GB2002385B - Steroid derivatives and their use in radioimmunoassays - Google Patents

Steroid derivatives and their use in radioimmunoassays

Info

Publication number
GB2002385B
GB2002385B GB7833217A GB7833217A GB2002385B GB 2002385 B GB2002385 B GB 2002385B GB 7833217 A GB7833217 A GB 7833217A GB 7833217 A GB7833217 A GB 7833217A GB 2002385 B GB2002385 B GB 2002385B
Authority
GB
United Kingdom
Prior art keywords
radioimmunoassays
steroid derivatives
steroid
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB7833217A
Other versions
GB2002385A (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ER Squibb and Sons LLC
Original Assignee
ER Squibb and Sons LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/901,952 external-priority patent/US4230621A/en
Application filed by ER Squibb and Sons LLC filed Critical ER Squibb and Sons LLC
Publication of GB2002385A publication Critical patent/GB2002385A/en
Application granted granted Critical
Publication of GB2002385B publication Critical patent/GB2002385B/en
Expired legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
    • G01N33/743—Steroid hormones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/09—Preparation of carboxylic acids or their salts, halides or anhydrides from carboxylic acid esters or lactones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/347—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups
    • C07C51/353—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups by isomerisation; by change of size of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/347—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups
    • C07C51/367—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups by introduction of functional groups containing oxygen only in singly bound form
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J19/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 by a lactone ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C07J5/0046—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa
    • C07J5/0053—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa not substituted in position 16
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005—Oxygen-containing hetero ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Urology & Nephrology (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Biotechnology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Cell Biology (AREA)
  • Endocrinology (AREA)
  • Microbiology (AREA)
  • Steroid Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
GB7833217A 1977-08-12 1978-08-14 Steroid derivatives and their use in radioimmunoassays Expired GB2002385B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US82401677A 1977-08-12 1977-08-12
US05/901,952 US4230621A (en) 1978-05-01 1978-05-01 Steroid derivatives and their use in radioimmunoassays

Publications (2)

Publication Number Publication Date
GB2002385A GB2002385A (en) 1979-02-21
GB2002385B true GB2002385B (en) 1982-02-24

Family

ID=27124779

Family Applications (2)

Application Number Title Priority Date Filing Date
GB7833217A Expired GB2002385B (en) 1977-08-12 1978-08-14 Steroid derivatives and their use in radioimmunoassays
GB7921396A Expired GB2027425B (en) 1977-08-12 1978-08-14 Glutaric acid and anhydride dervatives

Family Applications After (1)

Application Number Title Priority Date Filing Date
GB7921396A Expired GB2027425B (en) 1977-08-12 1978-08-14 Glutaric acid and anhydride dervatives

Country Status (7)

Country Link
JP (1) JPS5436247A (en)
CA (1) CA1118409A (en)
DE (1) DE2834516A1 (en)
FR (1) FR2400035A1 (en)
GB (2) GB2002385B (en)
IT (1) IT7850710A0 (en)
NL (1) NL7808393A (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4323511A (en) * 1978-05-22 1982-04-06 E. R. Squibb & Sons, Inc. Steroid derivatives and their use in radioimmunoassays
US4209614A (en) * 1978-05-30 1980-06-24 E. R. Squibb & Sons, Inc. Vitamin B12 derivative suitable for radiolabeling
US4243608A (en) * 1979-05-14 1981-01-06 E. R. Squibb & Sons, Inc. 3-(4-Hydroxyphenyl)pentanedioic acid, monohydrazide, derivatives and analogs
US4366143A (en) * 1979-09-24 1982-12-28 Amersham International Public Limited Company Assay for the free portion of substances in biological fluids
JPS58194900A (en) * 1982-05-10 1983-11-12 Shionogi & Co Ltd 4- or 6-substituted aldosterones, its preparation and method for using the same in immunoassay
JPS59228097A (en) * 1983-06-07 1984-12-21 横河電機株式会社 Paper thickness profile control apparatus
JPS61108794A (en) * 1984-08-08 1986-05-27 インパクト　システムズ　インコ−ポレ−テツド Thickness control apparatus and method
JP2015193545A (en) * 2014-03-31 2015-11-05 国立大学法人京都大学 2-(3-pyridinyl)-1h-benzimidazole derivative compound, and radioactive pharmaceuticals containing the same

Also Published As

Publication number Publication date
GB2027425B (en) 1982-03-03
FR2400035B1 (en) 1981-02-13
DE2834516A1 (en) 1979-02-22
GB2027425A (en) 1980-02-20
CA1118409A (en) 1982-02-16
GB2002385A (en) 1979-02-21
IT7850710A0 (en) 1978-08-11
FR2400035A1 (en) 1979-03-09
JPS5436247A (en) 1979-03-16
NL7808393A (en) 1979-02-14

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Legal Events

Date Code Title Description
PCNP Patent ceased through non-payment of renewal fee