GB1569993A - Steroidal 16 -alkyl-(16a,17-b)naphthalenes - Google Patents

Steroidal 16 -alkyl-(16a,17-b)naphthalenes Download PDF

Info

Publication number
GB1569993A
GB1569993A GB46811/76A GB4681176A GB1569993A GB 1569993 A GB1569993 A GB 1569993A GB 46811/76 A GB46811/76 A GB 46811/76A GB 4681176 A GB4681176 A GB 4681176A GB 1569993 A GB1569993 A GB 1569993A
Authority
GB
United Kingdom
Prior art keywords
hydrogen
steroid
hydroxy
alkyl
halogen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB46811/76A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ER Squibb and Sons LLC
Original Assignee
ER Squibb and Sons LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ER Squibb and Sons LLC filed Critical ER Squibb and Sons LLC
Publication of GB1569993A publication Critical patent/GB1569993A/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J71/00Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0036Nitrogen-containing hetero ring
    • C07J71/0042Nitrogen only
    • C07J71/0052Nitrogen only at position 16(17)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J13/00Normal steroids containing carbon, hydrogen, halogen or oxygen having a carbon-to-carbon double bond from or to position 17
    • C07J13/005Normal steroids containing carbon, hydrogen, halogen or oxygen having a carbon-to-carbon double bond from or to position 17 with double bond in position 16 (17)
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J53/00Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by condensation with a carbocyclic rings or by formation of an additional ring by means of a direct link between two ring carbon atoms, including carboxyclic rings fused to the cyclopenta(a)hydrophenanthrene skeleton are included in this class
    • C07J53/002Carbocyclic rings fused

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Rheumatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
GB46811/76A 1975-11-24 1976-11-10 Steroidal 16 -alkyl-(16a,17-b)naphthalenes Expired GB1569993A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/634,684 US3994935A (en) 1975-11-24 1975-11-24 Steroidal 16β-alkyl[16α,17-b]naphthalenes

Publications (1)

Publication Number Publication Date
GB1569993A true GB1569993A (en) 1980-06-25

Family

ID=24544809

Family Applications (1)

Application Number Title Priority Date Filing Date
GB46811/76A Expired GB1569993A (en) 1975-11-24 1976-11-10 Steroidal 16 -alkyl-(16a,17-b)naphthalenes

Country Status (7)

Country Link
US (1) US3994935A (enExample)
JP (1) JPS5265260A (enExample)
CA (1) CA1088516A (enExample)
DE (1) DE2653405A1 (enExample)
FR (1) FR2332021A1 (enExample)
GB (1) GB1569993A (enExample)
MX (1) MX4033E (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3510300A1 (de) * 1985-03-22 1986-09-25 Alfred Teves GmbH & Co oHG, 5275 Bergneustadt Befestigungsschraube, insbesondere fuer stossfaenger von kraftfahrzeugen

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4091036A (en) * 1977-05-12 1978-05-23 E. R. Squibb & Sons, Inc. 17-Alkylthio (and arylthio)-1',2',3',4'-tetrahydroandrosteno [16 α, 17 α-b]naphthalenes and derivatives
US4232013A (en) * 1977-12-03 1980-11-04 Lark S.P.A. 16,17-Pyrazolino- and 16,17-isopyrazolino-1,4-pregnadiene derivatives
US4265815A (en) * 1980-03-31 1981-05-05 E. R. Squibb & Sons, Inc. 17-(Substituted thio)androst-4-ene[16,17,-b]-[1,4]benzodioxin-3-ones
DE102005061528B8 (de) * 2005-12-22 2010-06-10 Siemens Ag Piezokeramisches Bauteil mit Bleizirkonattitanat mit Eisen-Wolfram-Dotierung, Verfahren zum Herstellen des piezokeramischen Bauteils und seine Verwendung
US8316865B2 (en) 2008-07-31 2012-11-27 Mcneil-Ppc, Inc. Process for winding dental tape
HUE038046T2 (hu) * 2010-12-17 2018-09-28 Reata Pharmaceuticals Inc Antioxidáns gyulladáscsökkentõ pirazolil és pirimidinil triciklusos enonok

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3944584A (en) * 1975-02-03 1976-03-16 E. R. Squibb & Sons, Inc. Steroidal (16α,17-d)cyclohexenes

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3510300A1 (de) * 1985-03-22 1986-09-25 Alfred Teves GmbH & Co oHG, 5275 Bergneustadt Befestigungsschraube, insbesondere fuer stossfaenger von kraftfahrzeugen

Also Published As

Publication number Publication date
US3994935A (en) 1976-11-30
MX4033E (es) 1981-11-18
FR2332021A1 (fr) 1977-06-17
FR2332021B1 (enExample) 1982-08-13
JPS5265260A (en) 1977-05-30
CA1088516A (en) 1980-10-28
DE2653405A1 (de) 1977-05-26

Similar Documents

Publication Publication Date Title
EP0075189A1 (en) 3-Beta,7-beta,15-alpha-trihydroxy-5-androsten-17-one, its 3,15-dipivalate, and its preparation
TWI280133B (en) Process for preparing C-7 substituted steroids
US4091036A (en) 17-Alkylthio (and arylthio)-1',2',3',4'-tetrahydroandrosteno [16 α, 17 α-b]naphthalenes and derivatives
TWI283245B (en) Processes to prepare eplerenone
GB1569993A (en) Steroidal 16 -alkyl-(16a,17-b)naphthalenes
JPS6340198B2 (enExample)
JPS6323895A (ja) 新規な6−もしくは7−メチレンアンドロスタ−1,4−ジエン−3,17−ジオン誘導体およびその製造方法
US4018774A (en) Steroidal [16α,17-d]isoxazolidines
GB2152058A (en) 17-ethynyl-6-fluoro steroids, their preparation and use
PT1817326E (pt) Processo industrial de preparação da gama-lactona do ácido 17-hidroxi, 6-beta,7-beta, 15-beta, 16-beta-bismetileno-3-oxo-17- alfa-pregn-4-eno-21-carboxílico e intermediários chave para este processo
Cui et al. Synthesis of polyhydroxysterols (III): synthesis and structural elucidation of 24-methylenecholest-4-en-3β, 6α-diol
US3937720A (en) Steroidal[16α,17-β]naphthalenes
Blunt et al. Reaction of epoxides—XI: A novel “backbone rearrangement” of the cholestane skeleton
GB1582551A (en) Steroidal (16a, 17-c) (2h) pyrroles
ApSimon et al. Marine Organic Chemistry. II. Synthesis of 3β, 6α-Dihydroxy-5α-pregn-9 (11)-en-20-one, the major Sapogenin of the Starfish Asterias forbesi
US3271390A (en) Sulfurenic acid and derivatives thereof
HU197924B (en) Process for producing new steroids containing sulfinyl group in the 23-position
Kongkathip et al. Synthesis of cytotoxic novel 9, 11-secosterol analogs: Structure/activity studies
Kovganko et al. Novel synthesis of (24R, 6E)-24-ethylcholest-6-hydroxyimino-4-en-3-one, a steroidal oxime from Cinachyrella spp. sponges
Lu et al. Stereospecific synthesis and rearrangement of 22S-23-acetylsapogenins
US4113722A (en) Steroidal[16α,17-b]benzodioxins
US3945997A (en) Steroidal bicyclic dioxanes
Wan et al. A facile total synthesis of drospirenone isomers containing 14β-hydrogen configuration
Hughes et al. Totally synthetic steroid hormones. Part XIV.(±)-18-methyl-19-norprogesterone, 18-methyl-19-nordesoxycorticosterone and related compounds
Seo et al. Direct evidence for three 1, 2-hydride migrations in the biosynthesis of cycloartenol from [2-13 C 2 H 3] acetate in tissue cultures of Physalis peruviana

Legal Events

Date Code Title Description
PS Patent sealed [section 19, patents act 1949]
PCNP Patent ceased through non-payment of renewal fee