GB1589585A - 12a-halocorticoids - Google Patents
12a-halocorticoids Download PDFInfo
- Publication number
- GB1589585A GB1589585A GB28994/77A GB2899477A GB1589585A GB 1589585 A GB1589585 A GB 1589585A GB 28994/77 A GB28994/77 A GB 28994/77A GB 2899477 A GB2899477 A GB 2899477A GB 1589585 A GB1589585 A GB 1589585A
- Authority
- GB
- United Kingdom
- Prior art keywords
- compound
- methyl
- dione
- general formula
- pregnadiene
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
- C07J71/0005—Oxygen-containing hetero ring
- C07J71/001—Oxiranes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
- C07J5/0007—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond not substituted in position 17 alfa
- C07J5/0023—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond not substituted in position 17 alfa substituted in position 16
- C07J5/003—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond not substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group including 16-alkylidene substitutes
- C07J5/0038—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond not substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group including 16-alkylidene substitutes by an alkyl group
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Pain & Pain Management (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Rheumatology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Steroid Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE2632678A DE2632678C2 (de) | 1976-07-16 | 1976-07-16 | 6α-Fluor-12α-Halogen-Kortikoide und Verfahren zu ihrer Herstellung |
Publications (1)
Publication Number | Publication Date |
---|---|
GB1589585A true GB1589585A (en) | 1981-05-13 |
Family
ID=5983515
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB28994/77A Expired GB1589585A (en) | 1976-07-16 | 1977-07-11 | 12a-halocorticoids |
Country Status (11)
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB2244000A (en) * | 1990-05-18 | 1991-11-20 | Teasdale S | Mattress |
US9744168B2 (en) | 2011-10-19 | 2017-08-29 | Galderma Laboratories, Inc. | Method of reducing facial flushing associated with systemic use of phosphodiesterase type 5 inhibitors |
US9861631B2 (en) | 2010-03-26 | 2018-01-09 | Galderma Laboratories, L.P. | Methods and compositions for safe and effective treatment of erythema |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3053837A (en) * | 1958-10-01 | 1962-09-11 | Olin Mathieson | 16, 17-acetal and ketal derivatives of 6alpha, 12alpha-dihalo-16alpha, 17alpha-dihydroxy steroids of the pregnane series; and intermediates therefor |
GB1179547A (en) * | 1965-12-22 | 1970-01-28 | Squibb & Sons Inc | 01beta,12beta-Oxido-16alpha-Methyl-Pregnenes |
-
1976
- 1976-07-16 DE DE2632678A patent/DE2632678C2/de not_active Expired
-
1977
- 1977-07-11 GB GB28994/77A patent/GB1589585A/en not_active Expired
- 1977-07-12 CH CH861277A patent/CH627191A5/de not_active IP Right Cessation
- 1977-07-13 AT AT504777A patent/AT355743B/de not_active IP Right Cessation
- 1977-07-14 LU LU77768A patent/LU77768A1/xx unknown
- 1977-07-15 IT IT25805/77A patent/IT1125789B/it active
- 1977-07-15 DK DK323877A patent/DK323877A/da not_active Application Discontinuation
- 1977-07-15 NL NL7707920A patent/NL7707920A/xx not_active Application Discontinuation
- 1977-07-15 BE BE179386A patent/BE856862A/xx unknown
- 1977-07-15 JP JP8493377A patent/JPS5315361A/ja active Pending
- 1977-07-18 FR FR7721933A patent/FR2358421A1/fr active Granted
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB2244000A (en) * | 1990-05-18 | 1991-11-20 | Teasdale S | Mattress |
US9861631B2 (en) | 2010-03-26 | 2018-01-09 | Galderma Laboratories, L.P. | Methods and compositions for safe and effective treatment of erythema |
US9861632B2 (en) | 2010-03-26 | 2018-01-09 | Galderma Laboratories, L.P. | Methods and compositions for safe and effective treatment of erythema |
US9744168B2 (en) | 2011-10-19 | 2017-08-29 | Galderma Laboratories, Inc. | Method of reducing facial flushing associated with systemic use of phosphodiesterase type 5 inhibitors |
Also Published As
Publication number | Publication date |
---|---|
CH627191A5 (en) | 1981-12-31 |
DE2632678A1 (de) | 1978-01-26 |
ATA504777A (de) | 1979-08-15 |
LU77768A1 (US06650917-20031118-M00005.png) | 1977-10-17 |
NL7707920A (nl) | 1978-01-18 |
IT1125789B (it) | 1986-05-14 |
AT355743B (de) | 1980-03-25 |
JPS5315361A (en) | 1978-02-13 |
FR2358421A1 (fr) | 1978-02-10 |
BE856862A (fr) | 1978-01-16 |
DE2632678C2 (de) | 1986-02-27 |
DK323877A (da) | 1978-01-17 |
FR2358421B1 (US06650917-20031118-M00005.png) | 1979-05-11 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PS | Patent sealed | ||
PCNP | Patent ceased through non-payment of renewal fee |