GB202005184D0 - Method - Google Patents

Method

Info

Publication number
GB202005184D0
GB202005184D0 GBGB2005184.3A GB202005184A GB202005184D0 GB 202005184 D0 GB202005184 D0 GB 202005184D0 GB 202005184 A GB202005184 A GB 202005184A GB 202005184 D0 GB202005184 D0 GB 202005184D0
Authority
GB
United Kingdom
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
GBGB2005184.3A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Autolus Ltd
Original Assignee
Autolus Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Autolus Ltd filed Critical Autolus Ltd
Priority to GBGB2005184.3A priority Critical patent/GB202005184D0/en
Publication of GB202005184D0 publication Critical patent/GB202005184D0/en
Priority to PCT/GB2021/050854 priority patent/WO2021205166A1/en
Priority to EP21717956.3A priority patent/EP4132966A1/en
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • C07K14/7051—T-cell receptor (TcR)-CD3 complex
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034—Isolating an individual clone by screening libraries
    • C12N15/1079—Screening libraries by altering the phenotype or phenotypic trait of the host
    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B30/00—Methods of screening libraries
    • C40B30/06—Methods of screening libraries by measuring effects on living organisms, tissues or cells
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/03—Fusion polypeptide containing a localisation/targetting motif containing a transmembrane segment
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value
    • G01N2500/10—Screening for compounds of potential therapeutic value involving cells
GBGB2005184.3A 2020-04-08 2020-04-08 Method Ceased GB202005184D0 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
GBGB2005184.3A GB202005184D0 (en) 2020-04-08 2020-04-08 Method
PCT/GB2021/050854 WO2021205166A1 (en) 2020-04-08 2021-04-07 A method of generating a library of populations of cells comprising a transgene integrated into the genome at a target locus
EP21717956.3A EP4132966A1 (en) 2020-04-08 2021-04-07 A method of generating a library of populations of cells comprising a transgene integrated into the genome at a target locus

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB2005184.3A GB202005184D0 (en) 2020-04-08 2020-04-08 Method

Publications (1)

Publication Number Publication Date
GB202005184D0 true GB202005184D0 (en) 2020-05-20

Family

ID=70768798

Family Applications (1)

Application Number Title Priority Date Filing Date
GBGB2005184.3A Ceased GB202005184D0 (en) 2020-04-08 2020-04-08 Method

Country Status (3)

Country Link
EP (1) EP4132966A1 (en)
GB (1) GB202005184D0 (en)
WO (1) WO2021205166A1 (en)

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2018073393A2 (en) * 2016-10-19 2018-04-26 Cellectis Tal-effector nuclease (talen) -modified allogenic cells suitable for therapy
JP2020529834A (en) * 2017-06-30 2020-10-15 プレシジョン バイオサイエンシズ，インク． Genetically modified T cells containing modified introns of the T cell receptor alpha gene
WO2019020733A1 (en) * 2017-07-26 2019-01-31 Cellectis Methods of antigen-dependent chimeric antigen receptor (car) immune cell selection
EP3775229A4 (en) * 2018-03-27 2021-12-15 The Trustees Of The University Of Pennsylvania Modified immune cells having enhanced function and methods for screening for same
KR20210020873A (en) * 2018-04-05 2021-02-24 주노 쎄러퓨티크스 인코퍼레이티드 Τ cells expressing recombinant receptors, related polynucleotides and methods
CN112105420A (en) * 2018-05-11 2020-12-18 克里斯珀医疗股份公司 Methods and compositions for treating cancer

Non-Patent Citations (13)

* Cited by examiner, † Cited by third party
Title
BERDIEN, B. ET AL., GENE THER., vol. 21, 2014, pages 539 - 548
DAI, X. ET AL., NAT. METHODS, vol. 16, 2019, pages 247 - 254
EYQUEM, J. ET AL., NATURE, vol. 543, 2017, pages 113 - 117
GHORASHIAN, S. ET AL., BR. J. HAEMATOL., vol. 169, no. 4, 2015, pages 463 - 478
KARRAN, P., BR. MED. BULL., vol. 79-80, 2006, pages 153 - 170
KNIPPING, F. ET AL., METHODS CLIN. DEV., vol. 4, 2017, pages 213 - 224
LIAO, S. ET AL., NUCLEIC ACIDS RES., vol. 43, no. 20, 2015, pages e134
MACLEOD, D. T. ET AL., MOL. THER., vol. 25, 2017, pages 949 - 961
OSBORN, M. J. ET AL., MOL. THER., vol. 24, 2016, pages 570 - 581
POIROT, L. ET AL., CANCER RES., vol. 75, 2015, pages 3853 - 3864
ROTH, T. L. ET AL., NATURE, vol. 559, 2018, pages 405 - 409
SWANN, P. F. ET AL., SCIENCE, vol. 273, 1996, pages 1109 - 1111
TORIKAI, H. ET AL., BLOOD, vol. 119, 2012, pages 5697 - 5705

Also Published As

Publication number Publication date
EP4132966A1 (en) 2023-02-15
WO2021205166A1 (en) 2021-10-14

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Legal Events

Date Code Title Description
AT Applications terminated before publication under section 16(1)