GB201900529D0 - Bicyclic peptide ligands specific for CD38 - Google Patents
Bicyclic peptide ligands specific for CD38Info
- Publication number
- GB201900529D0 GB201900529D0 GBGB1900529.7A GB201900529A GB201900529D0 GB 201900529 D0 GB201900529 D0 GB 201900529D0 GB 201900529 A GB201900529 A GB 201900529A GB 201900529 D0 GB201900529 D0 GB 201900529D0
- Authority
- GB
- United Kingdom
- Prior art keywords
- peptide ligands
- ligands specific
- bicyclic peptide
- bicyclic
- specific
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
- 102100031585 ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 Human genes 0.000 title 1
- 101000777636 Homo sapiens ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 Proteins 0.000 title 1
- 125000002619 bicyclic group Chemical group 0.000 title 1
- 239000003446 ligand Substances 0.000 title 1
- 108090000765 processed proteins & peptides Proteins 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
- A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Epoxy Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Saccharide Compounds (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Priority Applications (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB1900529.7A GB201900529D0 (en) | 2019-01-15 | 2019-01-15 | Bicyclic peptide ligands specific for CD38 |
| PCT/GB2020/050073 WO2020148529A1 (en) | 2019-01-15 | 2020-01-15 | Bicyclic peptide ligands specific for cd38 |
| CN202080019655.7A CN113543813B (zh) | 2019-01-15 | 2020-01-15 | Cd38特异性的双环肽配体 |
| EP20701837.5A EP3911365A1 (en) | 2019-01-15 | 2020-01-15 | Bicyclic peptide ligands specific for cd38 |
| US17/422,940 US20220064218A1 (en) | 2019-01-15 | 2020-01-15 | Bicyclic peptide ligands specific for cd38 |
| JP2021540842A JP7645801B2 (ja) | 2019-01-15 | 2020-01-15 | Ｃｄ３８に特異的な二環式ペプチドリガンド |
| JP2024185776A JP2025023938A (ja) | 2019-01-15 | 2024-10-22 | Ｃｄ３８に特異的な二環式ペプチドリガンド |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB1900529.7A GB201900529D0 (en) | 2019-01-15 | 2019-01-15 | Bicyclic peptide ligands specific for CD38 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB201900529D0 true GB201900529D0 (en) | 2019-03-06 |
Family
ID=65528180
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GBGB1900529.7A Ceased GB201900529D0 (en) | 2019-01-15 | 2019-01-15 | Bicyclic peptide ligands specific for CD38 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20220064218A1 (enExample) |
| EP (1) | EP3911365A1 (enExample) |
| JP (2) | JP7645801B2 (enExample) |
| CN (1) | CN113543813B (enExample) |
| GB (1) | GB201900529D0 (enExample) |
| WO (1) | WO2020148529A1 (enExample) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SI3215518T1 (sl) | 2014-10-29 | 2021-08-31 | Bicyclerd Limited | Biciklični peptidni ligandi, značilni za MT1-MMP |
| CN111183147B (zh) | 2017-08-04 | 2024-07-05 | 拜斯科技术开发有限公司 | Cd137特异性的双环肽配体 |
| WO2019162682A1 (en) | 2018-02-23 | 2019-08-29 | Bicycletx Limited | Multimeric bicyclic peptide ligands |
| US11180531B2 (en) | 2018-06-22 | 2021-11-23 | Bicycletx Limited | Bicyclic peptide ligands specific for Nectin-4 |
| GB201820325D0 (en) | 2018-12-13 | 2019-01-30 | Bicyclerd Ltd | Bicyclic peptide ligands specific for psma |
| GB201820288D0 (en) | 2018-12-13 | 2019-01-30 | Bicycle Tx Ltd | Bicycle peptide ligaands specific for MT1-MMP |
| GB201820295D0 (en) | 2018-12-13 | 2019-01-30 | Bicyclerd Ltd | Bicyclic peptide ligands specific for MT1-MMP |
| WO2020128526A1 (en) | 2018-12-21 | 2020-06-25 | Bicycletx Limited | Bicyclic peptide ligands specific for pd-l1 |
| TWI862640B (zh) | 2019-07-30 | 2024-11-21 | 英商拜西可泰克斯有限公司 | 異質雙環肽複合物 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2541436T3 (es) | 2004-02-06 | 2015-07-20 | Morphosys Ag | Anticuerpos humanos anti-CD38 y usos para ellos |
| ES2509959T5 (en) * | 2008-02-05 | 2024-12-19 | Bicyclerd Ltd | Methods and compositions |
| US20140274759A1 (en) * | 2013-03-15 | 2014-09-18 | Bicycle Therapeutics Limited | Modification of polypeptides |
| SI3215518T1 (sl) | 2014-10-29 | 2021-08-31 | Bicyclerd Limited | Biciklični peptidni ligandi, značilni za MT1-MMP |
| EP3288962A1 (en) * | 2015-04-28 | 2018-03-07 | Ecole Polytechnique Fédérale de Lausanne (EPFL) | Novel inhibitors of the enzyme activated factor xii (fxiia) |
| GB201600903D0 (en) * | 2016-01-18 | 2016-03-02 | Bicycle Therapeutics Ltd | Peptide derivaties |
| GB201600911D0 (en) * | 2016-01-18 | 2016-03-02 | Bicycle Therapeutics Ltd | Stabilized peptide derivatives |
| EP3645549A1 (en) * | 2017-06-26 | 2020-05-06 | BicycleRD Limited | Bicyclic peptide ligands with detectable moieties and uses thereof |
| GB201810320D0 (en) * | 2018-06-22 | 2018-08-08 | Bicycletx Ltd | Peptide ligands for binding to CD38 |
-
2019
- 2019-01-15 GB GBGB1900529.7A patent/GB201900529D0/en not_active Ceased
-
2020
- 2020-01-15 JP JP2021540842A patent/JP7645801B2/ja active Active
- 2020-01-15 CN CN202080019655.7A patent/CN113543813B/zh active Active
- 2020-01-15 WO PCT/GB2020/050073 patent/WO2020148529A1/en not_active Ceased
- 2020-01-15 EP EP20701837.5A patent/EP3911365A1/en active Pending
- 2020-01-15 US US17/422,940 patent/US20220064218A1/en active Pending
-
2024
- 2024-10-22 JP JP2024185776A patent/JP2025023938A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| JP2022517040A (ja) | 2022-03-03 |
| CN113543813A (zh) | 2021-10-22 |
| JP2025023938A (ja) | 2025-02-19 |
| US20220064218A1 (en) | 2022-03-03 |
| JP7645801B2 (ja) | 2025-03-14 |
| CN113543813B (zh) | 2024-03-29 |
| EP3911365A1 (en) | 2021-11-24 |
| WO2020148529A1 (en) | 2020-07-23 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| AT | Applications terminated before publication under section 16(1) |