GB2034718B - Prolyl-phenylalanylarginine derivatives process for their preparation and their use for measuring enzyme activity - Google Patents
Prolyl-phenylalanylarginine derivatives process for their preparation and their use for measuring enzyme activityInfo
- Publication number
- GB2034718B GB2034718B GB7937424A GB7937424A GB2034718B GB 2034718 B GB2034718 B GB 2034718B GB 7937424 A GB7937424 A GB 7937424A GB 7937424 A GB7937424 A GB 7937424A GB 2034718 B GB2034718 B GB 2034718B
- Authority
- GB
- United Kingdom
- Prior art keywords
- phenylalanylarginine
- prolyl
- preparation
- enzyme activity
- measuring enzyme
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0821—Tripeptides with the first amino acid being heterocyclic, e.g. His, Pro, Trp
- C07K5/0823—Tripeptides with the first amino acid being heterocyclic, e.g. His, Pro, Trp and Pro-amino acid; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
- C12Q1/37—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving peptidase or proteinase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/56—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving blood clotting factors, e.g. involving thrombin, thromboplastin, fibrinogen
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2334/00—O-linked chromogens for determinations of hydrolase enzymes, e.g. glycosidases, phosphatases, esterases
- C12Q2334/30—Naphthol derivatives, e.g. alpha-naphthyl-esters, i.e. alpha-NE, beta-naphthyl-esters, i.e. beta-NE
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/90—Enzymes; Proenzymes
- G01N2333/914—Hydrolases (3)
- G01N2333/948—Hydrolases (3) acting on peptide bonds (3.4)
- G01N2333/95—Proteinases, i.e. endopeptidases (3.4.21-3.4.99)
- G01N2333/964—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue
- G01N2333/96425—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals
- G01N2333/96427—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals in general
- G01N2333/9643—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals in general with EC number
- G01N2333/96433—Serine endopeptidases (3.4.21)
- G01N2333/96441—Serine endopeptidases (3.4.21) with definite EC number
- G01N2333/96455—Kallikrein (3.4.21.34; 3.4.21.35)
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Microbiology (AREA)
- Immunology (AREA)
- Biotechnology (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Neurosurgery (AREA)
- Hematology (AREA)
- Medicinal Chemistry (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP13339378A JPS5827784B2 (en) | 1978-10-30 | 1978-10-30 | amino acid derivative |
Publications (2)
Publication Number | Publication Date |
---|---|
GB2034718A GB2034718A (en) | 1980-06-11 |
GB2034718B true GB2034718B (en) | 1983-01-06 |
Family
ID=15103689
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB7937424A Expired GB2034718B (en) | 1978-10-30 | 1979-10-29 | Prolyl-phenylalanylarginine derivatives process for their preparation and their use for measuring enzyme activity |
Country Status (4)
Country | Link |
---|---|
JP (1) | JPS5827784B2 (en) |
DE (1) | DE2943582C2 (en) |
FR (1) | FR2440356A1 (en) |
GB (1) | GB2034718B (en) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4335203A (en) * | 1980-07-10 | 1982-06-15 | The Regents Of The University Of California | Method for identifying potential contrast media reactors |
US4386075A (en) * | 1982-02-17 | 1983-05-31 | Smithkline Beckman Corporation | Renally active tetrapeptides |
US4387049A (en) * | 1982-02-22 | 1983-06-07 | Smithkline Beckman Corporation | Adamantyl containing peptides |
JPS6117956A (en) * | 1984-07-04 | 1986-01-25 | Nitto Boseki Co Ltd | Novel substrate for measuring kallikrein in urine |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2527932C2 (en) * | 1974-07-02 | 1983-04-21 | Pentapharm AG, 4052 Basel | Acid addition salts of tripeptide derivatives and their use as substrates for the determination of plasma kallikrein |
-
1978
- 1978-10-30 JP JP13339378A patent/JPS5827784B2/en not_active Expired
-
1979
- 1979-10-29 DE DE19792943582 patent/DE2943582C2/en not_active Expired
- 1979-10-29 FR FR7926782A patent/FR2440356A1/en active Granted
- 1979-10-29 GB GB7937424A patent/GB2034718B/en not_active Expired
Also Published As
Publication number | Publication date |
---|---|
GB2034718A (en) | 1980-06-11 |
FR2440356A1 (en) | 1980-05-30 |
FR2440356B1 (en) | 1983-11-25 |
DE2943582A1 (en) | 1980-05-29 |
DE2943582C2 (en) | 1982-11-18 |
JPS5827784B2 (en) | 1983-06-11 |
JPS5559151A (en) | 1980-05-02 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PCNP | Patent ceased through non-payment of renewal fee |
Effective date: 19941029 |