GB2012162A - Injectable compositions containing a source of manganous ions for use in the immunotherapy of neoplastic disease - Google Patents

Injectable compositions containing a source of manganous ions for use in the immunotherapy of neoplastic disease

Info

Publication number
GB2012162A
GB2012162A GB7843897A GB7843897A GB2012162A GB 2012162 A GB2012162 A GB 2012162A GB 7843897 A GB7843897 A GB 7843897A GB 7843897 A GB7843897 A GB 7843897A GB 2012162 A GB2012162 A GB 2012162A
Authority
GB
United Kingdom
Prior art keywords
source
neoplastic disease
immunotherapy
compositions containing
injectable compositions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
GB7843897A
Other versions
GB2012162B (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to GB7843897A priority Critical patent/GB2012162B/en
Publication of GB2012162A publication Critical patent/GB2012162A/en
Application granted granted Critical
Publication of GB2012162B publication Critical patent/GB2012162B/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H23/00—Compounds containing boron, silicon, or a metal, e.g. chelates, vitamin B12
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/32—Manganese; Compounds thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids

Abstract

An injectable composition for treating neoplastic disease (cancer) by in situ injection of the cancer comprises a source of manganous ions in an injectable medium. Optional further components of the composition are macromolecular polysaccharides and zinc, calcium, manganese or aluminium triphosphate gels. Suitable sources of Mn<2+> are manganous chloride, carbonate, hydroxide, stearate, guanylate, and hydrogen phosphate gel. The compositions have immunostimulant activity to cause rejection of neoplastic cells.
GB7843897A 1977-11-24 1978-11-09 Composition for use in the immunotherapy of neoplastic disease Expired GB2012162B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
GB7843897A GB2012162B (en) 1977-11-24 1978-11-09 Composition for use in the immunotherapy of neoplastic disease

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB4890977 1977-11-24
GB7843897A GB2012162B (en) 1977-11-24 1978-11-09 Composition for use in the immunotherapy of neoplastic disease

Publications (2)

Publication Number Publication Date
GB2012162A true GB2012162A (en) 1979-07-25
GB2012162B GB2012162B (en) 1982-08-11

Family

ID=26266353

Family Applications (1)

Application Number Title Priority Date Filing Date
GB7843897A Expired GB2012162B (en) 1977-11-24 1978-11-09 Composition for use in the immunotherapy of neoplastic disease

Country Status (1)

Country Link
GB (1) GB2012162B (en)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0052874A1 (en) * 1980-11-21 1982-06-02 Gerard Marx Method for synthesizing procoagulant factor VIII activity
US4910224A (en) * 1986-02-14 1990-03-20 Habib Nagy A Method of modifying the lipid structure and function of cell membranes and pharmaceutical compositions for use therein
EP0605908A2 (en) * 1992-12-17 1994-07-13 NanoSystems L.L.C. Water insoluble manganese particles as magnetic resonance, imaging contrast enhancement agents
WO2008001110A2 (en) * 2006-06-29 2008-01-03 Remedy Research Limited Manganese, zinc and selenium compositions, preparations and uses

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0052874A1 (en) * 1980-11-21 1982-06-02 Gerard Marx Method for synthesizing procoagulant factor VIII activity
US4910224A (en) * 1986-02-14 1990-03-20 Habib Nagy A Method of modifying the lipid structure and function of cell membranes and pharmaceutical compositions for use therein
EP0605908A2 (en) * 1992-12-17 1994-07-13 NanoSystems L.L.C. Water insoluble manganese particles as magnetic resonance, imaging contrast enhancement agents
EP0605908A3 (en) * 1992-12-17 1994-08-17 Sterling Winthrop Inc Water insoluble manganese particles as magnetic resonance, imaging contrast enhancement agents.
WO2008001110A2 (en) * 2006-06-29 2008-01-03 Remedy Research Limited Manganese, zinc and selenium compositions, preparations and uses
WO2008001110A3 (en) * 2006-06-29 2008-03-27 Remedy Res Ltd Manganese, zinc and selenium compositions, preparations and uses

Also Published As

Publication number Publication date
GB2012162B (en) 1982-08-11

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Legal Events

Date Code Title Description
PCNP Patent ceased through non-payment of renewal fee

Effective date: 19941109