GB2013194A - Carbamates of Monolysergols (8beta-hydroxyethylergolines) - Google Patents
Carbamates of Monolysergols (8beta-hydroxyethylergolines)Info
- Publication number
- GB2013194A GB2013194A GB7902242A GB7902242A GB2013194A GB 2013194 A GB2013194 A GB 2013194A GB 7902242 A GB7902242 A GB 7902242A GB 7902242 A GB7902242 A GB 7902242A GB 2013194 A GB2013194 A GB 2013194A
- Authority
- GB
- United Kingdom
- Prior art keywords
- alkyl
- hydrogen
- monolysergols
- hydroxyethylergolines
- 8beta
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
- C07D457/02—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with hydrocarbon or substituted hydrocarbon radicals, attached in position 8
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
Novel ergoline derivatives having antiasthmatic, antihypertensive and antidepressant activity are disclosed having the general formula (I> <IMAGE> wherein R1 is hydrogen or C1-4 alkyl radical; Z is hydrogen, bromine, S-RIV (in which RIV is C1-4 alkyl; RII is equal to RIII and is an C1-6 alkyl or RII together with RIII is -(CH2)n, where n is from 2 to 7, or is -(CH2)n-A-(CH2)n, where n is from 2 to 5 and A=0 or where RV is hydrogen, C1-4 alkyl, or phenyl; and x@y is <IMAGE> D-2-Methyl-1,6-dimethyl- 8 beta (morpholinocarbonyloxy) ergoline is disclosed.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB7902242A GB2013194B (en) | 1978-01-26 | 1979-01-22 | Carbamates of monolysergols (8 beta hydroxy ethylergolines) |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB326278 | 1978-01-26 | ||
GB7902242A GB2013194B (en) | 1978-01-26 | 1979-01-22 | Carbamates of monolysergols (8 beta hydroxy ethylergolines) |
Publications (2)
Publication Number | Publication Date |
---|---|
GB2013194A true GB2013194A (en) | 1979-08-08 |
GB2013194B GB2013194B (en) | 1982-09-22 |
Family
ID=26238174
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB7902242A Expired GB2013194B (en) | 1978-01-26 | 1979-01-22 | Carbamates of monolysergols (8 beta hydroxy ethylergolines) |
Country Status (1)
Country | Link |
---|---|
GB (1) | GB2013194B (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4739061A (en) * | 1985-07-11 | 1988-04-19 | Rhone-Poulenc Sante | Process for preparing n-methyl derivatives of methyl dihydrolysergate and methyl methoxylumilysergate |
-
1979
- 1979-01-22 GB GB7902242A patent/GB2013194B/en not_active Expired
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4739061A (en) * | 1985-07-11 | 1988-04-19 | Rhone-Poulenc Sante | Process for preparing n-methyl derivatives of methyl dihydrolysergate and methyl methoxylumilysergate |
Also Published As
Publication number | Publication date |
---|---|
GB2013194B (en) | 1982-09-22 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PCNP | Patent ceased through non-payment of renewal fee |