GB2008093A - 2,6-Methano-2H-1-Benzocins - Google Patents
2,6-Methano-2H-1-BenzocinsInfo
- Publication number
- GB2008093A GB2008093A GB7835758A GB7835758A GB2008093A GB 2008093 A GB2008093 A GB 2008093A GB 7835758 A GB7835758 A GB 7835758A GB 7835758 A GB7835758 A GB 7835758A GB 2008093 A GB2008093 A GB 2008093A
- Authority
- GB
- United Kingdom
- Prior art keywords
- formula
- image
- methano
- benzoxocins
- alkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/78—Ring systems having three or more relevant rings
- C07D311/80—Dibenzopyrans; Hydrogenated dibenzopyrans
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D313/00—Heterocyclic compounds containing rings of more than six members having one oxygen atom as the only ring hetero atom
- C07D313/16—Eight-membered rings
- C07D313/20—Eight-membered rings condensed with carbocyclic rings or ring systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pyrane Compounds (AREA)
Abstract
A process for preparing 5-isopropylidene-2,7- dihydroxy-9-substituted-2,6- methano-3,4,5,6- tetrahydro-2H-1-benzoxocins of the formula <IMAGE> in which R1 is C5-C10 alkyl, C5-C10 alkenyl, C5-C8 cycloalkyl, or C5-C8 cycloalkenyl; which process is characterized by reacting a 1-alkoxy-4-(1- hydroxy-1-methylethyl)-1, 4-cyclohexadiene of the formula <IMAGE> wherein R3 is C1-C4 alkyl, with a 5-substituted resorcinol of the formula <IMAGE> in an organic solvent in the presence of stannic chloride for from 1 to 15 minutes at a temperature from -40 DEG C. to ambient temperature. The benzoxocins prepared are useful intermediates in the production of dibenzo [b,d] pyran-9- ores which are anti-anxiety, analgesic and anti-depressant drugs.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US05/831,454 US4140701A (en) | 1976-07-06 | 1977-09-08 | 2,6-Methano-2H-1-benzoxocins |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| GB2008093A true GB2008093A (en) | 1979-05-31 |
| GB2008093B GB2008093B (en) | 1982-03-10 |
Family
ID=25259096
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB7835758A Expired GB2008093B (en) | 1977-09-08 | 1978-09-06 | 2,6-methano-2h-1-benzoxcins |
Country Status (25)
| Country | Link |
|---|---|
| JP (1) | JPS5448769A (en) |
| AT (1) | AT360987B (en) |
| AU (1) | AU517889B2 (en) |
| BE (1) | BE870194A (en) |
| BG (1) | BG30023A3 (en) |
| CA (1) | CA1095062A (en) |
| CS (1) | CS203015B2 (en) |
| DD (1) | DD137227A5 (en) |
| DE (1) | DE2838496A1 (en) |
| DK (1) | DK396078A (en) |
| ES (1) | ES473175A1 (en) |
| FR (1) | FR2402656A1 (en) |
| GB (1) | GB2008093B (en) |
| GR (1) | GR70022B (en) |
| HU (1) | HU179461B (en) |
| IL (1) | IL55490A (en) |
| IT (1) | IT1099496B (en) |
| NL (1) | NL7809137A (en) |
| NZ (1) | NZ188366A (en) |
| PL (1) | PL112630B1 (en) |
| PT (1) | PT68502A (en) |
| RO (1) | RO75487A (en) |
| SE (1) | SE7809389L (en) |
| YU (1) | YU208478A (en) |
| ZA (1) | ZA785059B (en) |
-
1978
- 1978-09-03 IL IL55490A patent/IL55490A/en unknown
- 1978-09-04 GR GR57159A patent/GR70022B/el unknown
- 1978-09-04 BG BG7840810A patent/BG30023A3/en unknown
- 1978-09-04 PT PT68502A patent/PT68502A/en unknown
- 1978-09-04 DE DE19782838496 patent/DE2838496A1/en not_active Withdrawn
- 1978-09-04 YU YU02084/78A patent/YU208478A/en unknown
- 1978-09-05 PL PL1978209418A patent/PL112630B1/en unknown
- 1978-09-05 CA CA310,599A patent/CA1095062A/en not_active Expired
- 1978-09-05 FR FR7825520A patent/FR2402656A1/en active Granted
- 1978-09-05 BE BE1009043A patent/BE870194A/en unknown
- 1978-09-05 AU AU39562/78A patent/AU517889B2/en not_active Expired
- 1978-09-05 AT AT642278A patent/AT360987B/en not_active IP Right Cessation
- 1978-09-05 JP JP10904278A patent/JPS5448769A/en active Pending
- 1978-09-05 RO RO7895112A patent/RO75487A/en unknown
- 1978-09-06 ZA ZA785059A patent/ZA785059B/en unknown
- 1978-09-06 GB GB7835758A patent/GB2008093B/en not_active Expired
- 1978-09-06 SE SE7809389A patent/SE7809389L/en unknown
- 1978-09-07 HU HU78EI810A patent/HU179461B/en unknown
- 1978-09-07 IT IT27434/78A patent/IT1099496B/en active
- 1978-09-07 ES ES473175A patent/ES473175A1/en not_active Expired
- 1978-09-07 NZ NZ188366A patent/NZ188366A/en unknown
- 1978-09-07 DK DK396078A patent/DK396078A/en unknown
- 1978-09-07 DD DD78207686A patent/DD137227A5/en unknown
- 1978-09-07 NL NL7809137A patent/NL7809137A/en not_active Application Discontinuation
- 1978-09-08 CS CS785823A patent/CS203015B2/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| BG30023A3 (en) | 1981-03-16 |
| CS203015B2 (en) | 1981-02-27 |
| ES473175A1 (en) | 1979-10-16 |
| NZ188366A (en) | 1980-09-12 |
| RO75487A (en) | 1980-12-30 |
| AU3956278A (en) | 1980-03-13 |
| PL112630B1 (en) | 1980-10-31 |
| SE7809389L (en) | 1979-03-09 |
| PL209418A1 (en) | 1979-06-04 |
| JPS5448769A (en) | 1979-04-17 |
| GR70022B (en) | 1982-07-23 |
| FR2402656B1 (en) | 1981-12-24 |
| IL55490A (en) | 1982-05-31 |
| IT7827434A0 (en) | 1978-09-07 |
| NL7809137A (en) | 1979-03-12 |
| GB2008093B (en) | 1982-03-10 |
| ZA785059B (en) | 1980-04-30 |
| PT68502A (en) | 1978-10-01 |
| FR2402656A1 (en) | 1979-04-06 |
| HU179461B (en) | 1982-10-28 |
| IL55490A0 (en) | 1978-12-17 |
| AU517889B2 (en) | 1981-09-03 |
| IT1099496B (en) | 1985-09-18 |
| YU208478A (en) | 1982-10-31 |
| CA1095062A (en) | 1981-02-03 |
| DK396078A (en) | 1979-03-09 |
| DE2838496A1 (en) | 1979-03-22 |
| ATA642278A (en) | 1980-07-15 |
| BE870194A (en) | 1979-03-05 |
| DD137227A5 (en) | 1979-08-22 |
| AT360987B (en) | 1981-02-10 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| KR920701103A (en) | Improved vinyl ether production method | |
| Freedman | Tetraphenylcyclobutadiene Derivatives. III. Preparation of Precursors and Some Preliminary Investigations | |
| GB2008093A (en) | 2,6-Methano-2H-1-Benzocins | |
| KR870002069A (en) | Method for preparing 2- (3,5-dialkyl-4-hydroxyphenyl) indole derivative | |
| US4554358A (en) | 4-Chloro-4-methyl-5-methylene-1,3-dioxolane-2-one | |
| IE860840L (en) | Enantioselective process for producing¹i-beta-methylcarbapenem antiobiotic intermediates | |
| US4016175A (en) | Preparation of a 2-amino-pyrroline derivative | |
| Boyd et al. | Cyclization of Acylaminoalkanols to 2-Oxazolines1 | |
| GB985816A (en) | Substituted cyclobutanones | |
| US3419573A (en) | 3-chloro-4-oxy-1,2,5-thiadiazoles, and a process for preparing same | |
| US3137723A (en) | Boron containing heterocyclic compounds and process for producing them | |
| Alleston et al. | 472. Peroxides of elements other than carbon. Part VIII. Organoperoxides of tin | |
| Heine | The Isomerization of Aziridine Derivatives. VII | |
| US6677464B2 (en) | Process for preparation of 7-oxabicyclo[2.2.1]hept-5-ene-2-carboxylic acid derivatives | |
| JPH0796544B2 (en) | Method for ortho-thiocarboxylic acid esterification of phenylamines or phenols | |
| ES8101055A1 (en) | Process for making 5-mercapto-1,2,3-triazoles | |
| Popović-Djordjević et al. | High-yielding method for preparation of carbocyclic or N-containing heterocyclic β-keto esters using in situ activated sodium hydride in dimethyl sulphoxide | |
| HUT40995A (en) | Process for producing esters of 4-/acyloxy/-3-oxo-butiric acid | |
| GB969829A (en) | New phosphoric acid esters and process for their manufacture | |
| US3068266A (en) | 2-(substituted-benzyl)-1, 3-propanedisulfonates | |
| Sherman et al. | Three 2-fluoroalkyl-5-nitrofurans | |
| US3346591A (en) | Preparation of partly saturated 4-ketobenzothiophenes | |
| KR910008666B1 (en) | O-aryl n-aryl-n-substituted methyl carbamate derivatives | |
| Duus et al. | Studies on enethiols—VI: Rearrangement of α-thioacyllactones and α-thioacylthiollactones in acid alcoholic solution | |
| US3742011A (en) | Trinitrophenyl chloroformate and carbonate and a process for preparing same |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PCNP | Patent ceased through non-payment of renewal fee |