GB201817902D0 - Methods and compositions - Google Patents

Methods and compositions

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Publication number
GB201817902D0
GB201817902D0 GBGB1817902.8A GB201817902A GB201817902D0 GB 201817902 D0 GB201817902 D0 GB 201817902D0 GB 201817902 A GB201817902 A GB 201817902A GB 201817902 D0 GB201817902 D0 GB 201817902D0
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GB
United Kingdom
Prior art keywords
compositions
methods
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
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GBGB1817902.8A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Imperial College of Science Technology and Medicine
Original Assignee
Imperial Innovations Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Imperial Innovations Ltd filed Critical Imperial Innovations Ltd
Priority to GBGB1817902.8A priority Critical patent/GB201817902D0/en
Publication of GB201817902D0 publication Critical patent/GB201817902D0/en
Ceased legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/67—General methods for enhancing the expression
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70—Vectors or expression systems specially adapted for E. coli
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
    • C12N15/815—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts for yeasts other than Saccharomyces
GBGB1817902.8A 2018-11-01 2018-11-01 Methods and compositions Ceased GB201817902D0 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
GBGB1817902.8A GB201817902D0 (en) 2018-11-01 2018-11-01 Methods and compositions

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB1817902.8A GB201817902D0 (en) 2018-11-01 2018-11-01 Methods and compositions

Publications (1)

Publication Number Publication Date
GB201817902D0 true GB201817902D0 (en) 2018-12-19

Family

ID=64655500

Family Applications (1)

Application Number Title Priority Date Filing Date
GBGB1817902.8A Ceased GB201817902D0 (en) 2018-11-01 2018-11-01 Methods and compositions

Country Status (1)

Country Link
GB (1) GB201817902D0 (en)

Non-Patent Citations (52)

* Cited by examiner, † Cited by third party
Title
"NCBI", Database accession no. NC 000913.3
"NCBI", Database accession no. NC 010473.1
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CERONI ET AL., NATURE METHODS, 2015
CERONI, F.; ALGAR, R.; STAN, G.-B.; ELLIS, T.: "Quantifying cellular capacity identifies gene expression designs with reduced burden", NAT METH, vol. 12, 2015, pages 415 - 418
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EDGAR ET AL., NCBI'S GENE EXPRESSION OMNIBUS, 2002
EDGAR, R ET AL.: "Gene Expression Omnibus: NCBI gene expression and hybridization array data repository", NUCLEIC ACIDS RES., vol. 30, no. 1, 2002, pages 207 - 10
EI-SAMAD, H.; KURATA, H.; DOYLE, J.C.; GROSS, C.A.; KHAMMASH, M.: "Surviving heat shock: control strategies for robustness and performance", PROC. NATL. ACAD. SCI. USA, vol. 102, 2005, pages 2736 - 2741
FARASAT, I.; SALIS, H.M.: "A biophysical model of CRISPR/Cas9 activity for rational design of genome editing and gene regulation", PLOS COMPUT. BIOL., vol. 12, 2016, pages e1004724, XP055462694, DOI: doi:10.1371/journal.pcbi.1004724
GERTZ, J. ET AL.: "Transposase mediated construction of RNA-seq libraries", GENOME RES., vol. 22, 2012, pages 134 - 141, XP055050772, DOI: doi:10.1101/gr.127373.111
GOROCHOWSKI, T. E.; AVCILAR-KUCUKGOZE, I.; BOVENBERG, R. A. L.; ROUBOS, J. A.; IGNATOVA, Z.: "A Minimal Model of Ribosome Allocation Dynamics Captures Trade-offs in Expression between Endogenous and Synthetic Genes", ACS SYNTH. BIOL., vol. 5, 2016, pages 710 - 720
GOROCHOWSKI, T.E. ET AL.: "Genetic circuit characterization and debugging using RNA-seq", MOL. SYST. BIOL., vol. 13, 2017, pages 952
GOROCHOWSKI, T.E.; AVCILAR-KUCUKGOZE, I.; BOVENBERG, R.A.L.; ROUBOS, J.A.; IGNATOVA, Z.: "A minimal model of ribosome allocation dynamics captures trade-offs in expression between endogenous and synthetic genes", ACS SYNTH. BIOL., vol. 5, 2016, pages 710 - 720
GUISBERT, E.; HERMAN, C.; LU, C.Z.; GROSS, C.A.: "A chaperone network controls the heat shock response in E. coli", GENES DEV., vol. 18, 2004, pages 2812 - 2821
GUPTA, A.; REIZMAN, I.M.; REISCH, C.R.; PRATHER, K.L.J.: "Dynamic regulation of metabolic flux in engineered bacteria using a pathway-independent quorum-sensing circuit", NAT. BIOTECHNOL., vol. 35, 2017, pages 273 - 279
GYORGY, A. ET AL.: "Isocost lines describe the cellular economy of genetic circuits", BIOPHYS. J., vol. 109, 2015, pages 639 - 646, XP029251144, DOI: doi:10.1016/j.bpj.2015.06.034
HE, S. ET AL.: "Validation of two ribosomal RNA removal methods for microbial metatranscriptomics", NAT. METHODS, vol. 7, 2010, pages 807 - 812
HOUSER, J.R. ET AL.: "Controlled measurement and comparative analysis of cellular components in E. coli reveals broad regulatory changes in response to glucose starvation", PLOS COMPUT. BIOL., vol. 11, 2015, pages e1004400
JIANG, L. ET AL.: "Synthetic spike-in standards for RNA-seq experiments", GENOME RES., vol. 21, 2011, pages 1543 - 1551, XP055152443, DOI: doi:10.1101/gr.121095.111
KESELER, I.M. ET AL.: "The EcoCyc database: reflecting new knowledge about Escherichia coli K-12", NUCLEIC ACIDS RES., vol. 45, 2017, pages D543 - D550
KURATA, H. ET AL.: "Module-based analysis of robustness tradeoffs in the heat shock response system", PLOS COMPUT. BIOL., vol. 2, 2006, pages e59
KURLAND, C.G.; DONG, H.: "Bacterial growth inhibition by overproduction of protein", MOL. MICROBIOL., vol. 21, 1996, pages 1 - 4
LOHMAN, B.K.; WEBER, J.N.; BOLNICK, D.I.: "Evaluation of TagSeq, a reliable low-cost alternative for RNAseq", MOL. ECOL. RESOUR., vol. 16, 2016, pages 1315 - 1321
LOVE, M.I.; HUBER, W.; ANDERS, S.: "Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2", GENOME BIOL., vol. 15, 2014, pages 550, XP021210395, DOI: doi:10.1186/s13059-014-0550-8
LYNCH, M.; G. K. MARINOV: "The bioenergetic costs of a gene", PROC. NATL. ACAD. SCI. USA, vol. 112, 2015, pages 15690 - 15695
LYNCH, M.; MARINOV, G.K.: "The bioenergetic costs of a gene", PROC. NATL. ACAD. SCI. USA, vol. 112, 2015, pages 15690 - 15695
MOSER, F. ET AL.: "Genetic circuit performance under conditions relevant for industrial bioreactors", ACS SYNTH. BIOL., vol. 1, 2012, pages 555 - 564
MYERS, C.J. ET AL.: "A standard-enabled workflow for synthetic biology", BIOCHEM. SOC. TRANS., vol. 45, 2017, pages 793 - 803
NAKAHIGASHI, K.; YANAGI, H.; YURA, T.: "Regulatory conservation and divergence of 32 homologs from Pseudomonas aeruginosa, and Agrobacterium tumefaciens", MICROBIOLOGY, vol. 180, 1998, pages 2402 - 2408
NIELSEN, A.A.K. ET AL.: "Genetic circuit design automation", SCIENCE, vol. 352, 2016, pages aac7341, XP055469458, DOI: doi:10.1126/science.aac7341
NONAKA, G.; BLANKSCHIEN, M.; HERMAN, C.; GROSS, C.A.; RHODIUS, V.A.: "Regulon and promoter analysis of the E. coli heat-shock factor, D32, reveals a multifaceted cellular response to heat stress", GENES DEV., vol. 20, 2006, pages 1776 - 1789
PASINI, M. ET AL.: "Using promoter libraries to reduce metabolic burden due to plasmid-encoded proteins in recombinant Escherichia coli", N. BIOTECHNOL., vol. 33, 2016, pages 78 - 90
QIAN, Y.; HUANG, H.-H.; JIMENEZ, J.I.; DEL VECCHIO, D.: "Resource competition shapes the response of genetic circuits", ACS SYNTH. BIOL., vol. 6, 2017, pages 1263 - 1272
SEGALL-SHAPIRO, T.H.; MEYER, A.J.; ELLINGTON, A.D.; SONTAG, E.D.; VOIGT, C.A.A.: "A resource allocator' for transcription based on a highly fragmented T7 RNA polymerase", MOL. SYST. BIOL., vol. 10, 2014, pages 742
SHACHRAI, I.; ZASLAVER, A.; ALON, U.; DEKEL, E.: "Cost of unneeded proteins in E. coli is reduced after several generations in exponential growth", MOL. CELL, vol. 38, 2010, pages 758 - 767
SLEIGHT, S.C.; SAURO, H.M.: "Visualization of evolutionary stability dynamics and competitive fitness of Escherichia coli engineered with randomized multigene circuits", ACS SYNTH. BIOL., vol. 2, 2013, pages 519 - 528
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ZHANG, X. ET AL.: "Heat-shock response transcriptional program enables high-yield and high-quality recombinant protein production in Escherichia coli", ACS CHEM. BIOL., vol. 9, 2014, pages 1945 - 1949

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Owner name: IMPERIAL COLLEGE OF SCIENCE, TECHNOLOGY AND MEDICI

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AT Applications terminated before publication under section 16(1)