GB202011871D0 - Composition and method - Google Patents
Composition and methodInfo
- Publication number
- GB202011871D0 GB202011871D0 GBGB2011871.7A GB202011871A GB202011871D0 GB 202011871 D0 GB202011871 D0 GB 202011871D0 GB 202011871 A GB202011871 A GB 202011871A GB 202011871 D0 GB202011871 D0 GB 202011871D0
- Authority
- GB
- United Kingdom
- Prior art keywords
- composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
- C12N15/90—Stable introduction of foreign DNA into chromosome
- C12N15/902—Stable introduction of foreign DNA into chromosome using homologous recombination
- C12N15/907—Stable introduction of foreign DNA into chromosome using homologous recombination in mammalian cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2750/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
- C12N2750/00011—Details
- C12N2750/14011—Parvoviridae
- C12N2750/14111—Dependovirus, e.g. adenoassociated viruses
- C12N2750/14122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2750/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
- C12N2750/00011—Details
- C12N2750/14011—Parvoviridae
- C12N2750/14111—Dependovirus, e.g. adenoassociated viruses
- C12N2750/14141—Use of virus, viral particle or viral elements as a vector
- C12N2750/14143—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2750/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
- C12N2750/00011—Details
- C12N2750/14011—Parvoviridae
- C12N2750/14111—Dependovirus, e.g. adenoassociated viruses
- C12N2750/14141—Use of virus, viral particle or viral elements as a vector
- C12N2750/14145—Special targeting system for viral vectors
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2750/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
- C12N2750/00011—Details
- C12N2750/14011—Parvoviridae
- C12N2750/14111—Dependovirus, e.g. adenoassociated viruses
- C12N2750/14171—Demonstrated in vivo effect
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Virology (AREA)
- Medicinal Chemistry (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Cell Biology (AREA)
- Mycology (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Epidemiology (AREA)
Priority Applications (10)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB2011871.7A GB202011871D0 (en) | 2020-07-30 | 2020-07-30 | Composition and method |
| PCT/GB2021/051985 WO2022023773A1 (en) | 2020-07-30 | 2021-07-30 | Composition and method |
| JP2023505948A JP7841821B2 (ja) | 2020-07-30 | 2021-07-30 | 組成物および方法 |
| BR112023001611A BR112023001611A2 (pt) | 2020-07-30 | 2021-07-30 | Proteína do capsídeo de vírus adenoassociado (aav), ácido nucleico, dna recombinante, célula hospedeira, partícula viral, animal transgênico, composição farmacêutica, proteína do capsídeo e método de direcionamento para a microglia ou macrófagos cerebrais |
| US18/007,378 US20230295237A1 (en) | 2020-07-30 | 2021-07-30 | Composition and method |
| CA3190289A CA3190289A1 (en) | 2020-07-30 | 2021-07-30 | Composition and method |
| KR1020237007325A KR20230041820A (ko) | 2020-07-30 | 2021-07-30 | 조성물 및 방법 |
| CN202180066253.7A CN116406427A (zh) | 2020-07-30 | 2021-07-30 | 组合物和方法 |
| EP21756024.2A EP4188940A1 (en) | 2020-07-30 | 2021-07-30 | Composition and method |
| AU2021319154A AU2021319154A1 (en) | 2020-07-30 | 2021-07-30 | Composition and method |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB2011871.7A GB202011871D0 (en) | 2020-07-30 | 2020-07-30 | Composition and method |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB202011871D0 true GB202011871D0 (en) | 2020-09-16 |
Family
ID=72425275
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GBGB2011871.7A Ceased GB202011871D0 (en) | 2020-07-30 | 2020-07-30 | Composition and method |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20230295237A1 (https=) |
| EP (1) | EP4188940A1 (https=) |
| JP (1) | JP7841821B2 (https=) |
| KR (1) | KR20230041820A (https=) |
| CN (1) | CN116406427A (https=) |
| AU (1) | AU2021319154A1 (https=) |
| BR (1) | BR112023001611A2 (https=) |
| CA (1) | CA3190289A1 (https=) |
| GB (1) | GB202011871D0 (https=) |
| WO (1) | WO2022023773A1 (https=) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE202022002866U1 (de) | 2021-04-01 | 2024-03-20 | The Regents Of The University Of California | Genetische Modifikation von Säugetierzellen zur Verleihung von Resistenz gegen CSF1R-Antagonisten |
| CA3254570A1 (en) * | 2022-03-24 | 2023-09-28 | Capsida, Inc. | ADENE-ASSOCIATED VIRUS COMPOSITIONS WITH INCREASED CARDIAC ENRICHEMENT |
| AU2023267474A1 (en) * | 2022-05-13 | 2024-12-05 | Children's Medical Research Institute | Adeno-associated virus capsids |
| US20260108560A1 (en) * | 2022-07-13 | 2026-04-23 | The Regents Of The University Of California | Transplanting stem cell-derived microglia to treat leukodystrophies |
| CN121311596A (zh) * | 2023-04-07 | 2026-01-09 | 4D分子治疗有限公司 | 用于治疗补体病症的aav变体 |
| CN118480097B (zh) * | 2023-09-20 | 2024-11-05 | 广州派真生物技术有限公司 | 腺相关病毒突变体及其应用 |
| CN117660370B (zh) * | 2023-11-08 | 2025-03-21 | 中国人民解放军空军军医大学 | 一种重组腺相关病毒、抗炎药物及其在脓毒性脑病治疗中的应用 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9585971B2 (en) * | 2013-09-13 | 2017-03-07 | California Institute Of Technology | Recombinant AAV capsid protein |
| KR102423442B1 (ko) * | 2015-12-11 | 2022-07-20 | 캘리포니아 인스티튜트 오브 테크놀로지 | 아데노-관련 바이러스를 지시하기 위한 타겟팅 펩타이드 |
| JP7221275B2 (ja) * | 2017-08-03 | 2023-02-13 | ボイジャー セラピューティクス インコーポレイテッド | Ａａｖを送達するための組成物および方法 |
| US20210277418A1 (en) * | 2018-08-03 | 2021-09-09 | Voyager Therapeutics, Inc. | Aav variants with enhanced tropism |
-
2020
- 2020-07-30 GB GBGB2011871.7A patent/GB202011871D0/en not_active Ceased
-
2021
- 2021-07-30 CA CA3190289A patent/CA3190289A1/en active Pending
- 2021-07-30 AU AU2021319154A patent/AU2021319154A1/en active Pending
- 2021-07-30 JP JP2023505948A patent/JP7841821B2/ja active Active
- 2021-07-30 BR BR112023001611A patent/BR112023001611A2/pt unknown
- 2021-07-30 US US18/007,378 patent/US20230295237A1/en active Pending
- 2021-07-30 EP EP21756024.2A patent/EP4188940A1/en active Pending
- 2021-07-30 KR KR1020237007325A patent/KR20230041820A/ko active Pending
- 2021-07-30 WO PCT/GB2021/051985 patent/WO2022023773A1/en not_active Ceased
- 2021-07-30 CN CN202180066253.7A patent/CN116406427A/zh active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| KR20230041820A (ko) | 2023-03-24 |
| BR112023001611A2 (pt) | 2023-02-14 |
| WO2022023773A1 (en) | 2022-02-03 |
| CA3190289A1 (en) | 2022-02-03 |
| EP4188940A1 (en) | 2023-06-07 |
| AU2021319154A1 (en) | 2023-03-23 |
| JP7841821B2 (ja) | 2026-04-07 |
| JP2023535620A (ja) | 2023-08-18 |
| US20230295237A1 (en) | 2023-09-21 |
| CN116406427A (zh) | 2023-07-07 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| AT | Applications terminated before publication under section 16(1) |