GB2006782A - Tetrazole derivatives - Google Patents

Tetrazole derivatives

Info

Publication number
GB2006782A
GB2006782A GB7842101A GB7842101A GB2006782A GB 2006782 A GB2006782 A GB 2006782A GB 7842101 A GB7842101 A GB 7842101A GB 7842101 A GB7842101 A GB 7842101A GB 2006782 A GB2006782 A GB 2006782A
Authority
GB
United Kingdom
Prior art keywords
carbon atoms
group
branched
straight
group containing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
GB7842101A
Other versions
GB2006782B (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
May and Baker Ltd
Original Assignee
May and Baker Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by May and Baker Ltd filed Critical May and Baker Ltd
Priority to GB7842101A priority Critical patent/GB2006782B/en
Publication of GB2006782A publication Critical patent/GB2006782A/en
Application granted granted Critical
Publication of GB2006782B publication Critical patent/GB2006782B/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
    • C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D257/04—Five-membered rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

New tetrazole derivatives of the general formula:- <IMAGE> [wherein R<1> represents a halogen atom, a straight- or branched-chain alkyl, alkoxy, alkylthio, alkylsulphinyl, alkylsulphonyl or alkylsulphamoyl group, each such group containing from 1 to 6 carbon atoms, a dialkylsulphamoyl, dialkylamino, or dialkylcarbamoyl group (wherein the two alkyl groups may be the same or different and each contains from 1 to 4 carbon atoms), a straight- or branched-chain alkanoyl, alkoxycarbonyl, alkoxycarbonylamino, alkylcarbamoyl or alkanoylamino group containing from 2 to 6 carbon atoms, a cycloalkylcarbonyl group containing from 3 to 8 carbon atoms in the cycloalkyl moiety, or a hydroxy, formyl, nitro, trifluoromethyl, trifluoroacetyl, aryl, benzyloxycarbonylamino, amino, sulphamoyl, cyano, tetrazol-5-yl, carboxy, carbamoyl, benzyloxy, aralkanoyl or aroyl group, or a group of the formula:- -CR<2>=NOR<3> II (wherein R<2> represents a hydrogen atom or a straight- or branched-chain alkyl group containing from 1 to 5 carbon atoms, an aryl, aralkyl or trifluoromethyl group, or a cycloalkyl group containing from 3 to 8 carbon atoms, and R<3> represents a hydrogen atom, or a straight- or branched-chain alkyl group containing from 1 to 6 carbon atoms optionally substituted by a phenyl group, or represents an aryl group optionally substituted by one or more substituents selected from halogen atoms and straight- or branched-chain alkyl and alkoxy groups containing from 1 to 6 carbon atoms and hydroxy, trifluoromethyl and nitro groups), and m represents zero or an integer 1, 2 or 3, the substituents R<1> being the same or different when m represents 2 or 3] posess pharmacological properties, in particular properties of value in the treatment of allergic conditions.
GB7842101A 1977-10-28 1978-10-26 Tetrazole derivatives Expired GB2006782B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
GB7842101A GB2006782B (en) 1977-10-28 1978-10-26 Tetrazole derivatives

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB4509777 1977-10-28
GB7842101A GB2006782B (en) 1977-10-28 1978-10-26 Tetrazole derivatives

Publications (2)

Publication Number Publication Date
GB2006782A true GB2006782A (en) 1979-05-10
GB2006782B GB2006782B (en) 1982-06-16

Family

ID=26265517

Family Applications (1)

Application Number Title Priority Date Filing Date
GB7842101A Expired GB2006782B (en) 1977-10-28 1978-10-26 Tetrazole derivatives

Country Status (1)

Country Link
GB (1) GB2006782B (en)

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4675333A (en) * 1983-12-16 1987-06-23 Lilly Industries Limited N-[4-[ω-(4-acyl-3-hydroxyphenoxy)alkoxy]-phenyl]1H-tetrazole-5-carboxamides and use thereof as anti-allergics
US4764525A (en) * 1987-02-25 1988-08-16 Warner-Lambert Company N-1H-tetrazol-5-ylbenzamides having use as antiallergy and antiinflammatory agents
US4808604A (en) * 1985-10-03 1989-02-28 Ciba-Geigy Corporation N-(substituted phenyl) tetrazol-5-yl carboxamides and anti-allergic use thereof
EP0323885A1 (en) * 1988-01-05 1989-07-12 May & Baker Limited New chemical process
EP0337701A2 (en) * 1988-04-11 1989-10-18 May & Baker Limited Use of tetrazole-5-carboxanilides in the treatment of transplant rejection or arthritic, autoimmune or connective tissue disorders
US4946855A (en) * 1987-12-14 1990-08-07 Sawai Pharmaceutical Co., Ltd. Carboxamide derivatives having tetrazole and thiazole rings and their use

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4675333A (en) * 1983-12-16 1987-06-23 Lilly Industries Limited N-[4-[ω-(4-acyl-3-hydroxyphenoxy)alkoxy]-phenyl]1H-tetrazole-5-carboxamides and use thereof as anti-allergics
US4808604A (en) * 1985-10-03 1989-02-28 Ciba-Geigy Corporation N-(substituted phenyl) tetrazol-5-yl carboxamides and anti-allergic use thereof
US4764525A (en) * 1987-02-25 1988-08-16 Warner-Lambert Company N-1H-tetrazol-5-ylbenzamides having use as antiallergy and antiinflammatory agents
US4946855A (en) * 1987-12-14 1990-08-07 Sawai Pharmaceutical Co., Ltd. Carboxamide derivatives having tetrazole and thiazole rings and their use
EP0323885A1 (en) * 1988-01-05 1989-07-12 May & Baker Limited New chemical process
EP0337701A2 (en) * 1988-04-11 1989-10-18 May & Baker Limited Use of tetrazole-5-carboxanilides in the treatment of transplant rejection or arthritic, autoimmune or connective tissue disorders
EP0337701A3 (en) * 1988-04-11 1991-02-06 May & Baker Limited Use of tetrazole-5-carboxanilides in the treatment of transplant rejection or arthritic, autoimmune or connective tissue disorders

Also Published As

Publication number Publication date
GB2006782B (en) 1982-06-16

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Legal Events

Date Code Title Description
PCNP Patent ceased through non-payment of renewal fee