GB2023583B - 3,7-disubstituted 3- cephem-4-carboxylic acid compounds and processes for the preparation thereof - Google Patents

3,7-disubstituted 3- cephem-4-carboxylic acid compounds and processes for the preparation thereof

Info

Publication number
GB2023583B
GB2023583B GB7905196A GB7905196A GB2023583B GB 2023583 B GB2023583 B GB 2023583B GB 7905196 A GB7905196 A GB 7905196A GB 7905196 A GB7905196 A GB 7905196A GB 2023583 B GB2023583 B GB 2023583B
Authority
GB
United Kingdom
Prior art keywords
cephem
disubstituted
processes
preparation
carboxylic acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB7905196A
Other versions
GB2023583A (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fujisawa Pharmaceutical Co Ltd
Original Assignee
Fujisawa Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/887,999 external-priority patent/US4279818A/en
Application filed by Fujisawa Pharmaceutical Co Ltd filed Critical Fujisawa Pharmaceutical Co Ltd
Publication of GB2023583A publication Critical patent/GB2023583A/en
Application granted granted Critical
Publication of GB2023583B publication Critical patent/GB2023583B/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
    • C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D257/04—Five-membered rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/38—Nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/587—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with aliphatic hydrocarbon radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms, said aliphatic radicals being substituted in the alpha-position to the ring by a hetero atom, e.g. with m >= 0, Z being a singly or a doubly bound hetero atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/18—7-Aminocephalosporanic or substituted 7-aminocephalosporanic acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)
GB7905196A 1978-02-15 1979-02-14 3,7-disubstituted 3- cephem-4-carboxylic acid compounds and processes for the preparation thereof Expired GB2023583B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US87784878A 1978-02-15 1978-02-15
US05/887,999 US4279818A (en) 1976-04-12 1978-03-20 Syn-isomers of 7-[2-alkoxyimino-2-(2-amino-thiazol-4-yl)acetamido]-3-[nitrobenzoyl-, or benzoyl-oxymethyl]-3-cephem-4-carboxylic acid

Publications (2)

Publication Number Publication Date
GB2023583A GB2023583A (en) 1980-01-03
GB2023583B true GB2023583B (en) 1982-07-28

Family

ID=27128459

Family Applications (1)

Application Number Title Priority Date Filing Date
GB7905196A Expired GB2023583B (en) 1978-02-15 1979-02-14 3,7-disubstituted 3- cephem-4-carboxylic acid compounds and processes for the preparation thereof

Country Status (1)

Country Link
GB (1) GB2023583B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0830051B2 (en) * 1986-05-21 1996-03-27 武田薬品工業株式会社 Process for producing 4-halogeno-2-substituted oxyimino-3-oxobutyric acid ester or amide

Also Published As

Publication number Publication date
GB2023583A (en) 1980-01-03

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Legal Events

Date Code Title Description
PCNP Patent ceased through non-payment of renewal fee