GB1585768A - Microtitration plate - Google Patents

Microtitration plate Download PDF

Info

Publication number
GB1585768A
GB1585768A GB5265376A GB5265376A GB1585768A GB 1585768 A GB1585768 A GB 1585768A GB 5265376 A GB5265376 A GB 5265376A GB 5265376 A GB5265376 A GB 5265376A GB 1585768 A GB1585768 A GB 1585768A
Authority
GB
United Kingdom
Prior art keywords
wells
microtitration plate
hereof
cover strip
microtitration
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB5265376A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Dynatech Holdings Ltd
Original Assignee
Dynatech Holdings Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dynatech Holdings Ltd filed Critical Dynatech Holdings Ltd
Priority to GB5265376A priority Critical patent/GB1585768A/en
Priority to US05/817,748 priority patent/US4154795A/en
Priority to DE19772733214 priority patent/DE2733214A1/en
Priority to IT46881/77A priority patent/IT1117287B/en
Priority to NL7708176A priority patent/NL7708176A/en
Priority to ES460956A priority patent/ES460956A1/en
Priority to FR7722507A priority patent/FR2359422A1/en
Publication of GB1585768A publication Critical patent/GB1585768A/en
Priority to US07/213,491 priority patent/USRE34133E/en
Expired legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/508—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above
    • B01L3/5085—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above for multiple samples, e.g. microtitration plates
    • B01L3/50855—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above for multiple samples, e.g. microtitration plates using modular assemblies of strips or of individual wells
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/508—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above
    • B01L3/5085—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above for multiple samples, e.g. microtitration plates
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N31/00—Investigating or analysing non-biological materials by the use of the chemical methods specified in the subgroup; Apparatus specially adapted for such methods
    • G01N31/20—Investigating or analysing non-biological materials by the use of the chemical methods specified in the subgroup; Apparatus specially adapted for such methods using microanalysis, e.g. drop reaction

Description

(54) MICROTITRATION PLATE (71) We, DYNATECH HOLDINGS LIMITED, a Guernsey Company of Abacus Chambers, Smith Street, St. Peter Port, Guernsey, Channel Islands, do hereby declare the invention for which we pray that a patent may be granted to us, and the method by which it is performed to be particularly described in and by the following statement: This invention relates to a microtitration or microtest plate, for example, for use in conducting body fluid investigations, such as complement fixation tests, hemagglutinition tests, hemagglutinition inhibition tests and metabolic inhibition tests and immunochemical and both isotopic and non-isotopic immuno assays. More particularly, the invention relates to improvements in or modifications of the invention disclosed in our copending patent application No. 30543/77 (Serial No. 1 584 589).
Our aforementioned application describes and claims a microtitration plate comprising a tray formed as a one piece moulding and having a multiplicity of compartments arranged in rows on the tray, and a multiplicity of individual wells, each well being supported in an upright position in a compartment. The tray may be moulded from foam plastics material and the wells from a rigid material such as P.V.C. or polystyrene. In one embodiment, the bottoms of the compartments have holes therethrough to enable readings to be taken through the well bases, which may be flat, conical or hemispherical, from the bottom of the tray.
Although such microtitration plates have a greater degree of versatility than other plates known to the applicants, they do not lend themselves to rapid assembly of the trays and wells.
The present invention has for an object to alleviate this problem and, to this end, the invention consists in a microtitration plate as claimed in our aforementioned application, wherein at least some of the wells are integrally connected with one another. For example, the wells may be integrally moulded and be interconnected by means of stems, webs, strips or the like of the moulding material, such as, mould flashings extending between the individual wells.
The invention enables the wells to be more easily manipulated and more rapidly fitted into and removed from the compartments in the tray.
The wells may be integrally moulded in any convenient formation, for example, in a single row or a plurality of rows connected to form a strip or block of wells.
An embodiment of the invention will now be described, by way of example, with reference to the accompanying drawing which is a plan view of a microtitration plate according to the invention.
The microtitration plate shown in the drawing comprises a tray 1 moulded from polystyrene foam or flexible silicone rubber and having a tray recess 2. The tray recess 2 has a multiplicity of compartments 4 arranged in twelve rows with eight compartments in each row and defined by rows and columns of upstanding posts 6a and 6b integrally moulded with the base of the recess. Supported in the compartments 4 are a multiplicity of wells 5 made of glass, rigid P.V.C. or polystyrene, for example, for receiving a sample of a patient's body fluid to be tested. All the wells 5 are moulded integrally with one another and are interconnected by means of stems 5a formed, for example by mould flashings. Thus, all the individual wells can be simultaneously fitted into the compartments of the tray recess 2 so that assembly of the tray and wells can be simply and rapidly achieved.The stems 5a may easily be broken to enable one or more wells to be separated from each other when required.
Alternatively, the wells may be integrally formed in single rows or in a plurality of rows connected to form a strip of wells.
One or more rows of the wells may be sealed by at least one adhesive cover strip disposed across the tops of the wells, as described in our aforementioned application. The or each cover strip may have perforations around the individual wells. Alternatively, one or more rows of wells may be sealed by plugs carried by a cover strip to seal one or more strips of wells, the or each cover strip preferably having perforations around the plugs.
WHAT WE CLAIM IS: 1. A microtitration plate as claimed in any one of the claims of our copending patent application No. 30543/77 (Serial No.
1 584 589), wherein at least some of the wells are integrally connected with one another.
2. A microtitration plate as claimed in claim 1 hereof, wherein said at least some wells are integrally connected in one or more rows.
3. A microtitration plate as claimed in claim 1 or 2 hereof, wherein said at least some wells are integrally moulded and are interconnected by means of stems, webs or strips of the moulding material, whereby the wells are separable from one another.
4. A microtitration plate as claimed in claim 1, 2 or 3 hereof, as appendant to any one of claims 1 to 9 of our copending application, wherein said at least some wells are sealed by at least one adhesive cover strip.
5. A microtitration plate as claimed in claim 4 hereof, wherein the or each cover strip has perforations around the wells.
6. A microtitration plate as claimed in claim 1, 2 or 3 hereof, as appendant to any one of claims 1 to 9 of our copending application, wherein said at least some wells are sealed by plugs carried by at least one cover strip.
7. A microtitration plate as claimed in claim 6 hereof, wherein the or each cover strip has perforations around the plugs.
8. A microtitration plate substantially as hereinbefore described with reference to the accompanying drawings.
**WARNING** end of DESC field may overlap start of CLMS **.

Claims (8)

**WARNING** start of CLMS field may overlap end of DESC **. strip preferably having perforations around the plugs. WHAT WE CLAIM IS: 1. A microtitration plate as claimed in any one of the claims of our copending patent application No. 30543/77 (Serial No.
1 584 589), wherein at least some of the wells are integrally connected with one another.
2. A microtitration plate as claimed in claim 1 hereof, wherein said at least some wells are integrally connected in one or more rows.
3. A microtitration plate as claimed in claim 1 or 2 hereof, wherein said at least some wells are integrally moulded and are interconnected by means of stems, webs or strips of the moulding material, whereby the wells are separable from one another.
4. A microtitration plate as claimed in claim 1, 2 or 3 hereof, as appendant to any one of claims 1 to 9 of our copending application, wherein said at least some wells are sealed by at least one adhesive cover strip.
5. A microtitration plate as claimed in claim 4 hereof, wherein the or each cover strip has perforations around the wells.
6. A microtitration plate as claimed in claim 1, 2 or 3 hereof, as appendant to any one of claims 1 to 9 of our copending application, wherein said at least some wells are sealed by plugs carried by at least one cover strip.
7. A microtitration plate as claimed in claim 6 hereof, wherein the or each cover strip has perforations around the plugs.
8. A microtitration plate substantially as hereinbefore described with reference to the accompanying drawings.
GB5265376A 1976-07-23 1976-12-16 Microtitration plate Expired GB1585768A (en)

Priority Applications (8)

Application Number Priority Date Filing Date Title
GB5265376A GB1585768A (en) 1976-12-16 1976-12-16 Microtitration plate
US05/817,748 US4154795A (en) 1976-07-23 1977-07-21 Microtest plates
DE19772733214 DE2733214A1 (en) 1976-12-16 1977-07-22 MICRO TEST PLATE
IT46881/77A IT1117287B (en) 1976-07-23 1977-07-22 MICRO TEST PLATE
NL7708176A NL7708176A (en) 1976-07-23 1977-07-22 PLATE FOR MICRO-TESTS.
ES460956A ES460956A1 (en) 1976-07-23 1977-07-22 Microtest plates
FR7722507A FR2359422A1 (en) 1976-07-23 1977-07-22 PLATE FOR MICRO-TESTS
US07/213,491 USRE34133E (en) 1976-07-23 1988-06-30 Microtest plates

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB5265376A GB1585768A (en) 1976-12-16 1976-12-16 Microtitration plate

Publications (1)

Publication Number Publication Date
GB1585768A true GB1585768A (en) 1981-03-11

Family

ID=10464763

Family Applications (1)

Application Number Title Priority Date Filing Date
GB5265376A Expired GB1585768A (en) 1976-07-23 1976-12-16 Microtitration plate

Country Status (2)

Country Link
DE (1) DE2733214A1 (en)
GB (1) GB1585768A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8512652B2 (en) 1997-03-25 2013-08-20 Greiner Bio-One Gmbh Multiwell microplate with transparent bottom having a thickness less than 200 micrometers

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10160975A1 (en) * 2001-12-10 2003-06-18 Univ Schiller Jena Sample plate for use in dialysis systems

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8512652B2 (en) 1997-03-25 2013-08-20 Greiner Bio-One Gmbh Multiwell microplate with transparent bottom having a thickness less than 200 micrometers

Also Published As

Publication number Publication date
DE2733214A1 (en) 1978-06-29

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Legal Events

Date Code Title Description
PS Patent sealed
PCNP Patent ceased through non-payment of renewal fee