GB2021119A - Penicillin V-acylase - Google Patents

Penicillin V-acylase

Info

Publication number
GB2021119A
GB2021119A GB7913384A GB7913384A GB2021119A GB 2021119 A GB2021119 A GB 2021119A GB 7913384 A GB7913384 A GB 7913384A GB 7913384 A GB7913384 A GB 7913384A GB 2021119 A GB2021119 A GB 2021119A
Authority
GB
United Kingdom
Prior art keywords
acylase
penicillin
strain
apa
nrrl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
GB7913384A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novo Nordisk AS
Original Assignee
Novo Industri AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Industri AS filed Critical Novo Industri AS
Priority to GB7913384A priority Critical patent/GB2021119A/en
Publication of GB2021119A publication Critical patent/GB2021119A/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/78—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
    • C12N9/80—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5) acting on amide bonds in linear amides (3.5.1)
    • C12N9/84—Penicillin amidase (3.5.1.11)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Mycology (AREA)
  • Molecular Biology (AREA)
  • Enzymes And Modification Thereof (AREA)

Abstract

A penicillin V-acylase is produced by cultivation of a bacterial strain having the general characteristics of the strain deposited in NRRL with the number 11240, as well as variants or mutants of such a strain in which the ability to produce penicillin V-acylase is retained. A method of producing said penicillin V-acylase and the use of such a penicillin V-acylase in the preparation of 6-APA and 7-ACA and homologs thereof is described.
GB7913384A 1978-04-19 1979-04-18 Penicillin V-acylase Withdrawn GB2021119A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
GB7913384A GB2021119A (en) 1978-04-19 1979-04-18 Penicillin V-acylase

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB1552278 1978-04-19
GB7913384A GB2021119A (en) 1978-04-19 1979-04-18 Penicillin V-acylase

Publications (1)

Publication Number Publication Date
GB2021119A true GB2021119A (en) 1979-11-28

Family

ID=26251353

Family Applications (1)

Application Number Title Priority Date Filing Date
GB7913384A Withdrawn GB2021119A (en) 1978-04-19 1979-04-18 Penicillin V-acylase

Country Status (1)

Country Link
GB (1) GB2021119A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5268271A (en) * 1989-12-12 1993-12-07 Cosejo Superior De Invetigaciones Certificas Method for the synthesis of semi-synthetic antibiotics in thermodynamically controlled water-cosolvent organic miscible apolar systems by using penicillin G acylase

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5268271A (en) * 1989-12-12 1993-12-07 Cosejo Superior De Invetigaciones Certificas Method for the synthesis of semi-synthetic antibiotics in thermodynamically controlled water-cosolvent organic miscible apolar systems by using penicillin G acylase

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Legal Events

Date Code Title Description
WAP Application withdrawn, taken to be withdrawn or refused ** after publication under section 16(1)