2048873B (en) 1983-05-25

Family

ID=21880926

Family Applications (1)

Application Number Title Priority Date Filing Date
GB8013773A Expired GB2048873B (en) 1979-05-01 1980-04-25 9-deoxy-9-methylene-5,6-trans prostaglandins

Country Status (7)

Country Link
US (1) US4220796A (OSRAM)
JP (1) JPS55147256A (OSRAM)
BE (1) BE883071A (OSRAM)
DE (1) DE3016559A1 (OSRAM)
FR (1) FR2455579A1 (OSRAM)
GB (1) GB2048873B (OSRAM)
NL (1) NL8002356A (OSRAM)

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4016184A (en) 1975-09-17 1977-04-05 The Upjohn Company 9-Deoxy-9,10-didehydro-PGD1 compounds
US4060534A (en) * 1976-01-23 1977-11-29 The Upjohn Company 9-Deoxy-9-methylene-PGF compounds
US4165436A (en) * 1978-04-05 1979-08-21 The Upjohn Company Trans-2,3-didehydro-9-deoxy-9-methylene-PGF compounds

Also Published As

Publication number Publication date
DE3016559A1 (de) 1980-11-13
NL8002356A (nl) 1980-11-04
BE883071A (fr) 1980-10-30
FR2455579A1 (fr) 1980-11-28
US4220796A (en) 1980-09-02
JPS55147256A (en) 1980-11-17
GB2048873A (en) 1980-12-17
FR2455579B1 (OSRAM) 1984-01-27

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Legal Events

Date Code Title Description
PCNP Patent ceased through non-payment of renewal fee