GB2036741B - Urethane derivatives of monensin a and b - Google Patents

Urethane derivatives of monensin a and b

Info

Publication number
GB2036741B
GB2036741B GB7941025A GB7941025A GB2036741B GB 2036741 B GB2036741 B GB 2036741B GB 7941025 A GB7941025 A GB 7941025A GB 7941025 A GB7941025 A GB 7941025A GB 2036741 B GB2036741 B GB 2036741B
Authority
GB
United Kingdom
Prior art keywords
derivatives
urethane derivatives
monensin
urethane
acylaryl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB7941025A
Other versions
GB2036741A (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/077,415 external-priority patent/US4263427A/en
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of GB2036741A publication Critical patent/GB2036741A/en
Application granted granted Critical
Publication of GB2036741B publication Critical patent/GB2036741B/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/01—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing oxygen
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/195—Antibiotics
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/18—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
    • C12P17/181—Heterocyclic compounds containing oxygen atoms as the only ring heteroatoms in the condensed system, e.g. Salinomycin, Septamycin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/44—Preparation of O-glycosides, e.g. glucosides
    • C12P19/445—The saccharide radical is condensed with a heterocyclic radical, e.g. everninomycin, papulacandin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/465—Streptomyces

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Polymers & Plastics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Animal Husbandry (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Food Science & Technology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Steroid Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Urethane derivatives of the formula <IMAGE> wherein R<1> is aryl, alkylaryl, haloaryl, nitroaryl, alkoxyaryl, aryloxyaryl acylaryl, alkyl, cycloalkyl, arylalkyl, haloarylalkyl or arylcycloalkyl and R<2> is methyl or ethyl, and their pharmaceutically acceptable salts. Moreover, the manufacture of the above urethane derivatives as well as compositions containing same. Also the use of these derivatives for the treatment or prophylaxis of diseases and to promote animal growth.
GB7941025A 1978-11-29 1979-11-28 Urethane derivatives of monensin a and b Expired GB2036741B (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US96456478A 1978-11-29 1978-11-29
US7281879A 1979-09-05 1979-09-05
US06/077,415 US4263427A (en) 1978-11-29 1979-09-20 Monensin urethane derivatives

Publications (2)

Publication Number Publication Date
GB2036741A GB2036741A (en) 1980-07-02
GB2036741B true GB2036741B (en) 1983-04-13

Family

ID=27372164

Family Applications (1)

Application Number Title Priority Date Filing Date
GB7941025A Expired GB2036741B (en) 1978-11-29 1979-11-28 Urethane derivatives of monensin a and b

Country Status (16)

Country Link
EP (1) EP0011859B1 (en)
AT (1) ATE2081T1 (en)
AU (1) AU531276B2 (en)
CA (1) CA1128505A (en)
DE (1) DE2964383D1 (en)
ES (1) ES8100255A1 (en)
FI (1) FI66386C (en)
GB (1) GB2036741B (en)
HK (1) HK70283A (en)
IE (1) IE48999B1 (en)
IL (1) IL58785A (en)
KE (1) KE3322A (en)
MY (1) MY8400342A (en)
NO (1) NO152134C (en)
NZ (1) NZ192228A (en)
PH (1) PH16764A (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4542027A (en) * 1984-02-23 1985-09-17 Syntex (U.S.A.) Inc. Laidlomycin phenylcarbamate
FR2570378B1 (en) * 1984-09-19 1987-05-22 Sanofi Sa NOVEL POLYETHER IONOPHORE, PROCESS FOR OBTAINING SAME, AND VETERINARY FOOD OR THERAPEUTIC COMPOSITIONS CONTAINING THE SAME
US5217993A (en) * 1992-07-20 1993-06-08 Eli Lilly And Company Monensin derivatives
DE60136067D1 (en) * 2000-04-26 2008-11-20 Meiji Seika Kaisha MIXTURES FOR THE TREATMENT OR PREVENTION OF MALARIA AND METHOD FOR THE TREATMENT OF MALARIA

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3501568A (en) * 1964-09-28 1970-03-17 Lilly Co Eli Novel antibiotic a3823 complex and process for production thereof
US3839557A (en) * 1972-01-24 1974-10-01 Lilly Co Eli Antibiotics monensin and a204 for improving ruminant feed efficiency
BE794487A (en) * 1972-01-24 1973-05-16 Lilly Co Eli IMPROVING THE USE OF FOOD IN RUMINANTS
US4027034A (en) * 1974-05-20 1977-05-31 Hoffmann-La Roche Inc. Method of combatting swine dysentery
US4058620A (en) * 1974-07-19 1977-11-15 Hoffmann-La Roche Inc. Therapeutic agents for improving cardiovascular function
US3995027A (en) * 1975-06-04 1976-11-30 Eli Lilly And Company Anti-viral method in animals
US4061755A (en) * 1976-03-25 1977-12-06 Eli Lilly And Company Coccidiocidal combination of monensin and metichlorpindol
US4075323A (en) * 1976-03-25 1978-02-21 Eli Lilly And Company Coccidiocidal combinations

Also Published As

Publication number Publication date
ATE2081T1 (en) 1983-01-15
KE3322A (en) 1983-09-16
EP0011859B1 (en) 1982-12-22
GB2036741A (en) 1980-07-02
PH16764A (en) 1984-02-15
IE792287L (en) 1980-05-29
MY8400342A (en) 1984-12-31
ES486399A0 (en) 1980-11-01
NZ192228A (en) 1985-02-28
ES8100255A1 (en) 1980-11-01
HK70283A (en) 1983-12-30
NO152134C (en) 1985-08-07
NO152134B (en) 1985-04-29
CA1128505A (en) 1982-07-27
AU531276B2 (en) 1983-08-18
AU5272879A (en) 1980-06-19
FI66386B (en) 1984-06-29
DE2964383D1 (en) 1983-01-27
IE48999B1 (en) 1985-07-10
FI793705A (en) 1980-05-30
EP0011859A1 (en) 1980-06-11
IL58785A (en) 1983-05-15
NO793876L (en) 1980-05-30
FI66386C (en) 1984-10-10
IL58785A0 (en) 1980-02-29

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Legal Events

Date Code Title Description
PCNP Patent ceased through non-payment of renewal fee