GB2015875A - Solid oral pharmaceutical product with increased efficacy and predetermined steady state of solubility - Google Patents

Solid oral pharmaceutical product with increased efficacy and predetermined steady state of solubility

Info

Publication number
GB2015875A
GB2015875A GB7905298A GB7905298A GB2015875A GB 2015875 A GB2015875 A GB 2015875A GB 7905298 A GB7905298 A GB 7905298A GB 7905298 A GB7905298 A GB 7905298A GB 2015875 A GB2015875 A GB 2015875A
Authority
GB
United Kingdom
Prior art keywords
granules
solid
active ingredient
oral pharmaceutical
solid oral
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
GB7905298A
Other versions
GB2015875B (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
NOVEX FOREIGN TRADE CO Ltd
Original Assignee
NOVEX FOREIGN TRADE CO Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by NOVEX FOREIGN TRADE CO Ltd filed Critical NOVEX FOREIGN TRADE CO Ltd
Publication of GB2015875A publication Critical patent/GB2015875A/en
Application granted granted Critical
Publication of GB2015875B publication Critical patent/GB2015875B/en
Expired legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/24Heavy metals; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2072Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841Filling excipients; Inactive ingredients
    • A61K9/4866Organic macromolecular compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Inorganic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

A solid oral pharmaceutical preparation with protracted release of the active ingredient consists of discrete solid granules containing the active ingredient soluble in the stomach and auxiliary agents and of an equally solid external phase surrounding the said granules, whereby the granules forming the internal phase consist of granules prepared from a powder mixture which contains as active ingredient, or in addition to it a pharmaceutically acceptable basic bismuth salt, particularly bismuth subnitrate /basic bismuth nitrate/or bismuth subcarbonate and auxiliary materials prepared with an aqueous emulsion containing a hydrophobic component and hydrophylic emulsifiers, and the external phase contains a solid, dry, amphoteric gel forming substance preferably tragacanth in an amount of 1-50 per cent w/w related to the total weight of the preparation in admixture with auxiliary agents.
GB7905298A 1978-02-24 1979-02-14 Solid oral pharaceutical product with increased efficacy and predetermined steady state of solubility Expired GB2015875B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HUIO001247 1978-02-24

Publications (2)

Publication Number Publication Date
GB2015875A true GB2015875A (en) 1979-09-19
GB2015875B GB2015875B (en) 1982-10-20

Family

ID=10997585

Family Applications (1)

Application Number Title Priority Date Filing Date
GB7905298A Expired GB2015875B (en) 1978-02-24 1979-02-14 Solid oral pharaceutical product with increased efficacy and predetermined steady state of solubility

Country Status (1)

Country Link
GB (1) GB2015875B (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2126086A (en) * 1982-08-24 1984-03-21 Cilag Ag Medicated suppository containing gel-forming and gel-dispersing agents
US4938967A (en) * 1986-09-18 1990-07-03 London School Of Pharmacy Innovations Ltd. Pharmaceutical formulations
EP0455475A2 (en) * 1990-05-03 1991-11-06 Reckitt And Colman Products Limited Use of triclosan in the treatment of diseases of the gastrointestinal tract

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2126086A (en) * 1982-08-24 1984-03-21 Cilag Ag Medicated suppository containing gel-forming and gel-dispersing agents
US4938967A (en) * 1986-09-18 1990-07-03 London School Of Pharmacy Innovations Ltd. Pharmaceutical formulations
EP0455475A2 (en) * 1990-05-03 1991-11-06 Reckitt And Colman Products Limited Use of triclosan in the treatment of diseases of the gastrointestinal tract
EP0455475A3 (en) * 1990-05-03 1992-02-26 Reckitt And Colman Products Limited Use of triclosan in the treatment of diseases of the gastrointestinal tract
US5286492A (en) * 1990-05-03 1994-02-15 Reckitt & Colman Products Limited Method of treatment of Heliobacter pylori infections with triclosan

Also Published As

Publication number Publication date
GB2015875B (en) 1982-10-20

Similar Documents

Publication Publication Date Title
HUT67634A (en) Herbicides containing sulfonamides as actives ingredient and process for preparation of the active ingredients
PT74703A (en) Process for the preparation of pharmaceutical compositions for topical use which are penetrable through the skin and contain as an active ingredient amongst others (e)-n-methyl-6,6-dimethyl-n-(naphtylmethyl)-hept-2-en-4-inyl-1-amine
GB2220949B (en) Aerosol composition comprising nitroglycerin as active ingredient
IL57796A0 (en) Pharmaceutical compositions having retarded release of the active substance
HU892559D0 (en) Process for the preparation of transdermal pharmaceutical composition suitable for systemic administration, containing deprenyl as active ingredient
JPS5323965A (en) 3*44dimethyll22hydroxyy55oxoo2*55dihydropyrrole derivative* its preparation and combating agent against harmful animals or plants containing same as acitive ingredient
IL58697A0 (en) Analgesic pharmaceutical compositions in the form of effervescent powders comprising metoclopramide
KR920702217A (en) Malaria Therapeutic Composition
EP0009688A3 (en) Medicated animal food based on liver powder, process for its preparation and its use in combating animal diseases
SE8207398D0 (en) AEROSOL ANTIPERSPIRANT COMPOSITION
IE891919L (en) Pharmaceutical dosage form for the medication of fish
JPS5321163A (en) Novel azolyllcarboxylic acid derivative* its preparation and fungicidal composition containing same as active ingredient
DE2966411D1 (en) Imidazolylvinylethers, their preparation and application as active agent in pharmaceutical and biocidal compositions
HUP9900365A3 (en) N-aryl-1,2,4-triazolin-5-on derivatives, preparation and use thereof, insecticide, arachnicide and nematocide compositions containing these compounds as active ingredients
GB2015875A (en) Solid oral pharmaceutical product with increased efficacy and predetermined steady state of solubility
PT76303B (en) Process for the preparation of pesticidal compositions containing the active substance in a aqueous vehicle
NL7705855A (en) PROCEDURE FOR THE PREPARATION OF PHARMACOLOGICALLY ACTIVE SUBSTITUATED BENZAMIDES AND PHARMACEUTICAL PREPARATIONS CONTAINING THESE COMPOUNDS.
IL92779A0 (en) Stable emulsion formulations of water-insoluble organic pesticides,their use and preparation
FI962056A0 (en) Novel pharmaceutical composition for the preparation of a stable powder containing an active ingredient comprising a combination of acetylsalicylic acid and metoclopramide
JPS5321164A (en) Novel 11azolyll44hydroxyybutane derivative* its preparation and fungicidal composition containing same as active ingredient
NZ190462A (en) Pharmaceutical formulation containing prostacyclin 15-methyl prostacyclin 16,16-dimethylprostacyclin or a salt thereof
DE2961994D1 (en) Ethene-azole derivatives, process for their preparation, fungicidal compositions and process for their preparation, use of the azole derivatives in combating fungi and process for combating fungi
HUT54289A (en) Fungicidal compositions comprising guanidine derivatives as active ingredient and process for producing the active ingredients
JPS57188520A (en) Antihyperkalemia
JPS5573646A (en) N*nndisubstituted aniline derivative*its manufacture and noxious organism killing agent containing it as active ingredient

Legal Events

Date Code Title Description
PCNP Patent ceased through non-payment of renewal fee