GB2015875A - Solid oral pharmaceutical product with increased efficacy and predetermined steady state of solubility - Google Patents
Solid oral pharmaceutical product with increased efficacy and predetermined steady state of solubilityInfo
- Publication number
- GB2015875A GB2015875A GB7905298A GB7905298A GB2015875A GB 2015875 A GB2015875 A GB 2015875A GB 7905298 A GB7905298 A GB 7905298A GB 7905298 A GB7905298 A GB 7905298A GB 2015875 A GB2015875 A GB 2015875A
- Authority
- GB
- United Kingdom
- Prior art keywords
- granules
- solid
- active ingredient
- oral pharmaceutical
- solid oral
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4866—Organic macromolecular compounds
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Inorganic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
A solid oral pharmaceutical preparation with protracted release of the active ingredient consists of discrete solid granules containing the active ingredient soluble in the stomach and auxiliary agents and of an equally solid external phase surrounding the said granules, whereby the granules forming the internal phase consist of granules prepared from a powder mixture which contains as active ingredient, or in addition to it a pharmaceutically acceptable basic bismuth salt, particularly bismuth subnitrate /basic bismuth nitrate/or bismuth subcarbonate and auxiliary materials prepared with an aqueous emulsion containing a hydrophobic component and hydrophylic emulsifiers, and the external phase contains a solid, dry, amphoteric gel forming substance preferably tragacanth in an amount of 1-50 per cent w/w related to the total weight of the preparation in admixture with auxiliary agents.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
HUIO001247 | 1978-02-24 |
Publications (2)
Publication Number | Publication Date |
---|---|
GB2015875A true GB2015875A (en) | 1979-09-19 |
GB2015875B GB2015875B (en) | 1982-10-20 |
Family
ID=10997585
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB7905298A Expired GB2015875B (en) | 1978-02-24 | 1979-02-14 | Solid oral pharaceutical product with increased efficacy and predetermined steady state of solubility |
Country Status (1)
Country | Link |
---|---|
GB (1) | GB2015875B (en) |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB2126086A (en) * | 1982-08-24 | 1984-03-21 | Cilag Ag | Medicated suppository containing gel-forming and gel-dispersing agents |
US4938967A (en) * | 1986-09-18 | 1990-07-03 | London School Of Pharmacy Innovations Ltd. | Pharmaceutical formulations |
EP0455475A2 (en) * | 1990-05-03 | 1991-11-06 | Reckitt And Colman Products Limited | Use of triclosan in the treatment of diseases of the gastrointestinal tract |
-
1979
- 1979-02-14 GB GB7905298A patent/GB2015875B/en not_active Expired
Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB2126086A (en) * | 1982-08-24 | 1984-03-21 | Cilag Ag | Medicated suppository containing gel-forming and gel-dispersing agents |
US4938967A (en) * | 1986-09-18 | 1990-07-03 | London School Of Pharmacy Innovations Ltd. | Pharmaceutical formulations |
EP0455475A2 (en) * | 1990-05-03 | 1991-11-06 | Reckitt And Colman Products Limited | Use of triclosan in the treatment of diseases of the gastrointestinal tract |
EP0455475A3 (en) * | 1990-05-03 | 1992-02-26 | Reckitt And Colman Products Limited | Use of triclosan in the treatment of diseases of the gastrointestinal tract |
US5286492A (en) * | 1990-05-03 | 1994-02-15 | Reckitt & Colman Products Limited | Method of treatment of Heliobacter pylori infections with triclosan |
Also Published As
Publication number | Publication date |
---|---|
GB2015875B (en) | 1982-10-20 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PCNP | Patent ceased through non-payment of renewal fee |