GB1549345A - Gonococcal pili processes for the preparation thereof and the use thereof - Google Patents

Gonococcal pili processes for the preparation thereof and the use thereof

Info

Publication number
GB1549345A
GB1549345A GB16688/76A GB1668876A GB1549345A GB 1549345 A GB1549345 A GB 1549345A GB 16688/76 A GB16688/76 A GB 16688/76A GB 1668876 A GB1668876 A GB 1668876A GB 1549345 A GB1549345 A GB 1549345A
Authority
GB
United Kingdom
Prior art keywords
pili
processes
preparation
gonococcal pili
gonococcal
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB16688/76A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bactex Inc
Original Assignee
Bactex Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bactex Inc filed Critical Bactex Inc
Publication of GB1549345A publication Critical patent/GB1549345A/en
Expired legal-status Critical Current

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/571Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses for venereal disease, e.g. syphilis, gonorrhoea
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/22Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Neisseriaceae (F)
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/12Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • C07K16/1203Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria
    • C07K16/1217Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria from Neisseriaceae (F)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • C12N1/205Bacterial isolates
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P1/00Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes
    • C12P1/04Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes by using bacteria
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C12Q1/04Determining presence or kind of microorganism; Use of selective media for testing antibiotics or bacteriocides; Compositions containing a chemical indicator therefor
    • C12Q1/12Nitrate to nitrite reducing bacteria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12RINDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00Microorganisms ; Processes using microorganisms
    • C12R2001/01Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/36Neisseria

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Biomedical Technology (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Physics & Mathematics (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Analytical Chemistry (AREA)
  • Toxicology (AREA)
  • General Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cell Biology (AREA)
  • Mycology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Food Science & Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pathology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)

Abstract

Pili from Neisseria gonorrhoeae are prepared by the artificial cultivation of N. gonorrhoeae bacteria and processing of the culture to isolate the pili. The pili which are obtained are capable of forming antibodies in the organism and can be used for serological and immunological purposes. For diagnosis in vitro, the pili are brought into contact with the serum to be investigated in the absence of any cell residues.
GB16688/76A 1975-04-25 1976-04-23 Gonococcal pili processes for the preparation thereof and the use thereof Expired GB1549345A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US57120075A 1975-04-25 1975-04-25

Publications (1)

Publication Number Publication Date
GB1549345A true GB1549345A (en) 1979-08-08

Family

ID=24282722

Family Applications (1)

Application Number Title Priority Date Filing Date
GB16688/76A Expired GB1549345A (en) 1975-04-25 1976-04-23 Gonococcal pili processes for the preparation thereof and the use thereof

Country Status (14)

Country Link
JP (1) JPS51130525A (en)
AU (1) AU509621B2 (en)
BE (1) BE841068A (en)
CA (1) CA1050423A (en)
CH (1) CH634923A5 (en)
DE (1) DE2617870A1 (en)
ES (1) ES447313A1 (en)
FR (1) FR2308377A1 (en)
GB (1) GB1549345A (en)
HU (1) HU174887B (en)
IE (1) IE44448B1 (en)
IL (1) IL49459A (en)
NL (1) NL7604311A (en)
ZA (1) ZA762438B (en)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4454117A (en) * 1980-09-15 1984-06-12 Bactex, Inc. Immunization against infection by Escherichia coli
US4454116A (en) * 1977-11-23 1984-06-12 Bactex, Inc. Immunization of humans against enterotoxogenic infection by Escherichia coli
WO1985005037A1 (en) * 1984-05-02 1985-11-21 Syn-Tek Ab Adhesin antigens, antibodies and dna fragment encoding the antigen, methods and means for diagnosis and immunization etc.
AU2003204738B2 (en) * 1998-04-29 2006-09-14 Wyeth Holdings Corporation Vaccines Containing Recombinant Pilin Against Neisseria Gonorrhoeae or Neisseria Meningitidis

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4203971A (en) * 1978-03-23 1980-05-20 Government Of The United States Neisseria gonorrhoeae vaccine
US4241045A (en) * 1978-05-15 1980-12-23 Research Corporation Purified antigen to test for Neisseria gonorrheae antibodies
EP0049945A3 (en) * 1980-09-15 1982-12-01 Bactex Incorporated Determining a hierarchy of piliated organisms and a vaccine prepared from such organisms
US5132205A (en) * 1988-10-07 1992-07-21 Eastman Kodak Company High ph extraction composition and its use to determine a chlamydial, gonococcal or herpes antigen
GB9417880D0 (en) * 1994-09-06 1994-10-26 Auspharm Int Ltd Vaccine

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3951748A (en) * 1974-11-11 1976-04-20 Medical Products, Inc. Sensitized matrix for detection of disease

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4454116A (en) * 1977-11-23 1984-06-12 Bactex, Inc. Immunization of humans against enterotoxogenic infection by Escherichia coli
US4454117A (en) * 1980-09-15 1984-06-12 Bactex, Inc. Immunization against infection by Escherichia coli
WO1985005037A1 (en) * 1984-05-02 1985-11-21 Syn-Tek Ab Adhesin antigens, antibodies and dna fragment encoding the antigen, methods and means for diagnosis and immunization etc.
US5804198A (en) * 1984-05-02 1998-09-08 Symbicom Aktiebolag Vaccines against disease caused by pathogenic pilus-forming bacteria
US6291649B1 (en) 1984-05-02 2001-09-18 Symbicom Aktiebolag Anti-bodies binding adhesin-derived antigens
AU2003204738B2 (en) * 1998-04-29 2006-09-14 Wyeth Holdings Corporation Vaccines Containing Recombinant Pilin Against Neisseria Gonorrhoeae or Neisseria Meningitidis

Also Published As

Publication number Publication date
NL7604311A (en) 1976-10-27
DE2617870A1 (en) 1976-12-30
CA1050423A (en) 1979-03-13
AU1332176A (en) 1977-10-27
IE44448B1 (en) 1981-12-02
BE841068A (en) 1976-10-25
ZA762438B (en) 1978-03-29
JPH0118080B2 (en) 1989-04-03
AU509621B2 (en) 1980-05-22
IL49459A (en) 1980-02-29
IL49459A0 (en) 1976-06-30
ES447313A1 (en) 1977-10-16
IE44448L (en) 1976-10-25
DE2617870C2 (en) 1988-09-22
HU174887B (en) 1980-04-28
FR2308377B1 (en) 1979-04-06
JPS51130525A (en) 1976-11-12
CH634923A5 (en) 1983-02-28
FR2308377A1 (en) 1976-11-19

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Legal Events

Date Code Title Description
PS Patent sealed [section 19, patents act 1949]
PCNP Patent ceased through non-payment of renewal fee