GB201100404D0 - Combination of metformin and syrosingopine for the treatment of cancer and immunosuppression - Google Patents

Combination of metformin and syrosingopine for the treatment of cancer and immunosuppression

Info

Publication number
GB201100404D0
GB201100404D0 GBGB1100404.1A GB201100404A GB201100404D0 GB 201100404 D0 GB201100404 D0 GB 201100404D0 GB 201100404 A GB201100404 A GB 201100404A GB 201100404 D0 GB201100404 D0 GB 201100404D0
Authority
GB
United Kingdom
Prior art keywords
syrosingopine
metformin
immunosuppression
cancer
treatment
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
GBGB1100404.1A
Other versions
GB2487351A (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Universitaet Basel
Original Assignee
Universitaet Basel
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Universitaet Basel filed Critical Universitaet Basel
Priority to GB1100404.1A priority Critical patent/GB2487351A/en
Publication of GB201100404D0 publication Critical patent/GB201100404D0/en
Priority to AU2012206649A priority patent/AU2012206649A1/en
Priority to KR1020137016147A priority patent/KR20130142164A/en
Priority to EP12700325.9A priority patent/EP2663298A1/en
Priority to RU2013137380/14A priority patent/RU2602937C2/en
Priority to MX2013007835A priority patent/MX2013007835A/en
Priority to JP2013548805A priority patent/JP5940559B2/en
Priority to BR112013017499A priority patent/BR112013017499A2/en
Priority to CN201280005080.9A priority patent/CN103442705B/en
Priority to CA2824096A priority patent/CA2824096A1/en
Priority to PCT/EP2012/050216 priority patent/WO2012095379A1/en
Priority to US13/977,811 priority patent/US8993587B2/en
Publication of GB2487351A publication Critical patent/GB2487351A/en
Priority to US14/627,283 priority patent/US20150157623A1/en
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/475—Quinolines; Isoquinolines having an indole ring, e.g. yohimbine, reserpine, strychnine, vinblastine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Transplantation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
GB1100404.1A 2011-01-11 2011-01-11 Combination of syrosingopine and a biguanide Withdrawn GB2487351A (en)

Priority Applications (13)

Application Number Priority Date Filing Date Title
GB1100404.1A GB2487351A (en) 2011-01-11 2011-01-11 Combination of syrosingopine and a biguanide
US13/977,811 US8993587B2 (en) 2011-01-11 2012-01-09 Combination of syrosingopine and mitochondrial inhibitors for the treatment of cancer and immunosuppression
JP2013548805A JP5940559B2 (en) 2011-01-11 2012-01-09 Combination of syrosingopine and mitochondrial inhibitors for the treatment of cancer and immunosuppression
CN201280005080.9A CN103442705B (en) 2011-01-11 2012-01-09 Be used for the treatment of the combination of cancer and immunosuppressant syrosingopine and mitochondrial inhibitors
EP12700325.9A EP2663298A1 (en) 2011-01-11 2012-01-09 Combination of syrosingopine and mitochondrial inhibitors for the treatment of cancer and immunosuppression
RU2013137380/14A RU2602937C2 (en) 2011-01-11 2012-01-09 Combination of sirosingopin and mitochondrial inhibitors for treatment of cancer and for immunosuppression
MX2013007835A MX2013007835A (en) 2011-01-11 2012-01-09 Combination of syrosingopine and mitochondrial inhibitors for the treatment of cancer and immunosuppression.
AU2012206649A AU2012206649A1 (en) 2011-01-11 2012-01-09 Combination of syrosingopine and mitochondrial inhibitors for the treatment of cancer and immunosuppression
BR112013017499A BR112013017499A2 (en) 2011-01-11 2012-01-09 combination of sirosingopine and mitochondrial inhibitors for the treatment of cancer and immunosuppression
KR1020137016147A KR20130142164A (en) 2011-01-11 2012-01-09 Combination of syrosingopine and mitochondrial inhibitors for the treatment of cancer and immunosuppression
CA2824096A CA2824096A1 (en) 2011-01-11 2012-01-09 Combination of syrosingopine and mitochondrial inhibitors for the treatment of cancer and immunosuppression
PCT/EP2012/050216 WO2012095379A1 (en) 2011-01-11 2012-01-09 Combination of syrosingopine and mitochondrial inhibitors for the treatment of cancer and immunosuppression
US14/627,283 US20150157623A1 (en) 2011-01-11 2015-02-20 Combination of syrosingopine and mitochondrial inhibitors for the treatment of cancer and immunosuppression

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB1100404.1A GB2487351A (en) 2011-01-11 2011-01-11 Combination of syrosingopine and a biguanide

Publications (2)

Publication Number Publication Date
GB201100404D0 true GB201100404D0 (en) 2011-02-23
GB2487351A GB2487351A (en) 2012-07-25

Family

ID=43664065

Family Applications (1)

Application Number Title Priority Date Filing Date
GB1100404.1A Withdrawn GB2487351A (en) 2011-01-11 2011-01-11 Combination of syrosingopine and a biguanide

Country Status (1)

Country Link
GB (1) GB2487351A (en)

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009029206A1 (en) * 2007-08-24 2009-03-05 Wake Forest University Health Sciences Chemotherapeutic for inducing an msh2-dependent apoptotic pathway
CN101691344B (en) * 2009-10-26 2012-10-17 漆又毛 Metformin acidic double salt compound and preparation method

Also Published As

Publication number Publication date
GB2487351A (en) 2012-07-25

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Legal Events

Date Code Title Description
WAP Application withdrawn, taken to be withdrawn or refused ** after publication under section 16(1)