GB2006185A - Method for producing purine arabinosides - Google Patents
Method for producing purine arabinosidesInfo
- Publication number
- GB2006185A GB2006185A GB7832560A GB7832560A GB2006185A GB 2006185 A GB2006185 A GB 2006185A GB 7832560 A GB7832560 A GB 7832560A GB 7832560 A GB7832560 A GB 7832560A GB 2006185 A GB2006185 A GB 2006185A
- Authority
- GB
- United Kingdom
- Prior art keywords
- producing purine
- purine arabinosides
- arabinosides
- purine
- producing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/26—Preparation of nitrogen-containing carbohydrates
- C12P19/28—N-glycosides
- C12P19/38—Nucleosides
- C12P19/40—Nucleosides having a condensed ring system containing a six-membered ring having two nitrogen atoms in the same ring, e.g. purine nucleosides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/16—Purine radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Zoology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Microbiology (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
Abstract
A 9-( beta -D-arabinofuranosyl) purine which is optionally substituted at the 2,6-and/or 8-position can be produced by reacting an arabinose donor with a purine source in the presence of an enzyme capable of effecting transarabinosylation.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP9576677A JPS5432695A (en) | 1977-08-10 | 1977-08-10 | Preparation of purine arabinosides |
JP15873877A JPS5492695A (en) | 1977-12-28 | 1977-12-28 | 2-substituted hypoxanthinearabinoside and its preparation |
JP180278A JPS5495793A (en) | 1978-01-11 | 1978-01-11 | Preparation of purine arabinoside |
Publications (2)
Publication Number | Publication Date |
---|---|
GB2006185A true GB2006185A (en) | 1979-05-02 |
GB2006185B GB2006185B (en) | 1982-04-28 |
Family
ID=27275082
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB7832560A Expired GB2006185B (en) | 1977-08-10 | 1978-08-08 | Method for producing purine arabinosides |
Country Status (5)
Country | Link |
---|---|
CA (1) | CA1120876A (en) |
DE (1) | DE2835151A1 (en) |
FR (1) | FR2400033A1 (en) |
GB (1) | GB2006185B (en) |
NL (1) | NL7808321A (en) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1464708A1 (en) * | 2003-04-03 | 2004-10-06 | Pro. Bio. Sint. S.p.A. | A process for the preparation of fludarabine phosphate from 2-fluoroadenine |
RU2563257C1 (en) * | 2014-11-07 | 2015-09-20 | Федеральное государственное бюджетное учреждение науки Институт биоорганической химии им. академиков М.М. Шемякина и Ю.А. Овчинникова РАН (ИБХ РАН) | METHOD OF PRODUCING 9-(BETA-D-ARABINOFURANOSYL)-6-(Nα-L-SERYLAMIDO)-2-CHLOROPURINE |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3379274D1 (en) * | 1982-04-01 | 1989-04-06 | Yamasa Shoyu Kk | Process for producing 3'-deoxyguanosine |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3269917A (en) * | 1963-03-18 | 1966-08-30 | Takeda Chemical Industries Ltd | Process for producing purine-nucleosides |
AT281301B (en) * | 1966-12-30 | 1970-05-11 | Parke Davis & Co | Process for the preparation of 9- (β-arabinofuranosyl) adenine |
-
1978
- 1978-08-08 GB GB7832560A patent/GB2006185B/en not_active Expired
- 1978-08-09 NL NL7808321A patent/NL7808321A/en not_active Application Discontinuation
- 1978-08-09 CA CA000309031A patent/CA1120876A/en not_active Expired
- 1978-08-10 DE DE19782835151 patent/DE2835151A1/en active Granted
- 1978-08-10 FR FR7823633A patent/FR2400033A1/en active Granted
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1464708A1 (en) * | 2003-04-03 | 2004-10-06 | Pro. Bio. Sint. S.p.A. | A process for the preparation of fludarabine phosphate from 2-fluoroadenine |
WO2004087939A1 (en) * | 2003-04-03 | 2004-10-14 | Pro.Bio.Sint. S.P.A. | A process for the preparation of fludarabine phosphate from 2-fluoroadenine and fludarabine phosphate salts with amines or ammonia |
RU2563257C1 (en) * | 2014-11-07 | 2015-09-20 | Федеральное государственное бюджетное учреждение науки Институт биоорганической химии им. академиков М.М. Шемякина и Ю.А. Овчинникова РАН (ИБХ РАН) | METHOD OF PRODUCING 9-(BETA-D-ARABINOFURANOSYL)-6-(Nα-L-SERYLAMIDO)-2-CHLOROPURINE |
Also Published As
Publication number | Publication date |
---|---|
FR2400033B1 (en) | 1982-07-30 |
DE2835151A1 (en) | 1979-02-22 |
GB2006185B (en) | 1982-04-28 |
DE2835151C2 (en) | 1988-07-14 |
NL7808321A (en) | 1979-02-13 |
FR2400033A1 (en) | 1979-03-09 |
CA1120876A (en) | 1982-03-30 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PE20 | Patent expired after termination of 20 years |
Effective date: 19980807 |