GB201516972D0 - LRP5 as epigenetic marker for the identification of immune cells, in particular B-cells - Google Patents

LRP5 as epigenetic marker for the identification of immune cells, in particular B-cells

Info

Publication number
GB201516972D0
GB201516972D0 GBGB1516972.5A GB201516972A GB201516972D0 GB 201516972 D0 GB201516972 D0 GB 201516972D0 GB 201516972 A GB201516972 A GB 201516972A GB 201516972 D0 GB201516972 D0 GB 201516972D0
Authority
GB
United Kingdom
Prior art keywords
cells
lrp5
identification
epigenetic marker
immune cells
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
GBGB1516972.5A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Precision for Medicine GmbH
Original Assignee
Epiontis GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Epiontis GmbH filed Critical Epiontis GmbH
Priority to GBGB1516972.5A priority Critical patent/GB201516972D0/en
Publication of GB201516972D0 publication Critical patent/GB201516972D0/en
Priority to CA2999611A priority patent/CA2999611C/en
Priority to EP16770025.1A priority patent/EP3353318B1/en
Priority to CN201680052685.1A priority patent/CN108026578A/zh
Priority to JP2018515528A priority patent/JP2018529345A/ja
Priority to US15/752,072 priority patent/US11643687B2/en
Priority to HK18116376.0A priority patent/HK1257122A1/zh
Priority to PCT/EP2016/072579 priority patent/WO2017050916A1/en
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6881—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for tissue or cell typing, e.g. human leukocyte antigen [HLA] probes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/154—Methylation markers

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Analytical Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
GBGB1516972.5A 2015-09-25 2015-09-25 LRP5 as epigenetic marker for the identification of immune cells, in particular B-cells Ceased GB201516972D0 (en)

Priority Applications (8)

Application Number Priority Date Filing Date Title
GBGB1516972.5A GB201516972D0 (en) 2015-09-25 2015-09-25 LRP5 as epigenetic marker for the identification of immune cells, in particular B-cells
CA2999611A CA2999611C (en) 2015-09-25 2016-09-22 Lrp5 as epigenetic marker for the identification of immune cells, in particular b-cells
EP16770025.1A EP3353318B1 (en) 2015-09-25 2016-09-22 Lrp5 as epigenetic marker for the identification of immune cells, in particular b-cells
CN201680052685.1A CN108026578A (zh) 2015-09-25 2016-09-22 Lrp5作为用于鉴定免疫细胞特别是b细胞的表观遗传标志物
JP2018515528A JP2018529345A (ja) 2015-09-25 2016-09-22 免疫細胞、特にb細胞の同定のためのエピジェネティックマーカーとしてのlrp5
US15/752,072 US11643687B2 (en) 2015-09-25 2016-09-22 LRP5 as epigenetic marker for the identification of immune cells, in particular B-cells
HK18116376.0A HK1257122A1 (zh) 2015-09-25 2016-09-22 Lrp5作为用於鉴定免疫细胞特别是b细胞的表观遗传标志物
PCT/EP2016/072579 WO2017050916A1 (en) 2015-09-25 2016-09-22 Lrp5 as epigenetic marker for the identification of immune cells, in particular b-cells

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB1516972.5A GB201516972D0 (en) 2015-09-25 2015-09-25 LRP5 as epigenetic marker for the identification of immune cells, in particular B-cells

Publications (1)

Publication Number Publication Date
GB201516972D0 true GB201516972D0 (en) 2015-11-11

Family

ID=54544102

Family Applications (1)

Application Number Title Priority Date Filing Date
GBGB1516972.5A Ceased GB201516972D0 (en) 2015-09-25 2015-09-25 LRP5 as epigenetic marker for the identification of immune cells, in particular B-cells

Country Status (7)

Country Link
US (1) US11643687B2 (OSRAM)
EP (1) EP3353318B1 (OSRAM)
JP (1) JP2018529345A (OSRAM)
CN (1) CN108026578A (OSRAM)
GB (1) GB201516972D0 (OSRAM)
HK (1) HK1257122A1 (OSRAM)
WO (1) WO2017050916A1 (OSRAM)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20200340057A1 (en) * 2017-07-13 2020-10-29 Yissum Research Development Company Of The Hebrew University Of Jerusalem Dna targets as tissue-specific methylation markers
CN111918964B (zh) * 2018-03-26 2025-05-30 原启生物科技(上海)有限责任公司 促进免疫细胞增殖的方法
DE102018112644B4 (de) * 2018-05-25 2020-06-10 Epiontis Gmbh CXCR3 als epigenetischer Marker zur Identifizierung von inflammatorischen Immunzellen, insbesondere CD8+ Gedächnis-T-Zellen
DE102018116353B4 (de) * 2018-07-05 2020-06-10 Epiontis Gmbh Verfahren zum Nachweis und zur Zählung epigenetischer Immunzellen in humanen Blutproben für Immundiagnostik und Neugeborenen-Screening
DE102020108560B4 (de) * 2020-03-27 2022-03-03 Precision For Medicine Gmbh CBX6 als epigenetischer Marker für die Identifizierung von Immunzellen, insbesondere Gedächtnis-B-Zellen
CN119372296B (zh) * 2024-12-24 2025-06-13 北京致谱医学检验实验室有限公司 基于基因甲基化检测实现人b淋巴细胞计数的试剂盒

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1285002B1 (en) * 2000-05-26 2007-07-18 Oscient Pharmaceuticals Corporation Regulating lipid levels via the zmax1 or hbm gene
US20070243161A1 (en) * 2006-02-28 2007-10-18 Sven Olek Epigenetic modification of the loci for CAMTA1 and/or FOXP3 as a marker for cancer treatment
SG185942A1 (en) * 2007-11-02 2012-12-28 Agency Science Tech & Res Methods and compounds for preventing and treating a tumour
US20110104695A1 (en) * 2009-11-05 2011-05-05 Epigenomics Ag Methods of predicting therapeutic efficacy of cancer therapy
JP6010037B2 (ja) * 2010-10-08 2016-10-19 エピオンティス ゲーエムベーハー 腫瘍浸潤全tリンパ球の分析に基づいて、がん患者の生存指標を測定する方法
WO2013033627A2 (en) * 2011-09-01 2013-03-07 The Regents Of The University Of California Diagnosis and treatment of arthritis using epigenetics
PL3327141T3 (pl) * 2013-04-19 2020-07-27 Epiontis Gmbh Sposób określania ilościowego składu komórkowego w próbce biologicznej
KR20170013921A (ko) 2014-05-30 2017-02-07 로버트 필리버트 알콜 사용 및 금주에 대한 바이오마커로서의 dna 메틸화 상태

Also Published As

Publication number Publication date
EP3353318A1 (en) 2018-08-01
JP2018529345A (ja) 2018-10-11
US11643687B2 (en) 2023-05-09
EP3353318B1 (en) 2021-03-10
US20180216185A1 (en) 2018-08-02
WO2017050916A1 (en) 2017-03-30
CA2999611A1 (en) 2017-03-30
CN108026578A (zh) 2018-05-11
HK1257122A1 (zh) 2019-10-11

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Legal Events

Date Code Title Description
AT Applications terminated before publication under section 16(1)