GB2013194A - Carbamates of Monolysergols (8beta-hydroxyethylergolines) - Google Patents

Carbamates of Monolysergols (8beta-hydroxyethylergolines)

Info

Publication number
GB2013194A
GB2013194A GB7902242A GB7902242A GB2013194A GB 2013194 A GB2013194 A GB 2013194A GB 7902242 A GB7902242 A GB 7902242A GB 7902242 A GB7902242 A GB 7902242A GB 2013194 A GB2013194 A GB 2013194A
Authority
GB
United Kingdom
Prior art keywords
alkyl
hydrogen
monolysergols
hydroxyethylergolines
8beta
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
GB7902242A
Other versions
GB2013194B (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SIMES
Original Assignee
SIMES
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SIMES filed Critical SIMES
Priority to GB7902242A priority Critical patent/GB2013194B/en
Publication of GB2013194A publication Critical patent/GB2013194A/en
Application granted granted Critical
Publication of GB2013194B publication Critical patent/GB2013194B/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D457/00Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
    • C07D457/02Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with hydrocarbon or substituted hydrocarbon radicals, attached in position 8

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

Novel ergoline derivatives having antiasthmatic, antihypertensive and antidepressant activity are disclosed having the general formula (I> <IMAGE> wherein R1 is hydrogen or C1-4 alkyl radical; Z is hydrogen, bromine, S-RIV (in which RIV is C1-4 alkyl; RII is equal to RIII and is an C1-6 alkyl or RII together with RIII is -(CH2)n, where n is from 2 to 7, or is -(CH2)n-A-(CH2)n, where n is from 2 to 5 and A=0 or where RV is hydrogen, C1-4 alkyl, or phenyl; and x@y is <IMAGE> D-2-Methyl-1,6-dimethyl- 8 beta (morpholinocarbonyloxy) ergoline is disclosed.
GB7902242A 1978-01-26 1979-01-22 Carbamates of monolysergols (8 beta hydroxy ethylergolines) Expired GB2013194B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
GB7902242A GB2013194B (en) 1978-01-26 1979-01-22 Carbamates of monolysergols (8 beta hydroxy ethylergolines)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB326278 1978-01-26
GB7902242A GB2013194B (en) 1978-01-26 1979-01-22 Carbamates of monolysergols (8 beta hydroxy ethylergolines)

Publications (2)

Publication Number Publication Date
GB2013194A true GB2013194A (en) 1979-08-08
GB2013194B GB2013194B (en) 1982-09-22

Family

ID=26238174

Family Applications (1)

Application Number Title Priority Date Filing Date
GB7902242A Expired GB2013194B (en) 1978-01-26 1979-01-22 Carbamates of monolysergols (8 beta hydroxy ethylergolines)

Country Status (1)

Country Link
GB (1) GB2013194B (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4739061A (en) * 1985-07-11 1988-04-19 Rhone-Poulenc Sante Process for preparing n-methyl derivatives of methyl dihydrolysergate and methyl methoxylumilysergate

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4739061A (en) * 1985-07-11 1988-04-19 Rhone-Poulenc Sante Process for preparing n-methyl derivatives of methyl dihydrolysergate and methyl methoxylumilysergate

Also Published As

Publication number Publication date
GB2013194B (en) 1982-09-22

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Legal Events

Date Code Title Description
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