GB2012068A - Analysis of blood to obtain numerical indication of blood sugar condition - Google Patents

Analysis of blood to obtain numerical indication of blood sugar condition

Info

Publication number
GB2012068A
GB2012068A GB7846811A GB7846811A GB2012068A GB 2012068 A GB2012068 A GB 2012068A GB 7846811 A GB7846811 A GB 7846811A GB 7846811 A GB7846811 A GB 7846811A GB 2012068 A GB2012068 A GB 2012068A
Authority
GB
United Kingdom
Prior art keywords
blood
sugar condition
blood sugar
analysis
numerical indication
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
GB7846811A
Other versions
GB2012068B (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Isolab Inc
Original Assignee
Isolab Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/856,724 external-priority patent/US4142857A/en
Priority claimed from US05/856,723 external-priority patent/US4142856A/en
Priority claimed from US05/856,722 external-priority patent/US4142855A/en
Priority claimed from US05/856,725 external-priority patent/US4142858A/en
Priority claimed from US05/932,647 external-priority patent/US4168147A/en
Application filed by Isolab Inc filed Critical Isolab Inc
Publication of GB2012068A publication Critical patent/GB2012068A/en
Application granted granted Critical
Publication of GB2012068B publication Critical patent/GB2012068B/en
Expired legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/96—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation using ion-exchange
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/66—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood sugars, e.g. galactose

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Diabetes (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

The analytical method, which is based on the relationship between the amount of certain haemoglobins in blood and the blood sugar condition, comprises eluting haemolysed blood through a column containing, as chromatography medium, particles of an ion-exchange resin (such as a methacrylic acid/divinyl benzene copolymer or a cellulose derivative), spectrometrically analysing the eluate so as to obtain a numerical value A corresponding to the haemoglobin-A1 content of the haemolysate and spectrometrically determining a numerical value B corresponding to the total of the haemoglobin components of the haemolysate, the ratio A:B giving a numerical indication of a blood sugar condition. The method is quick, simple, accurate and suitable for routine repetition.
GB7846811A 1977-12-02 1978-12-01 Analysis of blood to obtain a numerical indication of blood sugar condition Expired GB2012068B (en)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US85672177A 1977-12-02 1977-12-02
US05/856,724 US4142857A (en) 1977-12-02 1977-12-02 Method to determine a diagnostic indicator of blood sugar condition, and, a liquid chromatographic microcolumn therefor
US05/856,723 US4142856A (en) 1977-12-02 1977-12-02 Method to determine a diagnostic indicator of blood sugar condition, and, a liquid chromatographic microcolumn therefor
US05/856,722 US4142855A (en) 1977-12-02 1977-12-02 Method to determine a diagnostic indicator of blood sugar condition, and, a liquid chromatographic microcolumn therefor
US05/856,725 US4142858A (en) 1977-12-02 1977-12-02 Method to determine a diagnostic indicator of blood sugar condition, and, a liquid chromatographic microcolumn therefor
US05/932,647 US4168147A (en) 1977-12-02 1978-08-10 Method to determine a diagnostic indicator of blood sugar condition, and, a liquid chromatographic microcolumn therefor

Publications (2)

Publication Number Publication Date
GB2012068A true GB2012068A (en) 1979-07-18
GB2012068B GB2012068B (en) 1982-02-17

Family

ID=27560322

Family Applications (2)

Application Number Title Priority Date Filing Date
GB7846811A Expired GB2012068B (en) 1977-12-02 1978-12-01 Analysis of blood to obtain a numerical indication of blood sugar condition
GB7846813A Expired GB2011801B (en) 1977-12-02 1978-12-01 Microcolumn suitable for chromatography of red blood cell haemolysates

Family Applications After (1)

Application Number Title Priority Date Filing Date
GB7846813A Expired GB2011801B (en) 1977-12-02 1978-12-01 Microcolumn suitable for chromatography of red blood cell haemolysates

Country Status (3)

Country Link
CH (1) CH648128A5 (en)
DE (1) DE2851827C2 (en)
GB (2) GB2012068B (en)

Also Published As

Publication number Publication date
GB2011801B (en) 1982-01-13
DE2851827C2 (en) 1983-06-16
GB2011801A (en) 1979-07-18
DE2851827A1 (en) 1979-06-13
GB2012068B (en) 1982-02-17
CH648128A5 (en) 1985-02-28

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Legal Events

Date Code Title Description
PCNP Patent ceased through non-payment of renewal fee

Effective date: 19921201