GB2013673A - New Cephalosporin Synthesis - Google Patents

New Cephalosporin Synthesis

Info

Publication number
GB2013673A
GB2013673A GB7903347A GB7903347A GB2013673A GB 2013673 A GB2013673 A GB 2013673A GB 7903347 A GB7903347 A GB 7903347A GB 7903347 A GB7903347 A GB 7903347A GB 2013673 A GB2013673 A GB 2013673A
Authority
GB
United Kingdom
Prior art keywords
new cephalosporin
formula
image
cephalosporin synthesis
synthesis
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
GB7903347A
Other versions
GB2013673B (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Lilly Industries Ltd
Original Assignee
Lilly Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Industries Ltd filed Critical Lilly Industries Ltd
Priority to GB7903347A priority Critical patent/GB2013673B/en
Publication of GB2013673A publication Critical patent/GB2013673A/en
Application granted granted Critical
Publication of GB2013673B publication Critical patent/GB2013673B/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/02—Preparation
    • C07D501/04—Preparation from compounds already containing the ring or condensed ring systems, e.g. by dehydrogenation of the ring, by introduction, elimination or modification of substituents
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Abstract

A process for the preparation of 3- exomethylene cepham sulphoxide of formula (I): <IMAGE> wherein R and R<1> are independently hydrogen or acyl and where R<2> is hydrogen or an ester protecting group, which process comprises treating a compound of formula (II): <IMAGE> where R, R<1> and R<2> are as previously defined and where X is bromine or iodine, with a mercury salt containing a non-nucleophilic anion.
GB7903347A 1977-12-24 1979-01-31 Cephalosporin syntheis Expired GB2013673B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
GB7903347A GB2013673B (en) 1977-12-24 1979-01-31 Cephalosporin syntheis

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB5389777 1977-12-24
GB7903347A GB2013673B (en) 1977-12-24 1979-01-31 Cephalosporin syntheis

Publications (2)

Publication Number Publication Date
GB2013673A true GB2013673A (en) 1979-08-15
GB2013673B GB2013673B (en) 1982-06-03

Family

ID=26267363

Family Applications (1)

Application Number Title Priority Date Filing Date
GB7903347A Expired GB2013673B (en) 1977-12-24 1979-01-31 Cephalosporin syntheis

Country Status (1)

Country Link
GB (1) GB2013673B (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0351121A3 (en) * 1988-07-12 1991-09-18 Jack Edward Baldwin Process for producing exomethylene cepham compounds

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0351121A3 (en) * 1988-07-12 1991-09-18 Jack Edward Baldwin Process for producing exomethylene cepham compounds
JP2735297B2 (en) 1988-07-12 1998-04-02 エドワード ボルドウィン ジャック Production of intermediates

Also Published As

Publication number Publication date
GB2013673B (en) 1982-06-03

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Legal Events

Date Code Title Description
PE20 Patent expired after termination of 20 years

Effective date: 19990130