GB2013198A - Preparation of the pivaloyloxymethyl ester of Cephalexin - Google Patents

Preparation of the pivaloyloxymethyl ester of Cephalexin

Info

Publication number
GB2013198A
GB2013198A GB7902862A GB7902862A GB2013198A GB 2013198 A GB2013198 A GB 2013198A GB 7902862 A GB7902862 A GB 7902862A GB 7902862 A GB7902862 A GB 7902862A GB 2013198 A GB2013198 A GB 2013198A
Authority
GB
United Kingdom
Prior art keywords
cephalexin
preparation
pivaloyloxymethyl ester
pivaloyloxymethyl
penicillin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
GB7902862A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sigma Tau Industrie Farmaceutiche Riunite SpA
Original Assignee
Sigma Tau Industrie Farmaceutiche Riunite SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sigma Tau Industrie Farmaceutiche Riunite SpA filed Critical Sigma Tau Industrie Farmaceutiche Riunite SpA
Publication of GB2013198A publication Critical patent/GB2013198A/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/22—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with radicals containing only hydrogen and carbon atoms, attached in position 3

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)

Abstract

A method for the preparation of the pivaloyloxymethyl ester of cephalexin or pivaloyloxymethyl 7- [D(-) alpha -amino (phenylacetamido)]-3- methylcef-3-em-4-carboxylate of formula (I) and its optically active and non-active pharmacologically acceptable salts in which the starting compound is either penicillin G or penicillin V, as such or as a salt.
GB7902862A 1978-01-27 1979-01-26 Preparation of the pivaloyloxymethyl ester of Cephalexin Withdrawn GB2013198A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT47812/78A IT1181586B (en) 1978-01-27 1978-01-27 METHOD OF PREPARATION OF PIVALOYLOXYMETHYL ESTER OF CEPHALEXIN

Publications (1)

Publication Number Publication Date
GB2013198A true GB2013198A (en) 1979-08-08

Family

ID=11262670

Family Applications (1)

Application Number Title Priority Date Filing Date
GB7902862A Withdrawn GB2013198A (en) 1978-01-27 1979-01-26 Preparation of the pivaloyloxymethyl ester of Cephalexin

Country Status (15)

Country Link
JP (1) JPS54112888A (en)
AU (1) AU4369279A (en)
BE (1) BE873646A (en)
DE (1) DE2902543A1 (en)
DK (1) DK33979A (en)
ES (1) ES477209A1 (en)
FR (1) FR2415638A1 (en)
GB (1) GB2013198A (en)
GR (1) GR65655B (en)
IT (1) IT1181586B (en)
LU (1) LU80834A1 (en)
NL (1) NL7900367A (en)
NO (1) NO790259L (en)
PT (1) PT69139A (en)
SE (1) SE7900716L (en)

Also Published As

Publication number Publication date
NO790259L (en) 1979-07-30
DK33979A (en) 1979-07-28
DE2902543A1 (en) 1979-08-02
SE7900716L (en) 1979-07-28
BE873646A (en) 1979-05-16
IT7847812A0 (en) 1978-01-27
IT1181586B (en) 1987-09-30
ES477209A1 (en) 1980-05-16
NL7900367A (en) 1979-07-31
PT69139A (en) 1979-02-01
GR65655B (en) 1980-10-16
JPS54112888A (en) 1979-09-04
LU80834A1 (en) 1979-06-05
FR2415638A1 (en) 1979-08-24
AU4369279A (en) 1979-08-02

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Legal Events

Date Code Title Description
WAP Application withdrawn, taken to be withdrawn or refused ** after publication under section 16(1)